Results 61 to 70 of about 9,913 (190)

Plasma and neuroimaging biomarkers of small vessel disease and Alzheimer's disease in a diverse cohort: MESA

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Little is known about how Alzheimer's disease (AD) plasma biomarkers relate to cerebral small vessel disease (cSVD) neuroimaging biomarkers. METHODS The study involved 251 Wake Forest Multi‐Ethnic Study of Atherosclerosis (MESA) Exam 6 participants with plasma AD biomarkers, magnetic resonance imaging, amyloid positron emission ...
Samuel N. Lockhart, Courtney L. Sutphen, Jordan Tanley, Fernando Gonzalez‐Ortiz, Przemysław R. Kac, Mohamad Habes, Susan R. Heckbert, Nicholas J. Ashton, Michelle M. Mielke, Robert Koeppe, Marc D. Rudolph, Kiran K. Solingapuram Sai, Christopher T. Whitlow, Kevin D. Hiatt, Suzanne Craft, Thomas C. Register, Kathleen M. Hayden, Stephen R. Rapp, Bonnie C. Sachs, Henrik Zetterberg, Kaj Blennow, Thomas K. Karikari, Timothy M. Hughes   +22 more
wiley   +1 more source

Deep learning and high-resolution magnetic resonance vascular wall imaging: current challenges and future perspectives

Frontiers in Neurology
High-resolution magnetic resonance vessel wall imaging (HR-VWI) is an advanced MR imaging technique that can directly visualize intracranial vessel walls and detect subtle pathological changes. HR-VWI can improve diagnostic confidence, help differentiate
Zhiming Cui, Jibo Hu, Huiqing Zhang
doaj   +1 more source

Resolving cognitive heterogeneity in white matter hyperintensities through integrated analyses of microbiome, metabolome, and brain glymphatic function

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Individuals with similar white matter hyperintensities (WMH) burden show heterogeneous cognitive outcomes, yet the biological mechanisms underlying this variability remain incompletely understood. METHODS We integrated 16S rDNA sequencing, untargeted metabolomics, and multi‐modal magnetic resonance imaging (MRI) to comprehensively
Xiaotao Xu, Xia Zhou, Mengwei Zhang, Jingjing Fang, Zhiqing Yan, Xiaoqun Zhu, Yongqiang Yu, Jiajia Zhu   +7 more
wiley   +1 more source

Association of inferior vena cava filter placement for venous thromboembolic disease and a contraindication to anticoagulation with 30-day mortality [PDF]

, 2018
Importance: Despite the absence of data from randomized clinical trials, professional societies recommend inferior vena cava (IVC) filters for patients with venous thromboembolic disease (VTE) and a contraindication to anticoagulation therapy.
Brown, David L, Novak, Eric, Saeed, Mohammed J, Turner, Tyson E   +3 more
core   +1 more source

Efficacy and safety of balloon dilation versus stent implantation in young ischemic stroke patients with symptomatic intracranial artery stenosis

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To compare the efficiency and safety between balloon dilation and stent implantation in young ischemic stroke patients with symptomatic intracranial artery stenosis (ICAS).
ZHANG He, YU Lin⁃jie, ZHANG Xi, LUO Yun, XU Yun, LI Jing⁃wei   +5 more
doaj   +1 more source

Tmax volume can predict clinical type in patients with acute ischemic stroke

Brain and Behavior, 2023
Objective Endovascular therapy (EVT) is performed for acute ischemic stroke (AIS) with large vessel occlusion (LVO), however, the treatment strategies and clinical outcomes differ between cardiac embolism (CE) and intracranial arteriosclerosis‐derived ...
Fumihisa Kishi, Ichiro Nakagawa, Seigo Kimura, Daiji Ogawa, Ryokichi Yagi, Keiichi Yamada, Hirokatsu Taniguchi   +6 more
doaj   +1 more source

Association between homocysteine and white matter hyperintensities in rural‐dwelling Chinese people with asymptomatic intracranial arterial stenosis: A population‐based study

Brain and Behavior, 2021
Purpose Although homocysteine (Hcy) has been proven to be associated with the incidence of white matter hyperintensities (WMH) in patients with stroke, this association remains unclear in participants with asymptomatic intracranial arterial stenosis ...
Xiang Wang, Hao Yin, Xiaokang Ji, Shaowei Sang, Sai Shao, Guangbin Wang, Ming Lv, Fuzhong Xue, Yifeng Du, Qinjian Sun   +9 more
doaj   +1 more source

Anticoagulant or Antithrombotic Therapy After Early Neurological Deterioration in Patients With Branch Atheromatous Disease Receiving Dual Antiplatelet Therapy

International Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Objective We evaluated the effectiveness and safety of adding tirofiban or argatroban after early neurological deterioration (END) in patients with branch atheromatous disease (BAD) receiving dual antiplatelet therapy and compared the outcomes with those of patients who continued dual antiplatelet therapy alone. Methods This retrospective study focused
Xuemin Zhong, Juan Yang, Ronghua Xu, Jian Wang, Nikhat Kaura   +4 more
wiley   +1 more source

Atherosclerosis enhances the efficacy of liposome-encapsulated bromocriptine in reducing the incidence of prolactinemia in pituitary tumors

Journal of Nanobiotechnology
Intranasal drug delivery via nanocarriers has long been a research focus for enhancing drug concentration in the brain. However, the strategy of exploiting blood–brain barrier (BBB) alterations in atherosclerotic mouse models to enhance nanoparticle ...
Zhe Zhang, Guangyu Jia, Qi Wang, Yamei Yu, Xiaolong Tang, Heqing Zheng, Xinyu Yang, Yao Xiao, Yangrui Ou, Jingjing Jiang, Hua Guo, Ye Wang, Shiyong Li   +12 more
doaj   +1 more source

Cervicocerebral Atherosclerosis Burden Increases Long‐Term Mortality in Patients With Ischemic Stroke or Transient Ischemic Attack

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The influence of burden of atherosclerosis in the brain supplying arteries on mortality in patients with acute ischemic stroke or transient ischemic attack is poorly known.
Kati Lainelehto, Juha‐Pekka Pienimäki, Sirpa Savilahti, Heini Huhtala, Heikki Numminen, Jukka Putaala   +5 more
doaj   +1 more source