Results 111 to 120 of about 59,257 (200)

Exfoliative cytology as a tool in the preinvasive anal lesions diagnosis

Medisur
The anal cancer increase in high-risk populations stimulates the implementation of protocols to carry out early diagnosis, as well as the monitoring of high-grade anal intraepithelial neoplasia as a precursor lesion.
Javier Martínez Navarro
doaj  

Triage and care for women with symptoms or diagnosis of pregnancy loss between 14 + 0 and 21 + 6 weeks' gestation

International Journal of Gynecology &Obstetrics, Volume 172, Issue 1, Page 25-50, January 2026.
Abstract Mid‐trimester pregnancy loss (MTL), defined as a pregnancy loss occurring between 14 + 0 and 21 + 6 weeks of gestation, causes significant physical and emotional distress to women and presents clinical challenges to healthcare professionals. It is acknowledged that in low‐resource settings, this guideline might be applicable to births up to 28 
Caroline E. Fox, Rosinder Kaur, Kugajeevan Vigneswaran, Rachel Small, Jenny Carter, Keelin O'Donoghue, Alexander E. P. Heazell, Anna L. David, Nigel Simpson, Angharad Care, Lisa Starrs, Andrew Shennan, Catalina María Valencia González, Priya Soma‐Pillay, Leah Fitzsimmons, Adam J. Devall, Arri Coomarasamy, Mid‐trimester Pregnancy Loss Guideline Consensus Panel, Owen Arthurs, Ruth Bender‐Atik, Phil Bennett, Kirstien Boelaert, Elizabeth Bonney, Leanna Brace, Naomi Carlisle, Davide Casagrandi, Manju Chandiramani, Carolyn Chiswick, Alexandra Emms, Stella Fielder, James Goadsby, Laura Goodfellow, Jim Gray, Jemma Johns, Emma Kirk, Will Lester, Sophie Mackay, Maria Memtsa, Katie Morris, Sunbal Mukhtar, Naimah Raza, Rita Sarquis, Neil Sebire, Lucy Smith, Lucy Spencer, Amos Tetteh, Natalie Woodhead   +46 more
wiley   +1 more source

Assessment of Vulvar Intraepithelial Neoplasia (VIN) Grades Based on Dermoscopic Features: A Diagnostic Study

, 2023
Vincenzo De Giorgi, Elisabetta Magnaterra, Biancamaria Zuccaro, Manfredi Magliulo, Vincenza Maio, Angela Mucilli, Federico Venturi, Ignazio Stanganelli, Daniela Massi   +8 more
openalex   +2 more sources

USP28 Promotes Osimertinib Resistance in H1975 NSCLC Cells by Deubiquitinating and Stabilizing SIRT1

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 1, January 2026.
ABSTRACT Osimertinib (OSI) resistance in non‐small cell lung cancer (NSCLC) remains a significant challenge. This report explored the precise role of USP28 on OSI resistance in NSCLC and identified a functional downstream effector. OSI‐resistant H1975 cells (H1975/OSI) were established by long‐term OSI exposure.
Hu‐Sen Fan, Xiu‐Mei Li, Jia‐Qi Gu, Hai‐Feng Wang, Zhen‐Jiang Zhang   +4 more
wiley   +1 more source

Inhibition of Pancreatic Intraepithelial Neoplasia Progression to Carcinoma by Nitric Oxide-Releasing Aspirin in p48Cre/+-LSL-KrasG12D/+ Mice

, 2012
Chinthalapally V. Rao, Altaf Mohammed, Naveena B. Janakiram, Qian Li, Rebekah L. Ritchie, Stan Lightfoot, Awasthi Vibhudutta, Vernon E. Steele   +7 more
openalex   +1 more source

Pathology of a Canine Model of Localized Prostate Carcinoma

The Prostate, Volume 86, Issue 1, Page 65-83, January 2026.
ABSTRACT Background Dogs spontaneously develop prostate carcinoma (PC) and share prostate gland anatomy, physiology, and size to men. Over the last 15 years, we have developed and refined a canine model of focal PC to evaluate therapeutic‐diagnostic (theranostic) interventions.
Nathan K. Hoggard, Felipe M. Berg, Marlon R. Szczepaniak, Xinning Wang, Noriko Kantake, Gopalakrishnan Ramamurthy, Li Gong, Eric T. Hostnik, Krishan Kumar, Arijit Ghosh, Dong Luo, Michael V. Knopp, Jill M. Keller, Evan T. Keller, Agata A. Exner, James P. Basilion, Michael F. Tweedle, Thomas J. Rosol   +17 more
wiley   +1 more source

Efficacy of Magnifying Endoscopy with Narrow-Band Imaging in the Diagnosis of Early Gastric Cancer and Gastric Intraepithelial Neoplasia [PDF]

Yanan Zhu, Kejian Wu, Fang Yu Wang
openalex   +1 more source

Negative margins and negative HPV tests after large loop excision of the transformation zone: A nationwide historical cohort study

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 1, Page 186-194, January 2026.
Women aged 50 years and older treated with LLETZ face a higher risk of inadequate treatment. Moreover, our findings highlight the need for standardized reporting of missing follow‐up records to improve monitoring of quality indicators. Abstract Introduction Adequate treatment of cervical precancer, defined as negative margins and a negative HPV test ...
Ane‐Kersti Skaarup Knudsen, Tina Hovgaard Randrup, Ulrik Schiøler Kesmodel, Berit Bargum Booth, Line Winther Gustafson, Therese Koops Grønborg, Anne Hammer   +6 more
wiley   +1 more source

A Combinatorial Effect of Immune Checkpoint Inhibitors and CD40 Agonistic Antibody in Murine Pancreatic Cancer Model

Cancer Science, Volume 117, Issue 1, Page 8-18, January 2026.
We established and extensively analyzed an organoid‐based mouse model that closely mimics human pancreatic ductal adenocarcinoma. Monotherapy with an immune checkpoint inhibitor cocktail or a CD40 agonist antibody showed minimal efficacy. However, combining both reagents produced a strong synergistic effect by enhancing anti‐tumor immunity.
Juri Ichikawa, Hiroshi Okuda, Kuniyuki Kawano, Shingo Kato, Shinya Sato, Ryo Kuroishikawa, Daisuke Kurotaki, Wataru Kawase, Haruka Yoshida, Yukihiko Hiroshima, Itaru Endo, Shin Maeda, Tomohiko Tamura   +12 more
wiley   +1 more source

The relative risk of noncervical high‐risk human papillomavirus‐related (pre)malignancies after recurrent cervical intraepithelial neoplasia grade 3: A population‐based study [PDF]

, 2019
Diede Loopik, Renée M.F. Ebisch, Joanna IntHout, Willem J. G. Melchers, Leon F.A.G. Massuger, Ruud L.M. Bekkers, Albert G. Siebers   +6 more
openalex   +1 more source