Results 81 to 90 of about 24,592 (238)

Transforming Growth Factor‐Beta Signaling in Cancer: Therapeutic Implications, Challenges, and Pathways to Progress

open access: yesMedComm – Oncology, Volume 4, Issue 3, September 2025.
TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi   +5 more
wiley   +1 more source

Anticoagulation intensity and outcomes among southeast‐Asians with moderate‐to‐severe mitral valve stenosis

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 8, Page 2273-2282, August 2025.
Objective To determine the optimal anticoagulation intensity of warfarin in a South‐East Asian population with moderate‐to‐severe rheumatic mitral stenosis. Methods A multicentre, retrospective study examined patients with rheumatic mitral stenosis who had not undergone valve replacement or repair and required long‐term warfarin therapy at two ...
Punyawee Puchsaka   +6 more
wiley   +1 more source

Evaluation of the Presence of Native Valvular Disease in Patients With Atrial Fibrillation Using the EHRA (Evaluated Heartvalves, Rheumatic, or Artificial) Classification

open access: yesClinical Cardiology, Volume 48, Issue 8, August 2025.
In anticoagulated AF patients, those with native valve involvement (EHRA 2) have a worse prognosis than patients without valve involvement (EHRA 3). The presence of native valvular disease is shown as an independent risk factor for adverse outcomes. ABSTRACT Background Atrial fibrillation (AF) in association with native valvular heart disease (VHD) is ...
Antonio Escolar Conesa   +14 more
wiley   +1 more source

Cerebral embolism caused by tissue adhesive injection for varices of gastric fundus: one case report

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2020
DOI:10.3969/j.issn.1672⁃6731.2020.03 ...
Rong⁃jiao YOU   +3 more
doaj  

microRNAs and Markers of Neutrophil Activation as Predictors of Early Incidental Post-Surgical Pulmonary Embolism in Patients with Intracranial Tumors [PDF]

open access: gold, 2020
Júlia Oto   +12 more
openalex   +1 more source

A multicentre registry of hospitalized patients with acute and chronic heart failure: Study design of the H2‐registry

open access: yesESC Heart Failure, Volume 12, Issue 4, Page 3114-3133, August 2025.
The H2‐Registry: overview, first results and outlook. Abstract Aims Heart failure (HF) is a highly prevalent condition affecting 1–3% of the adult population in Europe. Despite landmark improvements in HF care over the last two decades, hospitalization and mortality rates remain relatively high.
Johannes Leiner   +15 more
wiley   +1 more source

Patchy profile sign in RAPID software: a specific marker for intracranial atherosclerotic stenosis in acute ischemic stroke

open access: yesFrontiers in Neurology
PurposeIdentifying the etiology of acute ischemic stroke (AIS) before endovascular treatment (EVT) is important but challenging. In CT perfusion imaging processed by perfusion software, we observed a phenomenon called patchy profile sign (PPS), that is ...
Lingwen Zhang   +17 more
doaj   +1 more source

Safety and Oncologic Outcomes of Endoscopic Endonasal Transcribriform Approach for Locally Advanced Sinonasal Malignancies

open access: yesHead &Neck, Volume 47, Issue 8, Page 2348-2357, August 2025.
ABSTRACT Introduction The past two decades have seen a paradigm shift in the surgical treatment of sinonasal malignancies, moving from traditional open approaches to minimally invasive endoscopic techniques. Technological advancements have enabled the use of the endoscopic endonasal transcribriform approach (EETA) for tumors involving the anterior ...
Michel Khalaf   +11 more
wiley   +1 more source

Cerebral air embolism associated with cavitary lung lesion in a patient with Ehlers-Danlos syndrome

open access: yesRadiology Case Reports
Pneumocephalus, is a general term describing the presence of air within the intracranial structures. It most commonly occurs due to dural injury, often the sequela of head trauma or surgery.
Joshua Mangerel, MD   +2 more
doaj  

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