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Intrahepatic Cholangiocarcinoma [PDF]

Surgical Oncology Clinics of North America, 2014
Intrahepatic cholangiocarcinoma (ICC) is a rare tumor, with an increasing incidence worldwide and an overall poor prognosis. Symptoms are usually nonspecific, contributing to an advanced tumor stage at diagnosis. The staging system for ICC has recently been updated and is based on number of lesions, vascular invasion, and lymph node involvement ...
Kimberly M, Brown, Abhishek D, Parmar, David A, Geller   +2 more
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An extremely rare case of intrahepatic sarcomatoid cholangiocarcinoma

Radiology Case Reports, 2023
One uncommon histological subtype of intrahepatic cholangiocarcinoma is sarcomatoid intrahepatic cholangiocarcinoma. Histopathological and immunohistochemical tests are used to diagnose sarcomatoid intrahepatic cholangiocarcinoma, which frequently has a ...
Dau Quang Lieu, MD, Tran Ngoc Anh, MD, PhD, Tran-Thi Hoa, MD, Vu-Thi Phuong, MD, Nguyen Minh Duc, MD   +4 more
doaj   +1 more source

Sarcomatoid Intrahepatic Cholangiocarcinoma: A Case Report [PDF]

Advanced Ultrasound in Diagnosis and Therapy, 2023
Conventional two-dimensional ultrasonography revealed a hypoechoic mass in the liver of a middle-aged male patient. Enhanced ultrasound suggested intrahepatic cholangiocarcinoma. Enhanced MRI confirmed it as liver cancer.
Cuiwei Wang, MD, Xin-Hua Ye, MD
doaj   +1 more source

Successful Treatment of Advanced Intrahepatic Cholangiocarcinoma With a High Tumor Mutational Burden and PD-L1 Expression by PD-1 Blockade Combined With Tyrosine Kinase Inhibitors: A Case Report

Frontiers in Immunology, 2021
Advanced intrahepatic cholangiocarcinoma (iCCA) is not suitable for surgical treatment. Guided by the concept of precision medicine, preoperative systematic treatment may reshape the clinical outcomes of advanced intrahepatic cholangiocarcinoma patients.
Ze Zhang, Ze Zhang, Ze Zhang, Ze Zhang, Wenwen Zhang, Wenwen Zhang, Wenwen Zhang, Hongguang Wang, Bingyang Hu, Bingyang Hu, Bingyang Hu, Zhanbo Wang, Shichun Lu, Shichun Lu, Shichun Lu   +14 more
doaj   +1 more source

The VEGF expression associated with prognosis in patients with intrahepatic cholangiocarcinoma: a systematic review and meta-analysis

World Journal of Surgical Oncology, 2022
Objective To systematically evaluate the relationship between vascular endothelial growth factor (VEGF) and prognosis of intrahepatic cholangiocarcinoma by meta-analysis.
Chunping Cai, Xiaoji Wang, Qiurong Fu, Ai Chen   +3 more
doaj   +1 more source

Intrahepatic Cholangiocarcinoma

Seminars in Interventional Radiology, 2020
AbstractCholangiocarcinoma is the second most common primary malignancy of the liver. This review will focus on the mass-forming intrahepatic type of this disease and discuss the role of medical, surgical, and radiation oncology in managing this difficult disease.
Pouya, Entezari, Ahsun, Riaz
openaire   +4 more sources

Management of Intrahepatic Cholangiocarcinoma [PDF]

Journal of Clinical Medicine, 2021
Cholangiocarcinoma is a tumor that arises as a result of differentiation of the cholangiocytes and can develop from anywhere in the biliary tree. Subtypes of cholangiocarcinoma are differentiated based on their location in the biliary tree. If diagnosed early these can be resected, but most cases of intrahepatic cholangiocarcinoma present late in the ...
Sudha Kodali, Akshay Shetty, Soumya Shekhar, David W. Victor, Rafik M. Ghobrial   +4 more
openaire   +2 more sources

Immune cell atlas of cholangiocarcinomas reveals distinct tumor microenvironments and associated prognoses

Journal of Hematology & Oncology, 2022
Background Immunotherapy has demonstrated a limited clinical efficacy in approximately 5% of cholangiocarcinoma. The main challenges for an effective immunotherapy response in cholangiocarcinoma arise from the tumor microenvironment, which is poorly ...
Tao Xia, Keyu Li, Nan Niu, Yingkuan Shao, Ding Ding, Dwayne L. Thomas, Hao Jing, Kenji Fujiwara, Haijie Hu, Arsen Osipov, Chunhui Yuan, Christopher L. Wolfgang, Elizabeth D. Thompson, Robert A. Anders, Jin He, Yiping Mou, Adrian G. Murphy, Lei Zheng   +17 more
doaj   +1 more source

LncRNA MT1JP plays a protective role in intrahepatic cholangiocarcinoma by regulating miR-18a-5p/FBP1 axis

BMC Cancer, 2021
Background Cholangiocarcinoma is a common malignant tumor of digestive system. LncRNA metallothionein 1 J, pseudogene (MT1JP) has been reported to play tumor-suppressing roles in multiple cancers.
Wei Zhao, Jing Zhao, Xiao Guo, Yujie Feng, Bingyuan Zhang, Lantian Tian   +5 more
doaj   +1 more source

Novel Targeted Therapies for Advanced Cholangiocarcinoma

Medicina, 2021
Cholangiocarcinoma (CCA) includes a group of rare and aggressive hepatobiliary malignancies, including extrahepatic cholangiocarcinoma (eCCA) and intrahepatic cholangiocarcinoma (iCCA), with the former further subdivided into distal (dCCA) and perihilar ...
Alessandro Rizzo, Giovanni Brandi
doaj   +1 more source