Results 201 to 210 of about 376,249 (344)

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

Clinical Pharmacology &Therapeutics, EarlyView.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher, John Mann, Anik Chaturbedi, Shilpa Chakravartula, Hamed Meshkin, Affan Affan, Alexander Galluppi, Ji Young Kim, Nigar Karimli, Yue Han, Zachary Dezman, Jeffry Florian, Zhihua Li   +12 more
wiley   +1 more source

Intramuscular Transplantation Improves Engraftment Rates for Esophageal Patient-Derived Tumor Xenografts

, 2015
Matthew Read, David Liu, Cuong Duong, Carleen Cullinane, William K. Murray, Christina M. Fennell, Jake Shortt, David Westerman, Paul Burton, Nicholas J. Clemons, Wayne A. Phillips   +10 more
openalex   +2 more sources

Major Adverse Cardiac Events with Ondansetron: A Systematic Review

Clinical Pharmacology &Therapeutics, EarlyView.
Evidence base: 170 randomized trials, 23,421 adults, predominantly single‐dose IV ondansetron, mean follow‐up 20 days. Observed outcomes: Major adverse cardiac events were rare, no ventricular arrhythmias or torsades de pointes observed. Conclusion: Ondansetron was not associated with increased mortality or serious cardiac arrhythmias in adult ...
Michael Cristian Garcia, Bhavya Gandhi, Faisal Quadri, Mahnoor Shahab, Kassie Rong, Genevieve Ramnarine, Ishleen Sudan, Sophia Zhang, Michelle Yu, Sara Mojdehi, Lawrence Mbuagbaw, Anne M. Holbrook   +11 more
wiley   +1 more source

Intramuscular neural distribution of the soleus for botulinum neurotoxin injection: application to spasticity. [PDF]

Sci Rep
Yi KH, Hu H, Hwang SO, Lee JH, Lee HJ.
europepmc   +1 more source

Optimizing antenatal corticosteroid therapy for improving outcome of premature infants. [PDF]

, 2019
A Donaldson, Augusto F. Schmidt, CL Elliott, D Roberts, E Asztalos, EP Davis, F Althabe, F Waffarn, GC Liggins, GC Liggins, HG Liley, JP Vogel, Kristi L. Watterberg, M Della Torre, P Ballabh, Philip L. Ballard, PL Ballard, PL Ballard, RS Egerman, SE Tsuei   +19 more
core   +1 more source

Population Pharmacokinetics of Clesrovimab in Preterm and Full‐Term Infants

Clinical Pharmacology &Therapeutics, EarlyView.
Clesrovimab is a half‐life extended monoclonal antibody targeting the respiratory syncytial virus fusion protein. Three studies (phase Ib/IIa [MK‐1654‐002], phase IIb/III [CLEVER], and phase III [SMART]) were conducted to evaluate the efficacy, safety, and pharmacokinetics (PK) of clesrovimab in infants.
Ziheng Hu, Farina Hellmann, Xiaowei Zang, Nele Plock, Keyur Parmar, Radha A. Railkar, S. Y. Amy Cheung, Brian M. Maas, Ferdous Gheyas   +8 more
wiley   +1 more source

Diagnosis and Treatment Approach for Giant Muscle Hematoma of the Thigh Due to a Post-traumatic Arteriovenous Fistula: A Case Report. [PDF]

Cureus
Tanabu T, Ohshika S, Saruga T, Fujita Y, Kakehata S, Kakeda S, Ishibashi Y.   +6 more
europepmc   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Congenital Intramuscular Cavernous Hemangioma: A Rare and Underreported Entity. [PDF]

Cureus
Vignesh H, Kumar PG, Selvamuthukumaran S, B V S, K G M.   +4 more
europepmc   +1 more source

Effects of increased intramuscular temperature on characteristics of muscular fatigue in vivo

, 1977
Norman David Keane
openalex   +1 more source