Results 51 to 60 of about 5,934 (136)

Atherosclerosis enhances the efficacy of liposome-encapsulated bromocriptine in reducing the incidence of prolactinemia in pituitary tumors

Journal of Nanobiotechnology
Intranasal drug delivery via nanocarriers has long been a research focus for enhancing drug concentration in the brain. However, the strategy of exploiting blood–brain barrier (BBB) alterations in atherosclerotic mouse models to enhance nanoparticle ...
Zhe Zhang, Guangyu Jia, Qi Wang, Yamei Yu, Xiaolong Tang, Heqing Zheng, Xinyu Yang, Yao Xiao, Yangrui Ou, Jingjing Jiang, Hua Guo, Ye Wang, Shiyong Li   +12 more
doaj   +1 more source

Cervicocerebral Atherosclerosis Burden Increases Long‐Term Mortality in Patients With Ischemic Stroke or Transient Ischemic Attack

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The influence of burden of atherosclerosis in the brain supplying arteries on mortality in patients with acute ischemic stroke or transient ischemic attack is poorly known.
Kati Lainelehto, Juha‐Pekka Pienimäki, Sirpa Savilahti, Heini Huhtala, Heikki Numminen, Jukka Putaala   +5 more
doaj   +1 more source

Resolving cognitive heterogeneity in white matter hyperintensities through integrated analyses of microbiome, metabolome, and brain glymphatic function

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Individuals with similar white matter hyperintensities (WMH) burden show heterogeneous cognitive outcomes, yet the biological mechanisms underlying this variability remain incompletely understood. METHODS We integrated 16S rDNA sequencing, untargeted metabolomics, and multi‐modal magnetic resonance imaging (MRI) to comprehensively
Xiaotao Xu, Xia Zhou, Mengwei Zhang, Jingjing Fang, Zhiqing Yan, Xiaoqun Zhu, Yongqiang Yu, Jiajia Zhu   +7 more
wiley   +1 more source

Vessel-Wall Magnetic Resonance Imaging of Intracranial Atherosclerotic Plaque and Ischemic Stroke: A Systematic Review and Meta-Analysis

Frontiers in Neurology, 2018
Introduction: Vessel-wall magnetic resonance imaging (MRI) has been suggested as a valuable tool for assessing intracranial arterial stenosis with additional diagnostic features.
Han Na Lee, Chang-Woo Ryu, Seong Jong Yun   +2 more
doaj   +1 more source

Validación de un laboratorio básico de neurosonología para la detección de estenosis carotídea cervical

Neurología, 2019
Resumen: Introducción: La detección de estenosis arterial cervical e intracraneal es fundamental en el estudio del ictus isquémico, al ser el origen aterotrombótico el más prevalente en nuestro entorno.
C. de la Cruz Cosme, M.S. Dawid Milner, G. Ojeda Burgos, A. Gallardo Tur, M. Márquez Martínez, T. Segura   +5 more
doaj   +1 more source

Anticoagulant or Antithrombotic Therapy After Early Neurological Deterioration in Patients With Branch Atheromatous Disease Receiving Dual Antiplatelet Therapy

International Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Objective We evaluated the effectiveness and safety of adding tirofiban or argatroban after early neurological deterioration (END) in patients with branch atheromatous disease (BAD) receiving dual antiplatelet therapy and compared the outcomes with those of patients who continued dual antiplatelet therapy alone. Methods This retrospective study focused
Xuemin Zhong, Juan Yang, Ronghua Xu, Jian Wang, Nikhat Kaura   +4 more
wiley   +1 more source

Validation of a basic neurosonology laboratory for detecting cervical carotid artery stenosis

Neurología (English Edition), 2019
Introduction: Most of the cases of ischaemic stroke in our setting are of atherothrombotic origin. Detecting intracranial and cervical carotid artery stenosis in patients with ischaemic stroke is therefore essential.
C. de la Cruz Cosme, M.S. Dawid Milner, G. Ojeda Burgos, A. Gallardo Tur, M. Márquez Martínez, T. Segura   +5 more
doaj   +1 more source

Acute (14‐Day) and Subchronic (90‐Day) Toxicity Evaluation of the Dried Fruit Spice Xylopia aethiopica (Dunal) A. Rich. (Annonaceae) in Male and Female Wistar Rats

Journal of Toxicology, Volume 2026, Issue 1, 2026.
Background Xylopia aethiopica (XAE) fruit (Ethiopian pepper) is a culinary spice widely used in African countries. It has numerous biological properties including potent anticancer properties; however, there is a lack of data on its safety, which justifies this study.
Merline Ymele Nguedia, Ornella Bernie Kami Nkuimi, Borelle Mafogang, Herve Herve Abaissou Ngatanko, Dieudonne Njamen, Stephane Zingue, Jasbir Arora (RSS)   +6 more
wiley   +1 more source

Clinical effect analysis of recanalization treatment for acute ischemic stroke with large infarct core caused by intracranial atherosclerotic stenosis and cardiac embolism

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To investigate the short ⁃ term efficacy, long ⁃ term outcome and safety of recanalization treatment in patients with acute ischemic stroke presenting with large infarct core caused by intracranial atherosclerotic stenosis (ICAS) versus ...
ZHU Jin⁃zhao, XIE Wei⁃zheng, ZHANG Jian⁃gang, FENG Guang   +3 more
doaj   +1 more source

C-factor: a summary measure for systemic arterial calcifications

BMC Cardiovascular Disorders, 2021
Background Arterial calcification, the hallmark of arteriosclerosis, has a widespread distribution in the human body with only moderate correlation among sites.
Lieke M. Kuiper, M. Kamran Ikram, Maryam Kavousi, Meike W. Vernooij, M. Arfan Ikram, Daniel Bos   +5 more
doaj   +1 more source