Swiss Medical Weekly, 2017 BACKGROUND Vitamin B12 (VB12) deficiency can be treated with oral high-dose substitution or intramuscular (IM) injection of VB12. Whenever alternative routes of administration exist, patient preferences should be considered when choosing the ...
Corina Metaxas +5 more
doaj +1 more source
Factors influencing in vivo transduction by recombinant adeno-associated viral vectors expressing the human factor IX cDNA. [PDF]
, 2001 Long-term expression of coagulation factor IX (FIX) has been observed in murine and canine models following administration of recombinant adeno-associated viral (rAAV) vectors into either the portal vein or muscle. These studies were designed to evaluate
Davidoff, A +5 more
core +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source
Pharmacokinetics and Bioavailability of Doxycycline Following Parenteral Administration in Rabbits
Acta VeterinariaDoxycycline, a member of the tetracycline family, is widely used in various species to treat infections caused by bacteria susceptible to this antibiotic. However, data on the pharmacokinetics of this drug in rabbits are scarce. The aim of this study was
Martínez José +4 more
doaj +1 more source
Comparison of antibody titres between intradermal and intramuscular rabies vaccination using inactivated vaccine in cattle in Bhutan : a thesis presented in the partial fulfilment of the requirements for the degree of Master of Veterinary Science at Massey University, Palmerston North, New Zealand [PDF]
, 2018 In developing countries, the cost of vaccination limits the use of prophylactic rabies vaccination, especially in cattle. Intradermal vaccination delivers antigen directly to an area with higher number of antigen-presenting cells.
Wangmo, Karma
core
Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME
Advanced Functional Materials, EarlyView.A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li +10 more
wiley +1 more source
Pure Intramuscular Osteolipoma
Journal of Korean Neurosurgical Society, 2013 Ossified lipoma or osteolipoma are rarely reported. It is defined as a histologic variant of lipoma that has undergone osseous metaplasia. Osteolipoma presents with a dominant osseous component within a lipoma. We report a case of a histologically confirmed osteolipoma on the nuchal ligament independent of bone. The patient was a 51-year-old female who
Yang, Jin Seo +3 more
openaire +2 more sources
4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles
Advanced Functional Materials, EarlyView.Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner +12 more
wiley +1 more source
Slow responder against methotrexate 50 mg intramuscular in severe psoriatic patients: A case series
Dermatology Reports, 2019 Methotrexate is the drug of choice used on moderate to severe psoriasis. The limited availability of oral tablet methotrexate stimulates the initiation of the protocol therapy 50 mg intramuscular methotrexate weekly in six consecutive weeks for severe ...
Niken Kusumaningrum +4 more
doaj +1 more source
Vaccines, 2020 Leptospirosis vaccines with higher potency and reduced adverse effects are needed for human use. The carboxyl terminal domain of leptospiral immunoglobulin like protein A (LigAc) is currently the most promising candidate antigen for leptospirosis subunit
Teerasit Techawiwattanaboon +7 more
doaj +1 more source