Results 81 to 90 of about 156,971 (327)
Advanced Science, EarlyView.This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang +15 more
wiley +1 more source
Effect of Hyperosmolar Solutions on Cerebral Oxygenation and Metabolism
Общая реаниматология, 2008 Objective: to assess the time course of changes in the parameters of cerebral oxygenation and metabolism in the correction of intracranial hypertension with hyperosmolar solutions. Material and methods.
S. S. Petrikov +5 more
doaj +1 more source
Forensic and clinical diagnosis in shaken baby syndrome , between child abuse and iatrogenic abuse [PDF]
, 2017 “Shaken baby syndrome” in child abuse cases is a challenge for pediatrician and forensic experts, often a diagnosis of exclusion, with overwhelming moral and legal implications.
Apostol, Irina +3 more
core +3 more sources
Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes
Advanced Science, EarlyView.Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako +16 more
wiley +1 more source
Advanced Science, EarlyView.Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen +14 more
wiley +1 more source
A Pregnancy Case with Idiopathic Intracranial Hypertension that Improved with Diet
Türk Nöroloji Dergisi, 2009 Idiopathic intracranial hypertension is a syndrome characterized by an increase in intracranial pressure, without hydrocephaly or a mass lesion. It is most commonly encountered in obese adolescent girls, young women, and pregnant women.
Güner Koyuncu Çelik, Mehmet Borazan
doaj
Measurement of Intraspinal Pressure After Spinal Cord Injury: Technical Note from the Injured Spinal Cord Pressure Evaluation Study. [PDF]
, 2016 Intracranial pressure (ICP) is routinely measured in patients with severe traumatic brain injury (TBI). We describe a novel technique that allowed us to monitor intraspinal pressure (ISP) at the injury site in 14 patients who had severe acute traumatic ...
Bell, BA +10 more
core +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Marden–Walker syndrome (MWS; OMIM 248700) is an extremely rare congenital disorder characterized by multiple joint contractures, craniofacial dysmorphism, neurological abnormalities, and multisystem involvement. Although historically diagnosed on clinical grounds, only a few cases have been molecularly confirmed.
Guilherme Sotto Battiston +35 more
wiley +1 more source
Surgical management of intracranial hypertension in rickets-related craniosynostosis
Interdisciplinary NeurosurgeryHypophosphatemic rickets is occasionally associated with craniosynostosis. Delayed diagnosis can result in intracranial hypertension, potentially leading to serious neurological complications.
Alessio Iacoangeli +8 more
doaj +1 more source
Subarachnoid Hemorrhage from Posterior Cerebral Artery Aneurysm during Puerperium – Case Report and Review of Literature [PDF]
, 2012 Subarachnoid hemorrhages (SAH) due to true aneurysms of the Posterior Cerebral Artery (PCA) during puerperium in young and healthy females are extremely rare.
Brawanski, Alexander +4 more
core +1 more source