Intrahepatic Cholangiocarcinoma
Techniques in Vascular and Interventional Radiology, 2015 Cholangiocarcinoma is a rare malignancy that arises from epithelial cells of the biliary system. Its desmoplastic histology and the heterogeneity of its presentation have contributed to its poor prognosis, with limited therapeutic options previously available.
A. B. Luk’yanchenko +5 more
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Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology [PDF]
, 2013 Cholangiocytes are epithelial cells lining the biliary epithelium. Cholangiocytes play several key roles in the modification of ductal bile and are also the target cells in chronic cholestatic liver diseases (i.e., cholangiopathies) such as PSC, PBC ...
Alvaro, Domenico +6 more
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Dual HER2 Blockade: An Emerging Option in Metastatic Biliary Tract Cancer?
Medicina, 2021 Biliary tract cancer (BTC) includes a heterogeneous group of aggressive and rare hepatobiliary malignancies, including gallbladder cancer, ampullary carcinomas, intrahepatic cholangiocarcinoma (iCCA), and extrahepatic cholangiocarcinoma, further ...
Angela Dalia Ricci, Alessandro Rizzo
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Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas [PDF]
, 2019 The bile duct system and pancreas show many similarities due to their anatomical proximity and common embryological origin. Consequently, preneoplastic and neoplastic lesions of the bile duct and pancreas share analogies in terms of molecular ...
Alvaro, D +10 more
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Journal of Pediatric Surgery Case Reports, 2020 A 13-year-old girl developed intrahepatic cholangiocarcinoma 7 years after laparoscopic extrahepatic bile duct resection and biliary reconstruction to treat Todani's type IV-A congenital biliary dilatation (CBD).
Kanako Omata +8 more
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A case of distal extrahepatic cholangiocarcinoma with two positive resection margins [PDF]
, 2016 Cholangiocarcinoma is an uncommon primary malignancy of the biliary tract that is challenging to diagnose and treat effectively due to its relatively silent and late clinical presentation.
Andersen +42 more
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Recurrent Intrahepatic Cholangiocarcinoma – Review [PDF]
Frontiers in Oncology, 2021 Intrahepatic cholangiocarcinoma (ICC) is the second-most common primary liver malignancy after hepatocellular carcinoma. While surgical resection with negative margin is the only curative treatment, ICC has very high rate of recurrence, up to 60-70% after curative resection.
Yuki Bekki +5 more
openaire +3 more sources
Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholagnitis [PDF]
, 2018 The non-invasive differentiation of malignant and benign biliary disease is a clinical challenge. Carbohydrate antigen 19-9 (CA19-9), leucine-rich α2-glycoprotein (LRG1), interleukin 6 (IL6), pyruvate kinase M2 (PKM2), cytokeratin 19 fragment (CYFRA21.1)
Blyuss, O +9 more
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Living Donor Liver Transplantation for Intrahepatic Cholangiocarcinoma
Current Oncology, 2022 Intrahepatic cholangiocarcinoma is in most transplant regions a contraindication for liver transplantation, even ruling out an active waiting list registration.
Falk Rauchfuß +5 more
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Treatment of hilar cholangiocarcinoma (Klatskin tumors) with hepatic resection or transplantation [PDF]
, 1998 Background: Because of the rarity of hilar cholangiocarcinoma, its prognostic risk factors have not been sufficiently analyzed. This retrospective study was undertaken to evaluate various pathologic risk factors which influenced survival after curative ...
Dvorchik, I +7 more
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