Recent Advances in Biocatalytic Promiscuity: Hydrolase-Catalyzed Reactions for Nonconventional Transformations [PDF]
, 2015 Financial support from the Spanish Ministerio de Economía y Competitividad (CTQ2013-44153-P) is grateful acknowledged. M.L.-I.
Gotor Fernández, Vicente +1 more
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Unprecedented Nitrite‐Dependent Aromatic Amination to Synthesize 2,4‐Diamino‐3‐Hydroxybenzoic Acid
ChemBioChem, Volume 27, Issue 2, January 2026.By comparing the biosynthetic gene clusters for natural products with 2,4‐diamino‐3‐hydroxybenzoic acid (2,4,3‐DAHBA) moiety and heterologous expression in Streptomyces albus, we identified nine genes required for the biosynthesis of 2,4,3‐DAHBA, including nitrite biosynthesis genes.
Ko Kuwabara +2 more
wiley +1 more source
Improvement of catalytic performance of lignin peroxidase for the enhanced degradation of lignocellulose biomass based on the imbedded electron-relay in long-range electron transfer route [PDF]
, 2016 Background: Although lignin peroxidase is claimed as a key enzyme in enzyme-catalyzed lignin degradation, in vitro enzymatic degradation of lignin was not easily observed in lab-scale experiments.
A Shah +25 more
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Food Science &Nutrition, Volume 14, Issue 1, January 2026.The Morchella mycelium polysaccharide (MP), a homogeneous α‐glucan (96.555% glucose, 5.7 kDa), protects against alcohol‐induced liver injury in mice. It reduces serum ALT/AST, improves lipid metabolism, and enhances antioxidants and inhibiting lipid peroxidation. Mechanistically, the MP suppresses Nlrp3 inflammasome‐mediated inflammation/pyroptosis and
Xinyu Hu +10 more
wiley +1 more source
Oxidative protein biogenesis and redox regulation in the mitochondrial intermembrane space [PDF]
, 2016 Mitochondria are organelles that play a central role in cellular metabolism, as they are responsible for processes such as iron/sulfur cluster biogenesis, respiration and apoptosis.
MacPherson, Lisa +2 more
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Structural and functional specialization of Bordetella pertussis DsbA for pertussis toxin folding
Protein Science, Volume 35, Issue 1, January 2026.Abstract Disulphide bonds (Dsbs) are essential for the folding, stability, and function of many secreted and membrane‐associated proteins in bacteria. In Gram‐negative species, these bonds are introduced by the Dsb enzyme family, with DsbA acting as the primary thiol oxidase.
Stephanie Penning +9 more
wiley +1 more source
Enzyme-catalyzed protein crosslinking [PDF]
, 2018 The process of protein crosslinking comprises the chemical, enzymatic, or chemoenzymatic formation of new covalent bonds between polypeptides. This allows (1) the site-directed coupling of proteins with distinct properties and (2) the de novo assembly of
Faccio, Greta +3 more
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Improving kinetic or thermodynamic stability of an azoreductase by directed evolution [PDF]
, 2014 Protein stability arises from a combination of factors which are often difficult to rationalise. Therefore its improvement is better addressed through directed evolution than by rational design approaches.
Campino, Lenea +5 more
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Surface Immobilized His-tagged Azurin as a Model Interface for the Investigation of Vectorial Electron Transfer in Biological Systems [PDF]
, 2015 A model system for the electrochemical investigation of vectorial electron transfer in biological systems was designed, assembled and characterized. Gold electrodes, functionalized with a -OCH3 terminated, aromatic self-assembled monolayer, were used as ...
Berto, Marcello +9 more
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Lipoproteins of Mycobacterium tuberculosis : an abundant and functionally diverse class of cell envelope components [PDF]
, 2004 Mycobacterium tuberculosis remains the predominant bacterial scourge of mankind. Understanding of its biology and pathogenicity has been greatly advanced by the determination of whole genome sequences for this organism.
Harrington, Dean, Sutcliffe, Iain
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