Results 21 to 30 of about 1,239,984 (109)

Patterns of BAP1 protein expression provide insights into prognostic significance and the biology of uveal melanoma

The Journal of Pathology: Clinical Research, Volume 4, Issue 1, Page 26-38, January 2018., 2018
Abstract Uveal melanoma (UM) is a rare aggressive intraocular tumour with a propensity for liver metastases, occurring in ∼50% of patients. The tumour suppressor BAP1 is considered to be key in UM progression. Herein, we present the largest study to date investigating cellular expression patterns of BAP1 protein in 165 UMs, correlating these patterns ...
Neil Farquhar, Sophie Thornton, Sarah E Coupland, Judy M Coulson, Joseph J Sacco, Yamini Krishna, Heinrich Heimann, Azzam Taktak, Colleen M Cebulla, Mohamed H Abdel‐Rahman, Helen Kalirai   +10 more
wiley   +1 more source

Brachytherapy and endoresection in the treatment of choroidal melanoma a review of patients treated in South Africa [PDF]

, 2012
Includes bibliographical references.This study is a retrospective cohort analysis of patients undergoing two different treatment modalities (brachytherapy and endoresection) for medium sized choroidal melanoma.
Rice, James C
core   +1 more source

Ultradeep sequencing detects GNAQ and GNA11 mutations in cell‐free DNA from plasma of patients with uveal melanoma

Cancer Medicine, Volume 2, Issue 2, Page 208-215, April 2013., 2013
Uveal melanoma is a frequently metastasizing intraocular tumour. We detected GNAQ or GNA11 Q209 mutations in the plasma of 9 out of 22 metastasized patients using ultradeep sequencing (2–38% mutant reads). The results show that ultradeep amplicon sequencing can be used to detect tumour DNA in plasma of metastasized uveal melanoma patients.
Claudia H. D. Metz, Max Scheulen, Norbert Bornfeld, Dietmar Lohmann, Michael Zeschnigk   +4 more
wiley   +1 more source

Proton beam radiotherapy in the management of uveal melanoma: clinical experience in Scotland [PDF]

, 2008
<p>Aim: To evaluate proton-beam radiotherapy (PBRT) in the management of uveal melanoma in Scotland.</p> <p>Methods: A retrospective review was undertaken on all patients receiving PBRT for uveal melanoma (1994–2005).
McConnachie, A., Alex Taylor, Alex Kacperek, Aziz, S., Samir Aziz, Kemp, E., Andrzej McConnachie, Ewan Kemp, Kacperek, A., Taylor, A.   +9 more
core   +1 more source

The effectiveness of early lens extraction with intraocular lens implantation for the treatment of primary angle-closure glaucoma (EAGLE): study protocol for a randomized controlled trial [PDF]

, 2011
Glaucoma is the leading cause of irreversible blindness. Although primary open-angle glaucoma is more common, primary angle-closure glaucoma (PACG) is more likely to result in irreversible blindness.
Burr, JM, Vale L., Azuara-Blanco, Augusto; id_orcid, Gla, EIA-C, Friedman, D, Jimmy Lai, Cochran C., Ramsay C., Nolan, W, Cochran, C, Ramsay, C, Quayyum Zahidul, Azuara-Blanco A., Aung T., McDonald, A, Cochran, Claire, AzuaraBlanco, A, Zahidul Quayyum, McPherson, Gladys, Ramsay, Craig, Foster P., Friedman David, Lai Jimmy, Norrie, John David Taylor, Cochran Claire, McPherson Gladys, McDonald, Alison, Vale, L, Ramsay Craig, Winnie Nolan, Alison McDonald, Burr J.M., Burr, Jennifer M., Aung Tin, Paul Chew, null null, Azuara-Blanco, A, Quayyum, Z, McPherson, G, Azuara-Blanco, Augusto, Burr, Jennifer M, Quayyum, Zahidul, Effectiveness in Angle-closure Glaucoma of Lens Extraction (EAGL, Lai, Jimmy, Augusto Azuara-Blanco, Tin Aung, Foster, P, Norrie, John, Chew Paul, Burr Jennifer M, Foster, Paul, Effectiveness in Angle-closure Glaucoma of Lens Extraction (EAGLE) Study Group, Claire Cochran, David Friedman, Chew, Paul, Nolan, Winnie, Vale, Luke, Friedman D., Lai, J, Friedman, David, Chew P., McPherson G., Foster Paul, Norrie John, Norrie J., John Norrie, Lai J., Aung, T, Aung, Tin, Vale Luke, Craig Ramsay, Gladys McPherson, Paul Foster, McDonald A., McDonald Alison, Jennifer M Burr, Norrie, J, Chew, P, Nolan Winnie, Luke Vale, Quayyum Z., Nolan W., Azuara-Blanco Augusto   +82 more
core   +2 more sources

Tumor Environment of Retinoblastoma, Intraocular Cancer

, 2020
Retinoblastoma, an intraocular cancer primarily affecting children, interacts with surrounding intraocular and extraocular structures in the development and progression.
Jin Hyoung Kim, Kim, Jeong Hun, Kim, Jin Hyoung, Jo, Dong Hyun, Dong Hyun Jo, Jeong Hun Kim   +5 more
core   +1 more source

Postoperative IOP prophylaxis practice following uncomplicated cataract surgery: a UK-wide consultant survey [PDF]

, 2005
Background In order to minimise postoperative intraocular pressure (IOP) rise, after routine uncomplicated cataract surgery, prophylaxis may be adopted.
Dhillon, Baljean, Zamvar, Usha, Dhillon Baljean, Zamvar Usha   +3 more
core   +1 more source

Intraocular light scatter as modeled through a stratified medium [PDF]

, 2001
Intraocular light scatter is modeled through a stratified medium. It is shown that the eye lens possesses properties of an interference filter. In conditions that may mimic opacification, as found with cataract formation, such a filter may have stop ...
Pierscionek, Barbara, Dolgobrodov, Sergey G., Green, Roger   +2 more
core   +1 more source

A National Consensus Survey for Current Practice in Brain Tumor Management I: Antiepileptic Drug and Steroid Usage [PDF]

, 2020
Background: The Guideline Working Group of the Korean Society for Neuro-Oncology (KSNO) conducted a nationwide questionnaire survey for diverse queries faced in the treatment of brain tumors. As part I of the survey, the aim of this study is to evaluate
김세훈, 윤홍인, 장종희
core   +1 more source

Recurrence and massive extraocular extension of choroidal malignant melanoma after vitrectomy and endoresection

, 2014
Vitrectomy and endoresection is an alternative to enucleation for the treatment of large malignant choroidal melanoma. We report a rare case of extensive recurrence of choroidal malignant melanoma with extraocular extension 11 years after surgical ...
Khalil Ghasemi Falavarjani, Mehdi Modarres, Asgari Rezanejad   +2 more
core   +1 more source