Results 101 to 110 of about 107,310 (319)

Inadequate quality of administration of intranasal corticosteroid sprays

, 2019
Corine Rollema,1,2 Eric N van Roon,1,2 Tjalling W de Vries3 1Department of Clinical Pharmacy and Pharmacology, Medical Centre Leeuwarden, Leeuwarden, The Netherlands; 2Groningen Research Institute of Pharmacy, Department Pharmaco therapy, Epidemiology ...
Rollema C, van Roon EN, de Vries TW
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Risk of injury associated with the sedative potential of second‐generation antihistamines: A nationwide retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Individual second‐generation antihistamines may possess differential sedative potential due to the variability in central histamine receptor H1 occupancy. This study aimed to evaluate whether the sedative potential of second‐generation antihistamines is associated with the risk of injury during Japan's pollen season. Methods We conducted a
Jumpei Taniguchi, Shotaro Aso, So Sato, Hideo Yasunaga   +3 more
wiley   +1 more source

Intranasal Sendai Virus Vaccination of Seropositive Children 1 to 2 Years of Age in a Phase I Clinical Trial Boosts Immune Responses Toward Human Parainfluenza Virus Type 1

Vaccines
Background/Objectives: Human parainfluenza virus type 1 (hPIV-1) is a major cause of serious respiratory diseases in young children. Annually, hPIV-1 results in approximately 10,000 hospitalizations in the United States due to croup, bronchiolitis, and ...
Elisabeth Adderson, Kim J. Allison, Kristen Branum, Robert E. Sealy, Bart G. Jones, Sherri L. Surman, Rhiannon R. Penkert, Randall T. Hayden, Charles J. Russell, Allen Portner, Karen S. Slobod, Julia L. Hurwitz   +11 more
doaj   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

The effect of long-term use of intranasal steroids on intraocular pressure

, 2016
Ali Şimşek,1 Cem Bayraktar,2 Sedat Doğan,2 Mehmet Karataş,2 Yasin Sarıkaya2 1Department of Ophthalmology, 2Department of Otolaryngology Head and Neck Surgery, Adıyaman University Research and Education Hospital, Adıyaman, Turkey Abstract: Long-term use
Sarıkaya Y, Karataş M, Bayraktar C, Şimşek A, Doğan S   +4 more
core  

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

PERBANDINGAN EFEKTIFITAS PENGGUNAAN KETAMIN INTRANASAL DAN FENTANYL INTRANASAL SEBAGAI ANALGETIK POST OPERASI BESAR [PDF]

, 2017
Monika Rachmafuri, S9813080005. Perbandingan Efektivitas Penggunaan Ketamin Intranasal dan Fentanyl Intranasal Sebagai Analgetik Post Operasi Besar. Pembimbing I: Sugeng BS, dr, SpAn. KMN. Pembimbing II: Fitri H, dr, SpAn.
Rachmafuri, Monika
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Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Influenza (flu) vaccine (live, intranasal) : what you need to know [Spanish]

Influenza (flu) vaccine (live, intranasal) : what you need to know [Spanish]Influenza (live, intranasal) VIS \u2013 Spanish (8/6/21)spanish_flu_live ...

core  

Brain delivery of vasoactive intestinal peptide (VIP) following nasal administration to rats

, 2003
The aim of this work was to study in rats the nasal route for the brain delivery of the vasoactive intestinal peptide (VIP) neuropeptide. After evaluating VIP stability in solutions obtained from nasal washes, the effect of formulation parameters (pH 4-9,
Dufès, Christine, Couet, William, Olivier, Jean-Christophe, Gaillard, Frédéric, Gaillard, Afsaneh, Muller, Jean-Marc   +5 more
core   +1 more source