Results 51 to 60 of about 99,638 (285)

Public health approach to prevent cervical cancer in HIV-infected women in Kenya : issues to consider in the design of prevention programs [PDF]

open access: yes, 2017
Women living with HIV in Africa are at increased risk to be co-infected with Human Papilloma Virus (HPV), persistent high risk (HR) HPV infection and bacterial vaginosis (BV), which compounds HPV persistence, thereby increasing the risk for cervical ...
Callens, Steven   +4 more
core   +3 more sources

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

open access: yesAdvanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li   +17 more
wiley   +1 more source

Quantitative Screening of Cervical Cancers for Low-Resource Settings: Pilot Study of Smartphone-Based Endoscopic Visual Inspection After Acetic Acid Using Machine Learning Techniques [PDF]

open access: yes, 2020
Background: Approximately 90% of global cervical cancer (CC) is mostly found in low- and middle-income countries. In most cases, CC can be detected early through routine screening programs, including a cytology-based test.
Ahn, Yujin   +10 more
core   +1 more source

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li   +12 more
wiley   +1 more source

Larval therapy for leg ulcers (VenUS II) : randomised controlled trial [PDF]

open access: yes, 2009
Objective To compare the clinical effectiveness of larval therapy with a standard debridement technique (hydrogel) for sloughy or necrotic leg ulcers. Design Pragmatic, three armed randomised controlled trial.
Bland, J. Martin   +10 more
core   +3 more sources

Cervical intraepithelial neoplasia. [PDF]

open access: yesJournal of Clinical Pathology, 1982
The theoretical and practical reasons for replacing the terms "cervical dysplasia" and "cervical carcinoma in situ" by the single diagnostic entity of "cervical intraepithelial neoplasia" are reviewed and the advantages and drawbacks of this newer terminology discussed.
C H, Buckley, E B, Butler, H, Fox
openaire   +2 more sources

Functional Advantage of Central Pancreatectomy Over Distal Pancreatectomy for Benign or Low‐Grade Malignant Tumors: A Comparative Analysis Based on 75‐g Oral Glucose Tolerance Test

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Central pancreatectomy (CP) better preserves postoperative pancreatic endocrine function than distal pancreatectomy for benign or low‐grade malignant tumors. The 75‐g oral glucose tolerance test demonstrated that CP maintained insulin secretion and glucose tolerance, highlighting its clinical advantage as a function‐preserving procedure.
Dongha Lee   +9 more
wiley   +1 more source

Individual risk of cervical intraepithelial neoplasia progression in patients with chronic cervicitis

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2016
We proposed predictive method of cervical intraepithelial neoplasia progression in women with chronic cervicitis, it is favorable one in routine clinical practice.
O. M. Bokach, A. V. Tishkov
doaj   +1 more source

Contralateral prophylactic mastectomies. Correlations between primary tumor and histological findings of controlateral breast [PDF]

open access: yes, 2016
Backgound: In Italy in 2015 48,000 new cases of breast carcinomas were diagnosed. Women who are diagnosed with breast cancer have a significant risk of developing contralateral breast cancer during the rest of their lives and this risk is closely ...
Amanti, Claudio   +10 more
core   +1 more source

Edge Information‐Augmented Auxiliary Diagnosis Method for Cervical Cancer in Medical Decision‐Making Systems

open access: yesAdvanced Intelligent Systems, EarlyView.
To address the problems of insufficient utilization of multiscale features and inefficient feature sharing between tasks in the model, this study proposes an edge‐enhanced intelligent cervical cancer screening method that achieves feature reuse and improves efficiency by jointly optimizing nucleolus segmentation and lesion classification.
Li Wen   +4 more
wiley   +1 more source

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