Results 1 to 10 of about 11,617 (148)

Proteome Analysis of Aflibercept Intervention in Experimental Central Retinal Vein Occlusion

open access: yesMolecules, 2022
Aflibercept is a frequently used inhibitor of vascular endothelial growth factor (VEGF) in the treatment of macular edema following central retinal vein occlusion (CRVO).
Jakob Grauslund   +2 more
exaly   +3 more sources

Current role of aflibercept in retinopathy of prematurity – A review [PDF]

open access: yesIndian Journal of Ophthalmology
The introduction of intravitreal anti-vascular endothelial growth factor (VEGF) therapy has transformed the management of severe retinopathy of prematurity (ROP) in the zone I/zone II posterior region and aggressive ROP by enabling rapid disease ...
Devesh Kumawat   +2 more
doaj   +2 more sources

Aflibercept [PDF]

open access: yesClinical Cancer Research, 2013
Abstract Aflibercept, an intravenously administered anti-VEGF and antiplacental growth factor (PlGF) agent, has recently been approved by the U.S. Food and Drug Administration in combination with 5-fluorouracil, leucovorin, and irinotecan (FOLFIRI) for the treatment of patients with metastatic colorectal cancer who have previously ...
Kristen K, Ciombor   +2 more
  +6 more sources

Assessment of mouse VEGF neutralization by ranibizumab and aflibercept.

open access: yesPLoS ONE, 2022
PurposeTo assess the interaction between ranibizumab, aflibercept, and mouse vascular endothelial growth factor (VEGF), both in vivo and in vitro.MethodsIn vivo, the effect of intravitreal injection of ranibizumab and aflibercept on oxygen induced ...
Yusuke Ichiyama   +7 more
doaj   +1 more source

Ultrastructural features of epiretinal membranes after intravitreal injection of various doses of aflibercept in patients with proliferative diabetic retinopathy

open access: yesJournal of Ophthalmology, 2021
Background: Proliferative diabetic retinopathy (PDR) can cause a loss of vision due to complications like vitreous hemorrhage and tractional retinal detachment, which require vitrectomy.
Vira S. Ponomarchuk   +2 more
doaj   +1 more source

Transient Vision Loss Associated with Prefilled Aflibercept Syringes

open access: yesOphthalmology Science, 2022
Purpose: To describe cases of significant vision loss after intravitreal aflibercept administration using prefilled syringes (PFS) and to study the relationships among syringe design, injection speed, and injection force.
Daniel J. Lee, MD   +4 more
doaj   +1 more source

Features of aflibercept plus hyperbaric oxygen therapy for diabetic macular edema

open access: yesJournal of Ophthalmology, 2022
Background: Diabetes mellitus (DM) is a disease characterized by chronic hyperglycemia and a cascade of pathological vascular alterations leading to diabetic retinopathy (DR) and diabetic macular edema (DME).
V. O. Drozdov, V. M. Sakovych
doaj   +1 more source

Treatment Frequency and Dosing Interval of Ranibizumab and Aflibercept for Neovascular Age-Related Macular Degeneration in Routine Clinical Practice in the USA. [PDF]

open access: yesPLoS ONE, 2015
To compare treatment patterns of intravitreal ranibizumab and aflibercept for the management of neovascular age-related macular degeneration (nAMD) in a real-world setting over the first 12 months of treatment.A proprietary clinical database was used to ...
Alberto Ferreira   +5 more
doaj   +1 more source

Comparative study between the effect of intravitreal injection of Ranibizumab and Aflibercept on macular oedema secondary to branch retinal vein occlusion [PDF]

open access: yesAl-Azhar International Medical Journal, 2022
Background: Occlusion of retinal veins is a mutual disorder that affect the retina usually occurs when blood clot obstructs a retinal vein. Aim of the work: To compare the effects of Ranibizumab versus Aflibercept intravitreal injections on macular edema
Ahmed Tawfik   +2 more
doaj   +1 more source

Two-Week Aflibercept or Erlotinib Administration Does Not Induce Changes in Intestinal Morphology in Male Sprague–Dawley Rats But Aflibercept Affects Serum and Urine Metabolic Profiles

open access: yesTranslational Oncology, 2019
Gastrointestinal toxicity is a frequently observed adverse event during cancer treatment with traditional chemotherapeutics. Currently, traditional chemotherapeutics are often combined with targeted biologic agents.
Richard A. Forsgård   +8 more
doaj   +1 more source

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