Results 151 to 160 of about 61,892 (264)

GATA3 Inhibits the Expression of Viral E6/E7 Genes, and Its Expression Is Compromised During HPV‐Mediated Cervical Carcinogenesis

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT High‐risk human papillomaviruses (HPV) are the main etiological agents of cervical cancer. The viral early promoter regulates the expression of E6/E7 oncoproteins, and its transcriptional activity is positively or negatively regulated by host transcription factors (TFs) that are able to bind to the viral long control region (LCR).
Valéria Talpe‐Nunes, Aline Lopes Ribeiro, Rafaella Almeida Nunes, João Simão Sobrinho, Amanda Schiersner Caodaglio, Rossana Veronica Mendonza Lopez, Thais Rocha, Maria Luiza Nogueira Dias Genta, Konstanze Schichl, Ademola Aiyenuro, John Doorbar, Laura Sichero   +11 more
wiley   +1 more source

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

Medicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca, Mariana Feijó, Cátia V. Vaz, Bruno J. Pereira, Sandra Laurentino, Ana Palmeira‐de‐Oliveira, Sílvia Socorro   +6 more
wiley   +1 more source

Impact of Male Human Papillomavirus (HPV) Vaccination on HPV Infection and HPV‐Related Diseases: A Systematic Review

Reviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide and is responsible for anogenital warts and several cancers. Although the effectiveness of female HPV vaccination has been well established since its introduction in 2006, no systematic review has specifically evaluated the impact of male vaccination ...
Anna Beltrame, Racheal S. Dube Mandishora, Wei (Vivian) Wang, Wenyi Fan, Mary Katherine Haver, Anna R. Giuliano   +5 more
wiley   +1 more source

Predictive factors for the absence of high‐grade intraepithelial lesions in LLETZ specimens following a prior histological diagnosis

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 7, Page 1240-1246, July 2026.
About 9.4% of patients with biopsy‐proven high‐grade cervical lesions had ultimately no high‐grade lesion (HGIL) in the excision specimen. The probability of the absence of HGIL was significantly increased in patients with a small lesion, with minor changes or normal colposcopy, and in those with normal cytology or minor abnormalities.
Sophia Assirlikian, Julien Mancini, Charles‐André Philip, Geoffroy Canlorbe, Henri Azaïs, Eva Fuss‐Blanco, Lise Lecointre, Karine Le Bail Carval, Dave Nkounawa, Andriniaina Ravelojaona, Xavier Carcopino   +10 more
wiley   +1 more source

The Australian Penile Cancer Clinical Registry: a comprehensive national approach to data collection

BJU International, Volume 138, Issue S2, Page S42-S50, July 2026.
Background Penile cancer is a rare malignancy, with an Australian incidence of 0.6 in 100 000 men, with a wide range of clinical presentations, from localised, curable tumours to aggressive forms with high morbidity and mortality. Epidemiological data and management guidelines for penile cancer in Australia are limited.
Henry Y.C. Pan, David Homewood, Harrison Lucas, Brendan Dittmer, Jiasian Teh, Jonathan S. O'Brien, Jianliang Liu, Ben Tran, Justin Chee, James A. Churchill, Nathan Lawrentschuk, Niall M. Corcoran   +11 more
wiley   +1 more source

Detection of HPV DNA in Cervical Intraepithelial Neoplasia Using In Situ Hybridization. [PDF]

J Clin Med
Przybylski M, Millert-Kalińska S, Pruski D, de Mezer M, Krzyżaniak M, Jach R, Żurawski J, Kurzawa P.   +7 more
europepmc   +1 more source

Relationship Between PTBP1 and Pancreatic Cancer Based on microRNA and Behavior During TYMS‐Mediated Carcinogenesis

Cancer Science, Volume 117, Issue 7, Page 1828-1840, July 2026.
Corresponding Author and colleagues identify a pancreas‐enriched microRNA, miR‐216b‐5p, that suppresses PTBP1 and its downstream effector TYMS. Their findings reveal a novel miR‐216b‐5p/PTBP1/TYMS regulatory axis driving pancreatic cancer progression and establish PTBP1 as a central molecular regulator of tumor biology beyond its metabolic role ...
Shigenori Suzuki, Hiroaki Hase, Yosuke Inomata, Jun Arima, Kentaro Jingushi, Atsushi Tomioka, Nao Kawaguchi, Hiroki Hamamoto, Ryo Tanaka, Yoshiro Imai, Mitsuhiro Asakuma, Tomohito Tanaka, Kazutake Tsujikawa, Kohei Taniguchi, Sang‐Woong Lee   +14 more
wiley   +1 more source

Response to progestin-based therapy in endometrial intraepithelial neoplasia: An exploratory biomarker study. [PDF]

Gynecol Oncol Rep
Seay K, Hare M, Cao J, Katcher A, Akerman M, Beyaz S, Goldberg GL, Frimer M.   +7 more
europepmc   +1 more source

Prognostic impact of anal cancer morphology on survival and local recurrence: A 20‐year regional cohort study

Colorectal Disease, Volume 28, Issue 7, July 2026.
Abstract Aim The relationship between macroscopic tumour morphology and clinical outcomes has previously been demonstrated for malignant melanoma and gastric cancers, but not for anal squamous cell cancer (ASCC). This study investigated the effect of the morphology of ASCC on oncological outcomes.
Alwin Puthiyakunnel Saji, Thomas Rackley, James Horwood, Rachel Hargest   +3 more
wiley   +1 more source

Cost‐effectiveness analysis of human papillomavirus (HPV) genotyping strategies for management of HPV‐positive women in cervical cancer screening

International Journal of Cancer, Volume 158, Issue 12, Page 3141-3151, 15 June 2026.
What's new? Persistent infection with high‐risk human papillomavirus (HPV) causes most invasive cervical cancer cases, leading many countries to transition from cytology to primary HPV‐based screening. Despite the benefits, HPV‐based screening may also lead to unnecessary procedures, psychological burden, and strain on healthcare systems.
Kelsi R. Kroon, Johannes A. Bogaards, Johannes Berkhof   +2 more
wiley   +1 more source