Results 51 to 60 of about 376,249 (344)

A Single-Dose Intramuscular Nanoparticle Vaccine With or Without Prior Intrauterine Priming Triggers Specific Uterine and Colostral Mucosal Antibodies and Systemic Immunity in Gilts but Not Passive Protection for Suckling Piglets

Frontiers in Veterinary Science, 2022
An effective single-dose vaccine that protects the dam and her suckling offspring against infectious disease would be widely beneficial to livestock animals.
Pooja Choudhary, Amir Khajavinia, Ramin Mohammadi, Siew Hon Ng, Nathalie Bérubé, Damayanthi Yalamati, Azita Haddadi, Heather L. Wilson, Heather L. Wilson, Heather L. Wilson   +9 more
doaj   +1 more source

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source

Efeitos sedativos da associação de Cetamina e Midazolam administrados pela via intranasal ou intramuscular em papagaio (Amazona aestiva e Amazona vinacea)

Pesquisa Veterinária Brasileira, 2013
A falta de protocolos de sedação seguros para uso em papagaios na literatura demonstra a necessidade de conhecer os anestésicos que são eficazes nestes animais.
Eduarda H. Bitencourt, Vanessa S. Padilha, Marcos Paulo A. de Lima, Suzane L. Beier, Aury N. de Moraes, Nilson Oleskovicz   +5 more
doaj   +1 more source

Intramuscular and Intradermal Electroporation of HIV-1 PENNVAX-GP^® DNA Vaccine and IL-12 Is Safe, Tolerable, Acceptable in Healthy Adults

Vaccines, 2020
Background: Several techniques are under investigation to improve the immunogenicity of HIV-1 DNA vaccine candidates. DNA vaccines are advantageous due to their ease of design, expression of multiple antigens, and safety.
Srilatha Edupuganti, Stephen C. De Rosa, Marnie Elizaga, Yiwen Lu, Xue Han, Yunda Huang, Edith Swann, Laura Polakowski, Spyros A. Kalams, Michael Keefer, Janine Maenza, Megan C. Wise, Jian Yan, Matthew P. Morrow, Amir S. Khan, Jean D. Boyer, Laurent Humeau, Scott White, Niranjan Y. Sardesai, Mark L. Bagarazzi, Peter B. Gilbert, James G. Kublin, Lawrence Corey, David B. Weiner, on behalf of the HVTN 098 Study Team, the NIAID-Funded HIV Vaccine Trials Network   +25 more
doaj   +1 more source

Plasma‐Polymerized Nanoparticles Presenting Fibrillin‐1 Drive Rapid Re‐Endothelialization of Vascular Grafts

Advanced Healthcare Materials, EarlyView.
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee, Yuen Ting Lam, Alex H. P. Chan, Praveesuda L. Michael, Timothy C. Mitchell, Jui Chien Hung, Miguel Santos, Khoon S. Lim, Richard P. Tan, Steven G. Wise   +9 more
wiley   +1 more source

An Iranian man with increased thigh mass due to a hydatid cyst

GMS Hygiene and Infection Control, 2020
Background: Hydatid cyst is a zoonotic infection caused by . Primary single-intramuscular hydatid disease is rare, even in endemic regions of the world.
Samiee-Rad, Fatemeh, Emami, Ali
doaj   +1 more source

Measurement of Force and Intramuscular Pressure Changes Related to Thrust Spinal Manipulation in an In Vivo Animal Model

Biology, 2022
Current knowledge regarding biomechanical in vivo deep tissue measures related to spinal manipulation remain somewhat limited. More in vivo animal studies are needed to better understand the effects viscoelastic tissue properties (i.e., dampening) have ...
William R. Reed, Carla R. Lima, Michael A. K. Liebschner, Christopher P. Hurt, Peng Li, Maruti R. Gudavalli   +5 more
doaj   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Pharmacokinetic Pattern of Menbutone in Calves after Single Intravenous and Intramuscular Administration

Animals
Menbutone is a choleretic agent currently used in Europe to treat digestive disorders in livestock and dogs. Pharmacokinetic parameters were established in 4-month Holstein calves after intravenous (IV) and intramuscular (IM) administration. The drug was
Raquel Diez, Jose M. Rodriguez, Cristina Lopez, Raul de la Puente, Matilde Sierra, M. Jose Diez, Nelida Fernandez, Juan J. Garcia, Ana M. Sahagun   +8 more
doaj   +1 more source

Multistrain models predict sequential multidrug treatment strategies to result in less antimicrobial resistance than combination treatment [PDF]

, 2016
Background Combination treatment is increasingly used to fight infections caused by bacteria resistant to two or more antimicrobials. While multiple studies have evaluated treatment strategies to minimize the emergence of resistant strains for single ...
Ahmad, Amais, Christiansen, Lasse Engbo, Græsbøll, Kaare, Matthews, Louise, Nielsen, Søren Saxmose, Olsen, John Elmerdahl, Toft, Nils, Zachariasen, Camilla   +7 more
core   +4 more sources