Results 71 to 80 of about 182,210 (246)

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Paediatric traumatic Brain Injury: The relationship between Intracranial Pressure and Brain Oxygenation [PDF]

, 2009
Introduction: Intracranial pressure (ICP) monitoring is a cornerstone of care for patients with severe traumatic brain injury (TBI). The primary goal of ICP treatment is to preserve brain oxygenation, and since brain oxygenation is usually not measured ...
Rohlwink, Ursula Karin
core   +1 more source

Exploring the relationship between embolic acute stroke distribution and supra-aortic vessel patency: key findings from an in vitro model study

Stroke and Vascular Neurology
Background We investigated differences in intracranial embolus distribution through communicating arteries in relation to supra-aortic vessel (SAV) patency.Methods For this experimental analysis, we created a silicone model of the extracranial and ...
Joaquin Ortega-Quintanilla, Astrid Jeibmann, Walter Heindel, Boris Buerke, Aglae Velasco Gonzalez, Cristina Sauerland, Dennis Görlich, Andreas Faldum, Werner Paulus   +8 more
doaj   +1 more source

Aneurisma micótico abdominal e embolia cerebral associados à endocardite infecciosa em paciente com doença valvar reumática crônica Abdominal mycotic aneurysm and cerebral embolic event associated with infective endocarditis in a patient with chronic rheumatic valvar disease

Arquivos Brasileiros de Cardiologia, 2007
Relatamos o caso de uma menina com doença valvar crônica devido à febre reumática que apresentou endocardite infecciosa e duas complicações: acidente vascular cerebral devido à embolia e aneurisma micótico da artéria mesentérica superior.We report the ...
Bernadete Lourdes Liphaus, Cláudia Goldenstein-Schainberg, Letícia Monteiro Kitamura, Clóvis Artur Almeida Silva   +3 more
doaj   +1 more source

Cerebral Arterial Calcification Is an Imaging Prognostic Marker for Revascularization Treatment of Acute Middle Cerebral Arterial Occlusion [PDF]

Journal of Stroke, 2015
Background and PurposeTo study the significance of intracranial artery calcification as a prognostic marker for acute ischemic stroke patients undergoing revascularization treatment after middle cerebral artery (MCA) trunk occlusion.MethodsPatients with ...
Seong-Joon Lee, Ji Man Hong, Manyong Lee, Kyoon Huh, Jin Wook Choi, Jin Soo Lee   +5 more
doaj   +1 more source

Mobile health interventions to improve adherence to oral anticoagulant treatment: A systematic review and critical analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Non‐adherence to oral anticoagulants (OACs) is associated with significant morbidity and mortality. Mobile health (mHealth) interventions have been used to improve medication adherence across the three phases of initiation, implementation and persistence.
Non Davies, Elin Haf Davies, Dyfrig A. Hughes   +2 more
wiley   +1 more source

Safety of localizing epilepsy monitoring intracranial electroencephalograph electrodes using MRI: radiofrequency-induced heating [PDF]

, 2008
Purpose: To investigate heating during postimplantation localization of intracranial electroencephalograph (EEG) electrodes by MRI. Materials and Methods: A phantom patient with a realistic arrangement of electrodes was used to simulate tissue ...
Lemieux, L., Thornton, J.S., Carmichael, D.W., Rodionov, R., McEvoy, A., Thornton, R., Allen, P.J.   +6 more
core  

Stereo‐electroencephalography–guided responsive neuromodulation: A propensity‐matched cohort study

Epilepsia, EarlyView.
Abstract Objective The optimal pre‐implantation evaluation and surgical targeting strategies for responsive neurostimulation (RNS) in patients with unresectable, drug‐resistant focal epilepsy continue to be debated. Although stereo‐electroencephalography (sEEG) is central to characterizing the seizure‐onset zone, its role in preoperative testing for ...
David Botros, Julian Brown, John D. Rolston, Paul A. House, Amir Arain, Matthew Jensen, Blake Newman, Brian Johnson, Sindhu Richards, Angela Peters, Shervin Rahimpour, Ben Shofty   +11 more
wiley   +1 more source

Temporary brittle bone disease:association with intracranial bleeding [PDF]

, 2013
We report 20 infants aged between 1 month and 6 months found to have subdural bleeding and also multiple unexplained fractures in a pattern similar to that described earlier as temporary brittle bone disease. Child abuse seemed unlikely as a cause of the
Paterson, Colin R., Monk, Elizabeth
core   +1 more source

Patient-Specific Hemodynamic Simulation for Predicting Stroke Laterality in Cardiac Embolism [PDF]

Journal of Stroke
Background and Purpose Cardioembolic sources account for 20%–30% of acute ischemic strokes (AIS), often with high morbidity. Conventional imaging confirms etiology retrospectively but lacks insight into the dynamic behavior of embolic transport. We aimed
Mahbod Issaiy, Diana Zarei, David S. Liebeskind, Pouria Moshayedi   +3 more
doaj   +1 more source