Results 111 to 120 of about 154,174 (348)

Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis

open access: yesMed Research, EarlyView.
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang   +7 more
wiley   +1 more source

Low‐dose versus high‐dose methylprednisolone for children with severe Mycoplasma pneumoniae pneumonia (MCMP): A randomized controlled trial

open access: yesPediatric Investigation, EarlyView.
Although macrolides combined with glucocorticoids can prevent long‐term pulmonary lesions by severe Mycoplasma pneumoniae pneumonia (MPP), evidence regarding glucocorticoid dose is lacking. We found that high‐dose methylprednisolone compared to low‐dose did not reduce long‐term pulmonary lesions of severe MPP in Chinese children, but significantly ...
Baoping Xu   +29 more
wiley   +1 more source

Potential Therapeutic Actions of Flavonoids Present in Propolis That Modulate Vascular Endothelial Growth Factor Signaling to Regulate Angiogenesis

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Propolis is a plant‐derived substance collected by honeybees that has a range of potential therapeutic applications. Propolis consists of resins, waxes, and fatty acids, as well as essential oils and other organic compounds. The pharmacologically active components of propolis include phenols and flavonoids, among others.
Yipeng Lin   +7 more
wiley   +1 more source

Secretome Profiling in Axon Regeneration: Emerging Techniques and Therapeutic Translation

open access: yesSensory Neuroscience, EarlyView.
ABSTRACT The secretome refers to the in vivo ensemble of molecular entities that are found in interstitial spaces. It is then the mere secreted products of the cells, as all biomolecules in the interstitial cellular spaces also undergo modifications. The fractionated secretome may hold potential as a cell‐free therapy option due to its role in tissue ...
Maria D. Cabrera   +3 more
wiley   +1 more source

Intraocular pressure during haemodialysis

open access: yesIndian Journal of Ophthalmology, 1988
Intraocular pressure was measured before, at 2 hours & after haemodialysis in 75 uraemic patients of Indian origin, undergoing haemodialysis. There was no significant rise in intra-ocular pressure in these patients.
Sud R, Chhabra S, Sandhu J, Bansal P
doaj  

Effect of Carbon Dioxide on Intraocular Pressure in Anesthetized Man [PDF]

open access: bronze, 1964
Yong Hee Han   +2 more
openalex   +1 more source

The Challenges and Opportunities of Protein Coronas for Nanoscale Biomolecular Sensing

open access: yesSmall, EarlyView.
Nanoscale biomolecular sensors, or “nanobiosensors”, have enabled rapid detection of analytes with high sensitivity and specificity. In biological fluids, however, nanoscale objects are surrounded by biomolecules, that form an evolving encapsulating surface layer, commonly known as the protein corona.
Samuel Cheeseman   +6 more
wiley   +1 more source

Single-cell RNA sequencing analysis of the retina under acute high intraocular pressure

open access: yesNeural Regeneration Research
High intraocular pressure causes retinal ganglion cell injury in primary and secondary glaucoma diseases, yet the molecular landscape characteristics of retinal cells under high intraocular pressure remain unknown. Rat models of acute hypertension ocular
Shaojun Wang   +7 more
doaj   +1 more source

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