Letter to the Editor and Comments on: Intravital dynamic and correlative imaging reveals diffusion-dominated canalicular and flow-augmented ductular bile flux [PDF]
Bile, the central metabolic product of the liver, is secreted by hepatocytes into bile canaliculi (BC), tubular subcellular structures of 0.5-2 $\mu$m diameter which are formed by the apical membranes of juxtaposed hepatocytes. BC interconnect to build a highly ramified 3D network that collects and transports bile towards larger interlobular bile ducts
arxiv
Malignant potential of intrahepatic biliary papillomatosis: a case report and review of the literature [PDF]
BACKGROUND: Biliary papillomatosis (BP) is a rare disease entity with a strong malignant potential. It is characterized by multiple papillary adenomas involving both the intrahepatic and extrahepatic biliary tree.
Athanasios Marinis+26 more
core +3 more sources
Endoscopic intraductal radiofrequency ablation (ID‐RFA) can curatively treat residual intraductal lesions after endoscopic papillectomy. This study aimed to verify the tissue invasiveness of ID‐RFA using a novel RF generator and to explore its appropriate settings in an animal experiment, followed by a small clinical study.
Kenjiro Yamamoto+12 more
wiley +1 more source
Active Learning-Based Multistage Sequential Decision-Making Model with Application on Common Bile Duct Stone Evaluation [PDF]
Multistage sequential decision-making scenarios are commonly seen in the healthcare diagnosis process. In this paper, an active learning-based method is developed to actively collect only the necessary patient data in a sequential manner. There are two novelties in the proposed method.
arxiv
ABSTRACT Background and Aim A novel 11‐Fr digital cholangioscope (eyeMAX) has recently become available. However, a prospective comparative study of the diagnostic yield of the eyeMAX and of a conventional cholangioscope (SpyGlass DS II) has not been reported.
Takeshi Ogura+13 more
wiley +1 more source
Microbiome-derived bile acids contribute to elevated antigenic response and bone erosion in rheumatoid arthritis [PDF]
Rheumatoid arthritis (RA) is a chronic, disabling and incurable autoimmune disease. It has been widely recognized that gut microbial dysbiosis is an important contributor to the pathogenesis of RA, although distinct alterations in microbiota have been associated with this disease.
arxiv
Partial pancreatic resection along the embryological fusion plane — no longer a fantasy [PDF]
Background: The embryological connection between the dorsal and ventral pancreatic regions divides the pancreas into two segments. This anatomical dependence allows segmental pancreatic resection through the embryological fusion plane (EFP).
Hać, S.+3 more
core +2 more sources
Role of Endoscopy in Clinical Management of Intraductal Papillary Mucinous Neoplasms
ABSTRACT Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is a well‐recognized precursor of pancreatic carcinoma. Along with cross‐sectional abdominal imaging tests, endoscopic examinations remain the cornerstone in the diagnosis of pancreatic cysts, early detection of IPMN‐derived carcinomas, and risk stratification of patients with ...
Tsuyoshi Hamada+4 more
wiley +1 more source
Cholangiocarcinoma: New insights [PDF]
Cholangiocarcinoma is a malignant neoplasm originating from biliary epithelial cells. The incidence and mortality of this cancer are rising in the world. Currently, cholangiocarcinoma is accepted as a stem cell disease with many risk factors.
Göral, Vedat
core +1 more source
Recent advancements in image‐enhanced endoscopy in the pancreatobiliary field
Abstract Image‐enhanced endoscopy (IEE) has advanced gastrointestinal disease diagnosis and treatment. Traditional white‐light imaging has limitations in detecting all gastrointestinal diseases, prompting the development of IEE. In this review, we explore the utility of IEE, including texture and color enhancement imaging and red dichromatic imaging ...
Haruka Toyonaga+9 more
wiley +1 more source