Results 81 to 90 of about 84,766 (305)

Major PM2.5 components promote intracranial aneurysm via TP53: Insights from a comprehensive network analysis

Ecotoxicology and Environmental Safety
In this study, we combined network toxicology with two-sample Mendelian randomization (MR) to investigate the potential mechanisms by which major components of PM2.5 influence the development of intracranial aneurysms (IAs).
Guanhui Li, Keyu Yan, Yuxiang Sun, Longlong Tian, Shuai Wang, Guozhu Sun   +5 more
doaj   +1 more source

Acquired ptosis associated with oculomotor and contralateral facial nerve synkinesis: the first reported case [PDF]

, 2017
Evidence of oculomotor nerve (ON) synkinesis is a common occurrence following both acquired and congenital III nerve palsy. It is generally accepted that aberrant regeneration is the likely aetiology of synkinesis in acquired III nerve palsy, following ...
Conversi, Andrea, Di Taranto, Giuseppe, Fino, Pasquale, Gharbiya, Magda, Onesti, Maria Giuseppina, Scuderi, Nicolò, Tarallo, Mauro, Toscani, Marco   +7 more
core   +2 more sources

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

An overview of decision-making in cerebrovascular treatment strategies: Part I - unruptured aneurysms

Brain and Spine
Introduction: Unruptured intracranial aneurysm treatment has evolved over the last two centuries, starting from the introduction of aneurysm ligation and clipping, up until the inception of endovascular treatment and further advancements in both fields ...
Georges Versyck, Johannes van Loon, Robin Lemmens, Jelle Demeestere, Lawrence Bonne, Jo P. Peluso, Steven De Vleeschouwer   +6 more
doaj   +1 more source

Ruptured infective intracranial aneurysm with intracerebral hemorrhage in an infant

Journal of Medical Sciences, 2015
Intracranial aneurysms are rare in children. Less than 10% of pediatric intracranial aneurysms are infective aneurysms, and few cases of such aneurysms in infants have been reported in the literature.
Kin Sang Iao, Abel Po Hao Huang, Kuo Chuan Wang, Shih-Hung Yang   +3 more
doaj   +1 more source

Subarachnoid Haemorrhage in Malta : Are outcomes adversely affected due to lack of a local neurovascular service? [PDF]

, 2014
Objective: This study was performed to assess the incidence, treatment and outcome of non-traumatic Subarachnoid Haemorrhage (SAH) in an island which does not offer a neurovascular service and to determine whether such limitation is associated with a ...
Aquilina, Josanne, Dingli, Nicola, Galea Debono, Anthony, Vella, Malcolm, Vella, Norbert   +4 more
core  

Sex Differential in 15-Hydroxyprostaglandin Dehydrogenase Levels in the Lumen of Human Intracranial Aneurysms. [PDF]

, 2017
BACKGROUND: Aspirin is a promising medical therapy for the prevention of intracranial aneurysm (IA) rupture. Recently, we found that men have a better response to aspirin than women.
Chalouhi, Nohra, Hasan, David M., Jabbour, Pascal, Nakagawa, Daichi, Starke, Robert M., Torner, James, Zanaty, Mario   +6 more
core   +2 more sources

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source

The Risk of Multiple Intracranial Aneurysm Formation in Patients with Malignant Disease Undergoing Radiation Therapy: a Case Report and Literature Review

Acta Clinica Croatica, 2020
Neoplastic etiology of intracranial cerebral aneurysm is rare. Yet, the risk of its development is higher in malignant tumor patients receiving radiation therapy.
Krešimir Rotim, Bruno Splavski, Zlatko Trkanjec, Vladimir Kalousek, Ante Rotim, Tomislav Sajko   +5 more
doaj   +1 more source

Pregnancy and Delivery Outcomes in Vascular Ehlers–Danlos Syndrome: A Retrospective Multicentre Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective We aim to increase knowledge on pregnancy and delivery risks in vascular Ehlers–Danlos Syndrome (vEDS). Our outcomes can contribute to establishing future guidelines for pregnancy and delivery management in women with vEDS. Design Retrospective multicentre cohort study.
Lisa M. van den Bersselaar, Ingrid M. B. H. van de Laar, Marieke J. H. Baars, Annette Baas, Eelco Dulfer, Apollonia T. J. M. Helderman‐van den Enden, Yvonne Hilhorst‐Hofstee, Robert M. Kauling, Marlies J. E. Kempers, Martijn A. Oudijk, Alessandra Maugeri, Hennie T. Brüggenwirth, Arjan C. Houweling, Serwet Demirdas   +13 more
wiley   +1 more source