Results 1 to 10 of about 13,957 (152)

Risk of the Watch-and-Wait Concept in Surgical Treatment of Intraductal Papillary Mucinous Neoplasm.

JAMA Surgery, 2021
Importance The natural history of intraductal papillary mucinous neoplasms (IPMNs) remains uncertain. The inconsistencies among published guidelines preclude accurate decision-making.
C. Tjaden, M. Sandini, A. Mihaljevic, J. Kaiser, E. Khristenko, P. Mayer, U. Hinz, M. Gaida, C. Berchtold, M. Diener, Martin Schneider, A. Mehrabi, B. Müller-Stich, O. Strobel, T. Hackert, M. Büchler   +15 more
semanticscholar   +1 more source

Lipid metabolism in pancreatic cancer: emerging roles and potential targets

Cancer Communications, Volume 42, Issue 12, Page 1234-1256, December 2022., 2022
Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin, Ruiyuan Xu, Jianlu Song, Rexiati Ruze, Yuan Chen, Chengcheng Wang, Qiang Xu   +6 more
wiley   +1 more source

Role of circulating exosomal biomarkers and their diagnostic accuracy in pancreatic cancer

JGH Open, Volume 7, Issue 1, Page 30-39, January 2023., 2023
This systematic review aims to evaluate the current literature involving pancreatic cancer patient groups in search of highly accurate exosomal biomarkers. We reviewed 9 studies which involved 565 participants (331 PC and 234 controls). The mRNA panel (ARG1, CD63, CK18, Erbb3, GAPDH, H3F3A, KRAS, and ODC1) and GPC1 reported the highest performing ...
Menazir Sha, Basir Kunduzi, Saied Froghi, Alberto Quaglia, Brian Davidson, Giuseppe K Fusai   +5 more
wiley   +1 more source

The impact of race/ethnicity on pancreaticoduodenectomy outcomes for pancreatic cancer

Journal of Surgical Oncology, Volume 127, Issue 1, Page 99-108, January 2023., 2023
Abstract Purpose To investigate the impact of race/ethnicity on surgical outcomes following pancreaticoduodenectomy for pancreatic cancer. Methods A retrospective review of patients undergoing pancreaticoduodenectomy for adenocarcinoma in the National Surgical Quality Improvement Program (NSQIP) database from 2014 to 2019.
Yahya Alwatari, Catalina M. Mosquera, Jad Khoraki, Salem Rustom, Natalie Wall, Athanasios E. Sevdalis, Weston Stover, Jose G. Trevino, Brian Kaplan   +8 more
wiley   +1 more source

CT-Based Radiomics Analysis to Predict Malignancy in Patients with Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas

Cancers, 2020
Simple Summary The management of intraductal papillary mucinous neoplasms of the pancreas (IPMN) remains controversial due to the relatively high rate of unnecessary surgery for low grade dysplasia (LGD) despite the last international recommendations ...
David Tobaly, João Santinha, R. Sartoris, M. Dioguardi Burgio, C. Matos, J. Cros, A. Couvelard, V. Rebours, A. Sauvanet, M. Ronot, N. Papanikolaou, V. Vilgrain   +11 more
semanticscholar   +1 more source

Development of extrahepatic bile ducts and mechanisms of tumorigenesis: Lessons from mouse models

Pathology International, Volume 72, Issue 12, Page 589-605, December 2022., 2022
Abstract The biliary system is a highly branched tubular network consisting of intrahepatic bile ducts (IHBDs) and extrahepatic bile ducts (EHBDs). IHBDs are derived from hepatic progenitor cells, while EHBDs originate directly from the endoderm through a separate branching morphogenetic process.
Hiroyuki Tomita, Akira Hara
wiley   +1 more source

Neural Transformers for Intraductal Papillary Mucosal Neoplasms (IPMN) Classification in MRI images [PDF]

, 2022
Early detection of precancerous cysts or neoplasms, i.e., Intraductal Papillary Mucosal Neoplasms (IPMN), in pancreas is a challenging and complex task, and it may lead to a more favourable outcome. Once detected, grading IPMNs accurately is also necessary, since low-risk IPMNs can be under surveillance program, while high-risk IPMNs have to be ...
arxiv   +1 more source

Pathways of Progression From Intraductal Papillary Mucinous Neoplasm to Pancreatic Ductal Adenocarcinoma Based on Molecular Features.

Gastroenterology, 2019
BACKGROUND & AIMS Intraductal papillary mucinous neoplasms (IPMNs) are regarded as precursors of pancreatic ductal adenocarcinomas (PDAs), but little is known about the mechanism of progression. This makes it challenging to assess cancer risk in patients
Y. Omori, Y. Ono, M. Tanino, H. Karasaki, H. Yamaguchi, T. Furukawa, Katsuro Enomoto, J. Ueda, Atsuko Sumi, Jin Katayama, Miho Muraki, Kenzui Taniue, Kuniyuki Takahashi, Y. Ambo, T. Shinohara, H. Nishihara, J. Sasajima, H. Maguchi, Y. Mizukami, T. Okumura, S. Tanaka   +20 more
semanticscholar   +1 more source

Magnetic wire active microrheology of human respiratory mucus [PDF]

Soft Matter, 2021,17, 7585-7595, 2021
Mucus is a viscoelastic gel secreted by the pulmonary epithelium in the tracheobronchial region of the lungs. The coordinated beating of cilia moves mucus upwards towards pharynx, removing inhaled pathogens and particles from the airways. The efficacy of this clearance mechanism depends primarily on the rheological properties of mucus.
arxiv   +1 more source

S6 ribosomal protein phosphorylation is associated with malignancy of intraductal papillary mucinous neoplasm of the pancreas

Annals of Gastroenterological Surgery, 2020
Glucose metabolism of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas is unclear. S6 ribosomal protein (S6) phosphorylation is involved not only in controlling cell growth but also in glucose metabolism in cancer.
T. Hirashita, Y. Hirashita, Y. Iwashita, Y. Endo, M. Kiyonaga, S. Matsumoto, N. Hijiya, M. Moriyama, K. Murakami, M. Inomata   +9 more
semanticscholar   +1 more source