Results 61 to 70 of about 9,819 (144)

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Endophthalmitis due to an intra-ocular linear foreign body in a cat

Journal of Feline Medicine and Surgery Open Reports, 2015
Case summary An unusual case of an intraocular linear foreign body that migrated from the oral cavity, causing a severe endophthalmitis, in a cat is described. A 2-year-old female domestic shorthair cat presented with signs of infection from the left eye
Esmeralda Delgado
doaj   +1 more source

Long‐Term Hydrophilic, Anti‐Clotting, and Anti‐Fibrotic Dynamic Covalent Silicone‐Based Biomaterials

Advanced Healthcare Materials, Volume 15, Issue 24, 25 June 2026.
Dynamic covalent crosslinking of a Schiff‐base silicone elastomer with hydrazide‐functionalized polymers is demonstrated to improve the long‐term hydrophilicity as well as the anti‐fouling and anti‐clotting properties of PDMS implants. The hydrazone‐functionalized material prevents hydrophobic recovery, resists clotting, and significantly reduces ...
Norma A. Garza Flores, Eva Mueller, Robert Bui, James C. Fredenburgh, Ruiqi Yin, Rawaa Hussain, Rida A. Malik, Thomas Kalab, Dabeer Abdul‐Azeez, Fei Xu, Michael Brook, Jeffrey I. Weitz, Todd Hoare   +12 more
wiley   +1 more source

An unusual case of nine cilia embedded in the retina after a perforating ocular injury

American Journal of Ophthalmology Case Reports, 2020
Purpose: To report an extremely rare case involving a 41-year-old man with nine intraocular cilia embedded in the retina after a perforating ocular injury caused by a metal wire.
Gabriel Z. Ramos, Thiago B. Goncalves, Arnaldo F. Bordon   +2 more
doaj   +1 more source

Advancing Flexible Pressure Sensors for Next‐Generation Medical Monitoring

Advanced Sensor Research, Volume 5, Issue 6, June 2026.
This review highlights recent advances in flexible pressure sensors for next‐generation medical monitoring. The sensing mechanisms, material and structural optimization strategies, and intelligent algorithms are systematically summarized. Emerging applications in cardiovascular, respiratory, neurological, laryngeal, and ocular disease monitoring are ...
Chunjun Su, Xingfa Gao, Rixuan Wang, Shuhua Yang, Yinglun Sun   +4 more
wiley   +1 more source

Intraocular Foreign Body: Ultrasound and CT Findings

Journal of Education and Teaching in Emergency Medicine, 2017
History of present illness: A 36-year-old male with no past medical history presented to the emergency department with left eye pain. Earlier that day, the patient reported pounding a metal object with a metal hammer, when a piece flicked up and struck ...
Maja Feldman, Kristi Shigyo, Amy Kaji
doaj   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Nonclinical Considerations for Support of Pregnancy and Lactation in Clinical Trials

Birth Defects Research, Volume 118, Issue 6, June 2026.
ABSTRACT Background Pregnant and breastfeeding individuals remain underrepresented in clinical drug development, leaving health care providers and patients with limited data to inform treatment decisions. Current practice relies heavily on nonclinical developmental and reproductive toxicity (DART) studies in animals, while clinical trials typically ...
Dinesh Stanislaus, Christopher J. Bowman, Kimberly C. Brannen, Sarah N. Campion, Laura M. Carlson, Stephan Chalon, Anthony M. DeLise, Claudia Demarta‐Gatsi, Brian P. Enright, Wendy Halpern, Shermaine Mitchell‐Ryan, Vicki Sutherland, Karen Thacker, Kary Thompson, Belen Tornesi, Steven Van Cruchten, Ronald L. Wange, Tacey White, Connie L. Chen   +18 more
wiley   +1 more source

Unusual case of a graphite foreign body in the anterior chamber

Clinics and Practice, 2011
Retained intraocular graphite foreign bodies are uncommon. Although they are generally inert, they have been reported to cause severe inflammatory reaction and progressive damage to intraocular structures.
Anika Amritanand, Sheeja S. John, Swetha S. Philip, Deepa John, Sarada David   +4 more
doaj   +1 more source

Posterior segment intraocular foreign body with secondary retinal detachment in a phakic eye: a case report

, 2020
Intraocular foreign bodies (IOFBs) are an important cause of visual loss. The current case describes a case of retained intraocular foreign body with secondary retinal detachment in a phakic eye in a 38-year-old man.
Dr. Hardik Jain, Dr. Amit C Porwal, Dr. Pratik Mahajan   +2 more
core   +1 more source