Results 101 to 110 of about 15,463 (165)

Sensitivity to microstimulation of somatosensory cortex distributed over multiple electrodes

Frontiers in Systems Neuroscience, 2015
Meaningful and repeatable tactile sensations can be evoked by electrically stimulating primary somatosensory cortex. Intracortical microstimulation (ICMS) may thus be a viable approach to restore the sense of touch in individuals who have lost it, for ...
Sungshin eKim, Thierri eCallier, Gregg A Tabot, Francesco V Tenore, Sliman J Bensmaia   +4 more
doaj   +1 more source

Injecting information in the cortical reach-to-grasp network is effective in ventral but not dorsal nodes

Cell Reports
Summary: Although control of movement involves many cortical association areas, bidirectional brain-machine interfaces (BMIs) typically decode movement intent from the motor cortex and deliver feedback information to the primary somatosensory cortex (S1).
Brandon M. Ruszala, Marc H. Schieber
doaj   +1 more source

Solving the problem of inception: a cross-species perspective on strategies for a mechanistic refinement of intracortical microstimulation

Journal of Neural Engineering
Objective. Microstimulation delivers electrical pulses directly into the brain, with one of its promises being to restore lost senses to millions of people. Yet a fundamental challenge remains: how do intracortical microstimulation (ICMS) patterns engage
Takashi D. Yoshida Kozai, B. M. Hooks, Alberto L. Vazquez, Omar A. Gharbawie, Chengcheng Huang, Emily L. Graczyk, Matthew A. Smith, D. Taylor, Ana G. Hernandez-Reynoso, A. London, P. Ford, E. Anderson, Xing Chen, Amy Irene Flick, Lisa S Parker, R. Gaunt   +15 more
semanticscholar   +1 more source

Spatiotemporal properties of cortical excitatory and inhibitory neuron activation by sustained and bursting electrical microstimulation

iScience
Summary: Intracortical microstimulation (ICMS) of sensory brain regions can create artificial sensations, yet these percepts fade with continued stimulation, suggesting dynamic changes in underlying neural activity. Using two-photon imaging in transgenic
Christopher L. Hughes, Kevin C. Stieger, Keying Chen, Alberto L. Vazquez, Takashi D.Y. Kozai   +4 more
doaj   +1 more source

Spatiotemporally distinctive astrocytic and neuronal responses to repetitive intracortical microstimulation

bioRxiv
Objective. Astrocytes are increasingly recognized as active modulators of neuronal synaptic transmission. Intracortical microstimulation (ICMS) is widely used to manipulate neuronal activity, yet the accompanying astrocytic responses remain poorly ...
David Grundfest, Kayeon Kim, Qinxue Wang, Alexandra Katherine Isis Yonza, Jeremi Tadeusz Podsiadlo, Le-Chan Tao, Xiao Zhang, Krzysztof Kucharz, Yan Zhang, An-Pan Han, Barbara Lind, Chang-Si Cai   +11 more
semanticscholar   +1 more source

Polymer-based flexible multi-shank probes for simultaneous intracortical microstimulation and two-photon calcium imaging

bioRxiv
Intracortical microstimulation is an essential tool for basic neuroscience and sensory restoration, yet the spatiotemporal effects of advanced multielectrode stimulation strategies on cortical networks remain poorly understood.
Eszter Nguyen, Balázs Barkóczi, Csaba Horváth, Linda Judák, Balázs Rózsa, Frederik Ceyssens, I. Ulbert, Lucia Wittner, Maarten Schelles, R. Fiáth   +9 more
semanticscholar   +1 more source

Continuous sensorimotor transformation enhances robustness of neural dynamics to perturbation in macaque motor cortex

Nature Communications
Neural activity in the motor cortex evolves dynamically to prepare and generate movement. Here, we investigate how motor cortical dynamics adapt to dynamic environments and whether these adaptations influence robustness against disruptions.
Cong Zheng, Qifan Wang, He Cui
doaj   +1 more source

Optimal interphase delay in biphasic current pulses facilitates neural circuit activation induced by microstimulation in the mouse visual cortex

Frontiers in Neuroscience
Cathodic-first biphasic current pulses are commonly employed in intracortical microstimulation. Due to the intricate arrangement of axons, somata, and dendrites in the cerebral cortex, membrane polarizations induced by the cathodic and subsequent anodic ...
Santa Fukuda, Yuki Hayashida
doaj   +1 more source

Electrolytic-microbubble dynamics delineate safety thresholds during intracortical microstimulation with flexible neural interfaces

bioRxiv
Intracortical microstimulation (ICMS) with ultraflexible neural electrodes enables low-threshold, chronically stable, and high-resolution modulation of neural circuits, providing a promising strategy for sensory restoration and closed-loop ...
A. Iliasov, Hao-Ran Ma, Fang-Yuan Li, Zhen Chen, Ming-Liang Xu, Chen-Hui Yu, Ru-Xin Li, Jinsong Wu, Fei He   +8 more
semanticscholar   +1 more source

Context is key to evoking natural touch experiences using intracortical microstimulation of the human somatosensory cortex

Brain Stimulation, 2023
Ceci Verbaarschot, V. Karapetyan, Charles M. Greenspon, M. Boninger, S. Bensmaia, Bettina Sorger, R. Gaunt   +6 more
semanticscholar   +1 more source