Results 1 to 10 of about 1,361,126 (321)

Immunogenicity and Potential for Intraocular Inflammation of Intravitreal Anti-VEGF Drugs [PDF]

Current Therapeutic Research
Background: Concerns of intraocular inflammation associated with intravitreal administration of anti-VEGF drugs have been risen and the exact mechanism is not yet elucidated.
Hyeong Min Kim, MD, MSc, Se Joon Woo, MD, PhD   +1 more
doaj   +5 more sources

Ocular Microbiota and Intraocular Inflammation [PDF]

Frontiers in Immunology, 2020
The term ocular microbiota refers to all types of commensal and pathogenic microorganisms present on or in the eye. The ocular surface is continuously exposed to the environment and harbors various commensals. Commensal microbes have been demonstrated to
Jing Jing Li, Sanjun Yi, Lai Wei
doaj   +6 more sources

Sterile Intraocular Inflammation Associated With Faricimab

JAMA Ophthalmology
This case series study evaluates the characteristics and outcomes of sterile intraocular inflammation after injection of faricimab to treat neovascular age-related macular degeneration or diabetic macular edema.
Marianno Cozzi, Katrin Fasler, Daniel R Muth   +2 more
exaly   +6 more sources

Severe Intraocular Inflammation Following Intravitreal Faricimab

JAMA Ophthalmology
Importance Monitoring for and reporting potential cases of intraocular inflammation (IOI) in clinical practice despite limited occurrences in clinical trials, including experiences with relatively new intravitreal agents, such as brolucizumab ...
Loka Thangamathesvaran, J Fernando Arevalo   +1 more
exaly   +5 more sources

Visual Morbidity and Outcomes of Scleritis Associated with Intraocular Inflammation Compared to Isolated Scleritis. [PDF]

Ocul Immunol Inflamm, 2023
Purpose To compare visual outcomes, ocular complications and therapies for patients with scleritis-associated intraocular inflammation (SAI) and patients with isolated scleritis (IS).
Liao A, Fajoles-Vasseneix C, Rali A, Ward L, Fernandes A, Patel PS, O'Keefe G, Shantha JG, Yeh S.   +8 more
europepmc   +2 more sources

Bilateral Sterile Intraocular Inflammation Following Intravitreal Aflibercept 8 mg Injections: A Case Report [PDF]

Reports
Background and Clinical Significance: To report a case of bilateral sterile intraocular inflammation following intravitreal aflibercept 8 mg (Eylea HD) injections.
Ram Cohen, Tomer Kerman, Omer Trivizki
doaj   +2 more sources

Aflibercept high-dose (8mg) related intraocular inflammation (IOI) - a case series. [PDF]

BMC Ophthalmol
Monitoring for potential inflammatory events following intravitreal anti-vascular endothelial factor (VEGF) injection is crucial with the use of new agents such as aflibercept 8 mg.
Hoffmann L, Michels S, Eandi C, Karam MA, Figueiredo ECO, Hatz K.   +5 more
europepmc   +2 more sources

Manifestations of intraocular inflammation over time in patients on brolucizumab for neovascular AMD. [PDF]

Graefes Arch Clin Exp Ophthalmol, 2022
To describe the adverse events associated with brolucizumab, in particular the sequence of intraocular inflammation (IOI), retinal vasculitis (RV), and/or retinal vascular occlusion (RO).
Khoramnia R, Figueroa MS, Hattenbach LO, Pavesio CE, Anderesi M, Schmouder R, Chen Y, de Smet MD.   +7 more
europepmc   +2 more sources

Th17 Activation and Th17/Treg Imbalance in Prolonged Anterior Intraocular Inflammation after Ocular Alkali Burn. [PDF]

Int J Mol Sci, 2022
Ocular alkali burn (OAB) is a sight-threatening disease with refractory ocular inflammation causing various blinding complications. Th17 lymphocytes account for the pathogeneses of the autoimmune disease and chronic inflammation, but their role in ...
Yuan M, Qian X, Huang Y, Ma X, Duan F, Yang Y, Lou B, Lin X.   +7 more
europepmc   +2 more sources

Postprocedural Endophthalmitis or Postprocedural Intraocular Inflammation: A Diagnostic Conundrum [PDF]

Case Reports in Ophthalmology, 2021
We experienced an atypical endophthalmitis occurring post consecutively performed in-office procedures; an intravitreal injection (IVI) of ranibizumab followed by an anterior chamber (AC) paracentesis performed twice in an eye with neovascular glaucoma ...
Aisha Al Busaidi, Ahmed Al-Hinai
doaj   +2 more sources