Results 121 to 130 of about 61,892 (264)

Vaginal intraepithelial neoplasia: a therapeutical dilemma.

, 2013
Vaginal intraepithelial neoplasia (VaIN) represents a rare and asymptomatic pre-neoplastic lesion. Its natural history and potential evolution into invasive cancer are uncertain.
ASSORGI, CHIARA, CATALANO, ANGELICA, F. Sopracordevole, DE SANCTIS, Vitaliana, MATTEUCCI, ELEONORA, MILAZZO, GIUSI NATALIA, RICCIARDI, ENZO, FREGA, Antonio, LOMBARDI, DANILA, MOSCARINI, Massimo   +9 more
core  

Biomarker expression in cervical intraepithelial neoplasia: potential progression predictive factors for low-grade lesions

, 2011
The aim of this study was to reveal whether 3 biomarkers (p16INK4a, ProEx C, and human papilloma virus DNA) are useful in the diagnosis of cervical intraepithelial neoplasia and whether they could predict disease progression of cervical intraepithelial ...
10127186, Inoue, Masaki, 20075, 20086, Ozaki, Satoru, Zen, Yoh, 90377416, 46095   +7 more
core   +2 more sources

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

Prostatic intraepithelial neoplasia- the story evolves

, 2016
Prostatic intraepithelial neoplasia is preneoplastic lesion described from early of this 20th century. PIN includes a spectrum of features ranging from low grade to high grade neoplasia. The studies are focused on their influence to predict the occurence
SV Pradhan, P Sharan
core   +2 more sources

HPV vaccine against anal HPV infection and anal intraepithelial neoplasia.

, 2011
BACKGROUND: The rate of anal cancer is increasing among both women and men, particularly men who have sex with men. Caused by infection with human papillomavirus (HPV), primarily HPV type 16 or 18, anal cancer is preceded by high-grade anal ...
Palefsky, Joel M, Giuliano, Anna R, Guris, Dalya, Goldstone, Stephen, Ferris, Daron G, Vuocolo, Scott, Garner, Elizabeth I. O, Moreira Júnior, Edson Duarte, Radley, David, Marshall, J. Brooke, Haupt, Richard M, Aranda, Carlos, Jessen, Heiko, Hillman, Richard J, Stoler, Mark H, Coutlee, Francois   +15 more
core   +2 more sources

The Varying Faces of Vulvar Neoplasia

Indian Dermatology Online Journal
Vulvar neoplasia is on the rise and patients often present to dermatologists with lesions of varying morphology associated with pruritus, burning sensation, or pain.
Kavitha Athota, Smitha S. Prabhu, Niranjana Gopinathan   +2 more
doaj   +1 more source

Bile‐Derived Exosomal miR‐196a/‐196b as Diagnostic Biomarkers Associated With Tumor Progression in Biliary Tract Cancer

Cancer Science, EarlyView.
Bile‐derived exosomal miR‐196a and miR‐196b are identified as novel biomarkers for biliary tract cancer. Serum miR‐196a levels are significantly elevated in advanced disease with metastasis, while both miRNAs contribute to tumor progression by promoting cancer cell proliferation and invasion.
Naotaka Kugiyama, Katsuya Nagaoka, Takehisa Watanabe, Michihiro Yoshida, Tadashi Toyohara, Cheng Pan, Kenyu Hashimoto, Fumiya Otsuka, Shinya Ushijima, Yukiko Uramoto, Hajime Iwasaki, Motohiro Yoshinari, Shunpei Hashigo, Kazuki Hayashi, Itaru Naitoh, Fumihiro Okumura, Hiromu Kondo, Kaiki Anbe, Hiromitsu Hayashi, Yoshihiro Komohara, Yasuhito Tanaka   +20 more
wiley   +1 more source

HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann, Ulrike Wieland, Steffi Silling, Frank Oellig, David Chromy, Julia Hyun, Thilo Gambichler, Alexander Kreuter   +7 more
wiley   +1 more source

Correction of cyto-biochemical process disorders of cervical mucosa with cervical intraepithelial neoplasia [PDF]

РМЖ. Мать и дитя, 2018
Correction of cyto-biochemical process disorders of cervical mucosa with cervical intraepithelial neoplasia I.O. Borovikov, E.E. Gerasimenko, H.I.
Borovikov I.O., E.E. Gerasimenko, H.I. Gorring   +2 more
doaj  

The emerging role of the Hippo signaling pathway in interorgan crosstalk

The FEBS Journal, EarlyView.
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song, Chaerin Lee, Eek‐hoon Jho   +2 more
wiley   +1 more source