Results 71 to 80 of about 38,659 (182)

VSED Should Not Be a Pathway to MAiD (Though Both Are Ethically Permissible)

open access: yesBioethics, EarlyView.
ABSTRACT Recent changes in aid in dying laws have led some to argue for a pathway from Voluntarily Stopping Eating and Drinking (VSED) to Medical Aid in Dying (MAiD). Proponents point to the Sontag case as demonstrating the efficacy of the practice. This article first provides an overview of the development of the practice of VSED and MAiD and provides
D. B. Davison
wiley   +1 more source

Mental health aspects and the doctor-patient relationship do matter in the management of refractory chronic pain

open access: yesO Mundo da Saúde
Chronic non-cancer pain (CNCP) is among the clinical conditions that most challenge curative medicine due to its high therapeutic failure rates. In many cases, pain management teams are unable to identify a clear organic cause for the pain condition; in ...
João Paulo Consentino Solano   +3 more
doaj   +1 more source

Infrared Therapy for Chronic Low Back Pain: A Randomized, Controlled Trial

open access: yesPain Research and Management, 2006
OBJECTIVE: The objective of the present study was to assess the degree of pain relief obtained by applying infrared (IR) energy to the low back in patients with chronic, intractable low back pain.
George D Gale, Peter J Rothbart, Ye Li
doaj   +1 more source

Post‐Trial Responsibilities for Participants Implanted With Neurosurgical Devices: A Qualitative Study

open access: yesBioethics, EarlyView.
ABSTRACT The issue of post‐trial responsibility is about what is owed to research participants after a clinical trial ends, who is responsible, and how long this responsibility must endure. Despite two decades of international guidance on this issue, research involving novel high‐risk interventions—such as implantable neurotechnologies—raises ...
Nathan Higgins   +2 more
wiley   +1 more source

Erector spinae plane block for intractable, nonsurgical abdominal pain: a scoping review [PDF]

open access: yesClinical and Experimental Emergency Medicine
Abdominal pain is one of the most common presenting chief complaints in the emergency department. Erector spinae plane block (ESPB) is an ultrasound-guided nerve block with proven effectiveness in treating visceral and somatic abdominal pain. Despite the
Ashley Meyer   +8 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Longitudinal pancreatico-gastrostomy: An effective means of pain control in chronic pancreatitis

open access: yesThe Saudi Journal of Gastroenterology, 2007
Aim: To assess the effectiveness of longitudinal pancreatico-gastrostomy (LPG) in relieving intractable abdominal pain in patients of chronic pancreatitis (CP) with dilated main pancreatic duct (MPD).
Bhattacharjee Prosanta
doaj  

Predictive Factors of Successful Spinal Cord Stimulation in Patients with Chronic Pain: A Retrospective Cohort Study

open access: yesBrain Sciences
Background: Spinal cord stimulation (SCS) is applied for managing chronic intractable pain, but the factors predicting its effectiveness have not been extensively researched.
Yongjae Yoo   +5 more
doaj   +1 more source

The Tragedy of Painless Needs

open access: yesPain Research and Management, 2000
Intractable pain demands the attention of both the patient and the physician. However, modern science and medicine cannot and should not promise the abolition of pain and suffering.
John D Loeser
doaj   +1 more source

Peripheral targets for neuropathic pain

open access: yesBritish Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour   +3 more
wiley   +1 more source

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