Results 171 to 180 of about 4,989,210 (357)

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Effect of gravity and microgravity on intracranial pressure

Journal of Physiology, 2017
Justin S. Lawley, L. Petersen, E. Howden, S. Sarma, W. Cornwell, Rong Zhang, L. Whitworth, Michael A. Williams, B. Levine   +8 more
semanticscholar   +1 more source

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

Brain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye, Fei Peng, Chao Pan, Ping Zhang, Xuewei Xie, Zixiao Li, Yingxin Tang, Danyang Chen, Yuanwei Li, Jiawen Wu, Zao Han, Qing Dai, Quansheng Gu, Jizong Zhao, Zhouping Tang   +14 more
wiley   +1 more source

Increased intracranial pressure in NF2‑related schwannomatosis: an underestimated danger with serious consequences. [PDF]

J Neurooncol
Keraudy A, Vincent C, Risoud M, Monfilliette A, Hanafi R, Peyre M, Reyns N, Kalamarides M, Aboukais R.   +8 more
europepmc   +1 more source

Housing Warmth/Coolness and Quietness Correlate With Whole‐Brain Fractional Anisotropy in Healthy Adults

Brain Health, EarlyView.
ABSTRACT Introduction Residential environments have been linked to brain structure, particularly in children, older adults, and clinical populations. However, little is known about how different dimensions of the housing environment relate to brain white matter microstructure in healthy adults, or whether specific environmental factors show stronger ...
Keisuke Kokubun, Kiyotaka Nemoto, Toshiharu Ikaga, Yoshinori Yamakawa   +3 more
wiley   +1 more source

Intracranial pressure management in severe intraventricular hemorrhage: A minireview. [PDF]

World J Crit Care Med
Qiu WS, Chen HD, Yang WJ, Chen MM.
europepmc   +1 more source

Global Trends and Advances in Traumatic Brain Injury

Brain Health, EarlyView.
ABSTRACT Traumatic brain injury (TBI) remains a major global public health challenge, contributing substantially to morbidity and mortality while imposing a significant socioeconomic burden. In recent years, notable progress has been made in understanding TBI pathophysiology, classification, monitoring, and treatment.
Yuan Zhuang, Xixian Liao, Jiyao Jiang, Guoyi Gao   +3 more
wiley   +1 more source

The clinical significance of intracranial pressure waveform analysis in brain-injured patients. [PDF]

Crit Care Sci
Brasil S, Taccone FS.
europepmc   +1 more source

Brain Health Deviation Index: A Comprehensive Brain Health Assessment Biomarker for Predicting Cognitive Decline and Polyvascular Stenosis

Brain Health, EarlyView.
ABSTRACT Assessing and quantifying brain health remains a pressing challenge, despite its importance for overall well‐being. Traditional methods that focus on isolated brain measures often fail to capture the multifaceted nature of brain health and may miss early signs of dysfunction.
Ziyang Liu, Shaodong Ding, Hao Liu, Jing Jing, Jian Cheng, Huaguang Zheng, Jiyang Jiang, Wei Wen, Zhe Zhang, Wanlin Zhu, Shiping Li, Yuesong Pan, Xueli Cai, Yijun Zhou, Chang Liu, Xia Meng, Yilong Wang, Hao Li, Yong Jiang, Haijun Niu, Nicole Kochan, Henry Brodaty, Tiemin Wei, Yubo Fan, Zixiao Li, Perminder S. Sachdev, Tao Liu, Yongjun Wang   +27 more
wiley   +1 more source