Results 71 to 80 of about 6,297 (161)

Why Leave a Job Half Done? Recent Progress in Enzymatic Deracemizations [PDF]

open access: yes, 2015
Financial support of this work by the Spanish MICINN (Projects CTQ2011-24237 and CTQ2013-44153) is gratefully ...
Díaz Rodríguez, Alba   +2 more
core   +2 more sources

Intramolecular fluorescence correlation spectroscopy in a feedback tracking microscope [PDF]

open access: yes, 2009
We derive the statistics of the signals generated by shape fluctuations of large molecules studied by feedback tracking microscopy. We account for the influence of intramolecular dynamics on the response of the tracking system, and derive a general expression for the fluorescence autocorrelation function that applies when those dynamics are linear.
arxiv   +1 more source

A Cofactor Regeneration System for 2‐Aminobutyric Acid Production Based on Combined Cross‐Linked Enzyme Aggregates: Utilizing His‐Tagged Enzymes With Low‐Concentration Calcium Ions as Precipitant

open access: yesEngineering in Life Sciences, Volume 25, Issue 3, March 2025.
ABSTRACT Combined cross‐linked enzyme aggregates (combi‐CLEAs) represent a promising carrier‐free immobilized enzyme technology. This study describes the preparation of combi‐CLEAs comprising leucine dehydrogenase (LeuDH) and formate dehydrogenase (FDH) for the regeneration of cofactor nicotinamide adenine dinucleotide necessary for 2‐aminobutyric acid
Jingran Liu   +8 more
wiley   +1 more source

Disulfides as redox switches : from molecular mechanisms to functional significance

open access: yes, 2010
The molecular mechanisms underlying thiol-based redox control are poorly defined. Disulfide bonds between Cys residues are commonly thought to confer extra rigidity and stability to their resident protein, forming a type of proteinaceous spot weld. Redox
Fan, Samuel W.   +2 more
core   +1 more source

Structure and Function of Bacillus subtilis YphP, a Prokaryotic Disulfide Isomerase with a CXC Catalytic Motif†,‡ [PDF]

open access: yes, 2009
: The DUF1094 family contains over 100 bacterial proteins, all containing a conserved CXCmotif, with unknown function. We solved the crystal structure of the Bacillus subtilis representative, the product of the yphP gene.
Andrzej Joachimiak   +9 more
core   +2 more sources

Banana skin: a novel material for a low-cost production of laccase [PDF]

open access: yesarXiv, 2008
Laccases (benzenodiol: oxygen oxidoreductases; EC 1.10.3.2) are multicopper oxidases of wide substrate specificity mainly found in white-rot fungi, which are the only microorganisms able to degrade the whole wood components, but they are also expressed in bacteria and higher plants. Laccases are used currently in biotechnological processes because this
arxiv  

Short to long-range charge-transfer excitations in the zincbacteriochlorin-bacteriochlorin complex: a Bethe-Salpeter study [PDF]

open access: yes, 2012
We study using the Bethe-Salpeter formalism the excitation energies of the zincbacteriochlorinbacteriochlorin dyad, a paradigmatic photosynthetic complex. In great contrast with standard timedependent density functional theory calculations with (semi)local kernels, charge transfer excitations are correctly located above the intramolecular Q-bands ...
arxiv   +1 more source

Folding of a single domain protein entering the endoplasmic reticulum precedes disulfide formation [PDF]

open access: yes, 2017
The relationship between protein synthesis, folding and disulfide formation within the endoplasmic reticulum (ER) is poorly understood. Previous studies have suggested pre-existing disulfide links are absolutely required to allow protein folding and ...
Bulleid, Neil J.   +3 more
core   +1 more source

Multi-scale Molecular Simulations on Respiratory Complex I [PDF]

open access: yesChemical Biology No. 5 (2018), 2019
Complex I (NADH:ubiquinone oxidoreductase) is a redox-driven proton pump that powers synthesis of adenosine triphosphate (ATP) and active transport in most organisms. This gigantic enzyme reduces quinone (Q) to quinol (QH2) in its hydrophilic domain, and transduces the released free energy into pumping of protons across its membrane domain, up to ca ...
arxiv  

Richard Nelson Perham. 27 April 1937—14 February 2015 [PDF]

open access: yes, 2018
Richard Nelson Perham, FRS, FMedSci, FRSA, was a British professor of structural biochemistry. He undertook his academic career at the University of Cambridge, holding positions as lecturer, reader, chair and head of the Department of Biochemistry, as ...
Charoy, François   +6 more
core   +2 more sources

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