Results 111 to 120 of about 130,124 (257)

Penile intraepithelial neoplasia: Results of photodynarnic therapy

, 2006
Failure of response to treatment or recurrent disease is often noted in patients with penile intraepithelial neoplasia. Photodynamic therapy has recently been added to the list of treatment modalities used for this diagnosis. Our primary objective was to
Lowhagen, Gun-Britt, Forslund, Ola, Ternesten Bratel, Annika, Wennberg, Ann-Marie, Stenquist, Bo, Paoli, John   +5 more
core   +1 more source

Active surveillance of cervical intraepithelial neoplasia and adverse pregnancy outcomes: A register‐based cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Active surveillance for cervical intraepithelial neoplasia grade 2 is not associated with increased risks of adverse pregnancy outcomes compared to large loop excision of the transformation zone. Abstract Introduction Previous studies have suggested that human papillomavirus (HPV) and HPV‐related disease may be associated with increased risk of adverse
Kirstine Kold Katholm, Lotte Krog Eriksen, Kathrine Dyhr Lycke, Ninna Lund Larsen, Iben Sundtoft, Tina Hovgaard Randrup, Anne Hammer   +6 more
wiley   +1 more source

Use of topical imiquimod in the treatment of VIN: a case report and review of the literature

International Journal of Women's Dermatology, 2016
Vulvar intraepithelial neoplasia (VIN) is a premalignant disease of the vulvar squamous epithelium. Standard treatment for VIN lesions is surgical excision.
Chelsea Grimes, BS, MS, Cheri Cunningham, BS, Michael Lee, MD, Andrea Murina, MD   +3 more
doaj   +1 more source

Women's experiences, responses, and coping strategies when testing positive for human papillomavirus in cervical cancer screening: A qualitative study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
This study demonstrates that women's experiences following an hrHPV diagnosis within cervical screening extend beyond individual reactions to medical information, encompassing complex psychological, social, and cultural dimensions that influence how women interpret and manage the diagnosis.
Joan Hansen, Beth J. Maclin, Birgitte Folmann, Jane Ege Møller, Ane Kersti Skaarup Knudsen, Vibeke Raaby, Anne Hammer   +6 more
wiley   +1 more source

Expression of the stem cell markers NANOG and SOX2 in the cervical squamous carcinogenesis

Radiology and Oncology
The aim of the present study was to assess a diagnostic potential of stem cell markers NANOG and SOX2 for classifying cervical squamous intraepithelial lesions (SILs)/cervical intraepithelial neoplasia (CIN).
Koren Miha, Zlajpah Margareta, Poljak Mario, Komlos Kristina Fujs, Flezar Margareta Strojan   +4 more
doaj   +1 more source

Treatment of anal intraepithelial neoplasia

Journal of British Surgery, 1994
Abstract The natural history and malignant potential of anal intraepithelial neoplasia (AIN) remain uncertain, making management decisions about such lesions difficult. The management of 70 patients with AIN is described. The majority of lesions encountered were low grade (AIN I and II; 43 of 70) and required no treatment, but eight ...
J H, Scholefield, O A, Ogunbiyi, J H, Smith, K, Rogers, F, Sharp   +4 more
openaire   +2 more sources

Silicon dioxide vaginal gel and short‐term high‐risk human papillomavirus DNA detectability: A randomized controlled trial

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In an independent randomized trial of 242 women with PCR‐confirmed hrHPV infection, 3 months of silicon dioxide‐based vaginal gel did not improve hrHPV DNA non‐detectability compared with observation alone (18% vs. 21%). Patient‐reported adverse events were more frequent with gel (32% vs. 2%), and overall patient satisfaction was lower.
Julia M. Hecken, Clemens B. Tempfer, Katrin Klaus, Jan Scheich, Günther A. Rezniczek   +4 more
wiley   +1 more source

Delivery mode and maternal health conditions before and after childbirth: A population‐based cohort study from Estonia

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Cesarean section is associated with higher rates of chronic health conditions and pregnancy‐related complications, whereas vaginal delivery is more commonly linked to pelvic floor and perineal complications. These findings emphasize the need for individualized decision‐making and thorough counseling about the risks and benefits of each delivery method.
Katrin Täär, Helle Karro, Merli Saare, Reedik Mägi, Estonian Biobank Research Team, Andres Metspalu, Lili Milani, Tõnu Esko, Mait Metspalu, Mari Nelis, Georgi Hudjashov, Andres Salumets, Triin Laisk, Maire Peters   +13 more
wiley   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann, Ulrike Wieland, Steffi Silling, Frank Oellig, David Chromy, Julia Hyun, Thilo Gambichler, Alexander Kreuter   +7 more
wiley   +1 more source