Results 51 to 60 of about 1,822,102 (382)
Deep brain stimulation for intractable neuropathic facial pain.
Neurosurgical Focus, 2018 OBJECTIVE Deep brain stimulation (DBS) is a well-established, evidence-based therapy with FDA approval for Parkinson's disease and essential tremor.
Sharona Ben-Haim +2 more
semanticscholar +1 more source
, 2016 Neuromodulation is a new promising treatment for headache disorders. It consists of peripheral nerve neurostimulation and central neurostimulation. © 2016, Touch Briefings.
Silberstein, Stephen
core +2 more sources
Quality of Life Research, 2018 PurposeChronic axial low-back pain is a debilitating disorder that impacts all aspects of an afflicted individual’s life. Effective, durable treatments have historically been elusive.
K. Amirdelfan +15 more
semanticscholar +1 more source
Arthritis Care &Research, EarlyView.Objective Systemic sclerosis (SSc) is a rare autoimmune disease characterized by tissue fibrosis, vasculopathy, and immune dysregulation. Our objectives were to quantify the overall and site‐specific cancer risks in patients with SSc compared to the general population, examine temporal trends in cancer incidence following SSc diagnosis, and explore ...
Jihyun Na +4 more
wiley +1 more source
"Semicut” skill on the cystic duct in laparoscopic cholecystectomy
Frontiers in Surgery, 2023 This study aimed to decrease the incidence of residual stones in the cystic duct and consequently decrease the incidences of intractable pain and the formation of a small gallbladder after laparoscopic cholecystectomy (LC).
Linxun Liu, Zhanxue Zhao, Jinyu Yang
doaj +1 more source
Arthritis Care &Research, Accepted Article.Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla +13 more
wiley +1 more source
NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex
Advanced Science, EarlyView.The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang +8 more
wiley +1 more source
Treatments for spasticity and pain in multiple sclerosis: a systematic review [PDF]
, 2003 Objectives: To identify the drug treatments currently available for the management of spasticity and pain in multiple sclerosis (MS), and to evaluate their clinical and cost-effectiveness.
Beard, S.M., Hunn, A., Wight, J.
core +1 more source
The Clinical Journal of Pain, 2018 Background: Neuropathic pain is one of the common complications after spinal cord injury (SCI), affecting individuals’ quality of life. The molecular mechanism for neuropathic pain after SCI is still unclear.
Yimin Wang +13 more
semanticscholar +1 more source
Advanced Science, EarlyView.Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan +9 more
wiley +1 more source