Results 61 to 70 of about 30,616 (296)
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua+9 more
wiley +1 more source
Liver Transplantation for Alagille's Syndrome [PDF]
Twenty-three children with Alagille's syndrome and end-stage liver disease underwent liver transplantation with cyclosporine and low-dose steroid immunosuppression. Two to 9 years (mean, 4.4 years) after surgery, 13 (57%) of the children were still alive,
Reyes, J+5 more
core +1 more source
Intrahepatic microenvironment greatly impacts duration and degree of HSCs activation and development of liver fibrosis. By inhibiting TGFβ‐E2F1‐driven production of profibrogenic factors (CTGF and THBS1), hepatocyte ChREBPα monitors hepatic microenvironment and suppresses the overactivation of HSCs.
Jian Zhang+10 more
wiley +1 more source
Tunneling nanotubes facilitate the transfer of long‐chain fatty acids, primarily arachidonic acid, from tumor cells to macrophages, leading to lipid accumulation and activation of the PI3K‐Akt pathway. This drives a shift from the anti‐tumor CD5L⁺ phenotype to a pro‐tumor TREM2⁺ phenotype.
Meiru Chen+7 more
wiley +1 more source
Unclassified Diffuse Ductal Cholangiocarcinoma; Report of a Case
Cholangiocarcinoma (CCA) is the second most common malignant tumor of the liver. It is simply classified as intrahepatic and extrahepatic CCA (including perihilar and distal extra hepatic CCA) according to the anatomic localization.
Ünal Aydın+6 more
doaj +1 more source
A case of distal extrahepatic cholangiocarcinoma with two positive resection margins [PDF]
Cholangiocarcinoma is an uncommon primary malignancy of the biliary tract that is challenging to diagnose and treat effectively due to its relatively silent and late clinical presentation.
Andersen+42 more
core +2 more sources
CXCL6's function in cholangiocarcinoma is underexplored. Here it is discovered that CXCL6 is upregulated in cholangiocarcinoma tissues and promotes proliferation and metastasis of it. CXCL6 functions through the CXCR1/2‐JAK‐STAT/PI3K axis and reshaping tumor lipid metabolism.
Tian He+15 more
wiley +1 more source
Background An outbreak of cholangiocarcinoma in Japan has led to widespread concern among workers in printing plants. In March 2013, the Japanese Ministry of Health, Labour and Welfare, confirmed a causal relationship between cholangiocarcinoma and long ...
Daisuke Ogawa+9 more
doaj +1 more source
Liver fluke infections occur in people worldwide. In some low-income regions, a combination of ecological, agricultural, and culinary factors leads to a very high prevalence of infection but, in higher-income regions, infections are uncommon.
Harrington, David+2 more
core +1 more source
Our aim was to compare the outcomes of preoperative chemotherapy with postoperative chemotherapy in patients with resectable colorectal liver metastases treated with CAPOX‐Bev. We demonstrated that both preoperative and postoperative CAPOX‐Bev were safely administered, and preoperative chemotherapy showed a numerically higher treatment compliance rate ...
Yuji Takakura+15 more
wiley +1 more source