Results 61 to 70 of about 1,837,011 (336)

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

open access: yesAdvanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang   +8 more
wiley   +1 more source

A-Type KV Channels in Dorsal Root Ganglion Neurons: Diversity, Function, and Dysfunction [PDF]

open access: yes, 2018
A-type voltage-gated potassium (Kv) channels are major regulators of neuronal excitability that have been mainly characterized in the central nervous system. By contrast, there is a paucity of knowledge about the molecular physiology of these Kv channels
Covarrubias, Manuel   +3 more
core   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

open access: yesAdvanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

OPEN ANTERIOR CORDOTOMY AS A POSSIBLE TECHNIQUE FOR PAIN RELIEF IN CANCER PATIENT: AN EXPERIENCE WITH SEVEN CASES [PDF]

open access: yesActa Medica Iranica, 1996
Seven patients who had intractable pain of the pelvis and lower extremities were scheduled for cordotomy of the spinothalamic tracts after preliminary investigations.
Sheikhrezai   +4 more
doaj   +1 more source

Relief of interstitial cystitis/bladder pain syndrome by spinal cord stimulation

open access: yesInterdisciplinary Neurosurgery, 2022
Interstitial cystitis/bladder pain syndrome is a chronic, visceral pain syndrome that affects one in every twenty women. Sacral roots stimulation is successfully used to mitigate pain and urinary symptoms when non surgical treatments are ineffective.
Nazih Moufarrij, Miranda Huebner
doaj   +1 more source

Ultrasonic distance detection for a closed-loop spinal cord stimulation system [PDF]

open access: yes, 1997
When stimulating the spinal cord at a constant strength, the current density in the spinal cord and thus the effects on chronic, intractable pain and vascular insufficiency will change with body position, due to the varying separation of the spinal cord ...
Bergveld, P.   +3 more
core   +2 more sources

Engineering Ultrasound Contrast Agents for Targeted Therapeutics: A Theranostic Approach to Drug Delivery, Gene Therapy, and Immunomodulation

open access: yesAdvanced NanoBiomed Research, EarlyView.
Ultrasound contrast agents, including microbubbles and nanobubbles, transform imaging and targeted therapy through precise engineering of size, shell composition, and surface properties. This review explores how these innovations enable tissue‐specific delivery, enhance therapeutic efficacy, and extend applications from vascular imaging to tumor ...
Ashkan Seza   +2 more
wiley   +1 more source

Psychosurgery [PDF]

open access: yes, 1958
The following is another chapter of the revised Medico-Moral Problems book of Father Gerald Kelly, S.J., being published by The Catholic Hospital Association.
Kelly, Gerald
core   +1 more source

Risk factors for relapse in ANCA‐associated vasculitis among patients with relapse after induction of remission with rituximab

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To determine risk factors for relapse of ANCA‐associated vasculitis (AAV) after re‐induction of remission with rituximab and discontinuation of maintenance therapy. Methods This is a post‐hoc analysis of the RITAZAREM clinical trial. Patients 15 years or older with AAV and a positive test for anti‐proteinase‐3 (PR3‐) or anti‐myeloperoxidase ...
Ellen Romich   +10 more
wiley   +1 more source

Ultrasound-guided percutaneous laser cervical discectomy for intractable hiccups: A rare case report

open access: yesHeliyon, 2023
Background: Intractable hiccups serve no physiological purpose, but significantly reduce the quality of life. There are a variety of medications suggested for the treatment of persistent or intractable hiccups.
Jiahui Ma   +6 more
doaj   +1 more source

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