Results 51 to 60 of about 75,756 (284)

Stent-assisted reconstructive endovascular repair of intracranial aneurysms: long-term clinical and angiographic follow-up [PDF]

open access: yes, 2012
Background and Purpose: The development of self-expanding stents dedicated to intracranial use has significantly widened the applicability of endovascular therapy to many intracranial aneurysms.
VANNUCCI, STEFANO
core  

Sex Differential in 15-Hydroxyprostaglandin Dehydrogenase Levels in the Lumen of Human Intracranial Aneurysms. [PDF]

open access: yes, 2017
BACKGROUND: Aspirin is a promising medical therapy for the prevention of intracranial aneurysm (IA) rupture. Recently, we found that men have a better response to aspirin than women.
Chalouhi, Nohra   +6 more
core   +2 more sources

Assessment of acute headache in adults - what the general physician needs to know. [PDF]

open access: yes, 2018
Headache is common. Up to 5% of attendances to emergency departments and acute medical units are due to headache. Headache is classified as either primary (eg migraine, cluster headache) or secondary to another cause (eg meningitis, subarachnoid ...
Agrawal   +9 more
core   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

open access: yesThe Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna   +15 more
wiley   +1 more source

External Validation of the ELAPSS Score for Prediction of Unruptured Intracranial Aneurysm Growth Risk [PDF]

open access: yesJournal of Stroke, 2019
Background and Purpose Prediction of intracranial aneurysm growth risk can assist physicians in planning of follow-up imaging of conservatively managed unruptured intracranial aneurysms.
Mayte Sánchez van Kammen   +34 more
doaj   +1 more source

A Two-step Surface-based 3D Deep Learning Pipeline for Segmentation of Intracranial Aneurysms [PDF]

open access: yesarXiv, 2020
The exact shape of intracranial aneurysms is critical in medical diagnosis and surgical planning. While voxel-based deep learning frameworks have been proposed for this segmentation task, their performance remains limited. In this study, we offer a two-step surface-based deep learning pipeline that achieves significantly higher performance.
arxiv  

Proposal for Numerical Benchmarking of Fluid-Structure Interaction in Cerebral Aneurysms [PDF]

open access: yesarXiv, 2023
Computational fluid dynamics is intensively used to deepen the understanding of aneurysm growth and rupture in the attempt to support physicians during therapy planning. Numerous studies have assumed fully-rigid vessel walls in their simulations, whose sole hemodynamics may fail to provide a satisfactory criterion for rupture risk assessment. Moreover,
arxiv  

Plasma Soluble Human Elastin Fragments as an Intra-Aneurysmal Localized Biomarker for Ruptured Intracranial Aneurysm [PDF]

open access: yes, 2018
Background—Fragmentation of the tunica media is a hallmark of intracranial aneurysm formation, often leading to aneurysmal progression and subsequent rupture.
Allan, Lauren   +9 more
core   +1 more source

Safety, Tolerability, and Pharmacokinetics of Donanemab in Healthy Chinese Participants: A Phase 1, Randomized, Double‐Blind, Placebo‐Controlled Study

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Alzheimer's disease (AD), characterized by β‐amyloid (Aβ) plaques and neurofibrillary tangles, is the leading cause of dementia globally. Donanemab is a humanized immunoglobulin G1 in development as a treatment to slow AD progression. This study aimed to evaluate the safety, tolerability, pharmacokinetics (PKs), and immunogenicity of donanemab
Junyu Xu   +5 more
wiley   +1 more source

Beyond the virtual intracranial stenting challenge 2007: non-Newtonian and flow pulsatility effects [PDF]

open access: yes, 2010
The attached article is a post print version of the final published version which may be accessed at the link below. Crown Copyright (c) 2010 Published by Elsevier Ltd.
Atherton, MA   +3 more
core   +1 more source

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