Results 51 to 60 of about 97,305 (299)

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

open access: yesAdvanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández   +14 more
wiley   +1 more source

Intraoperative Cochlear Nerve Monitoring in Cochlear Implantation after Vestibular Schwannoma Resection

open access: yesAudiology Research, 2023
Background: The use of a cochlear implant (CI) for hearing rehabilitation after vestibular schwannoma (VS) resection is widely spreading. The procedure is usually performed simultaneously to tumor resection with a translabyrinthine approach.
Valerio Maria Di Pasquale Fiasca   +1 more
doaj   +1 more source

Real‐Time Holographic Feedback via Mixed Reality Sensorized Laryngoscope Training System Enhances Pediatric Intubation Training

open access: yesAdvanced Robotics Research, EarlyView.
We proposed a Mixed Reality Sensorized Laryngoscope Training System to provide real‐time holographic torque feedback during pediatric endotracheal intubation simulation. Visualization formats are evaluated to reduce tracking error and visual demand.
Jiaqi Li   +5 more
wiley   +1 more source

Comparative Efficacy of Intraoperative Patient State Index vs. Bi-Spectral Index in Patients Undergoing Elective Spine Surgery with Neuromonitoring Under General Anaesthesia: A Randomized Controlled Trial

open access: yesTurkish Journal of Anaesthesiology and Reanimation
Objective: Various electroencephalogram-based monitors have been introduced to objectively quantify anaesthesia depth. However, limited data are available on their comparative clinical efficacy in various surgical procedures.
Deepak Singla   +4 more
doaj   +1 more source

Intraoperative rectal ampullar manometry in spinal cord conus lipoma surgery in children

open access: yesХирургия позвоночника, 2019
Objective. To assess a potential of using intraoperative rectal ampullar manometry to prevent bladder dysfunction in surgical treatment of the spinal cord conus lipoma. Material and Methods.
Kirill V. Sysoev   +2 more
doaj   +1 more source

Schnider and Eleveld Models for Propofol Target-Controlled Infusion Anesthesia: A Clinical Comparison

open access: yesLife, 2023
Background: Various pharmacokinetic/pharmacodynamic (PK/PD) models have been developed to accurately dose propofol administration during total intravenous anesthesia with target-controlled infusion (TIVA-TCI). We aim to clinically compare the performance
Federico Linassi   +5 more
doaj   +1 more source

Brain tumors in eloquent areas: A European multicenter survey of intraoperative mapping techniques, intraoperative seizures occurrence, and antiepileptic drug prophylaxis. [PDF]

open access: yes, 2017
Intraoperative mapping and monitoring techniques for eloquent area tumors are routinely used world wide. Very few data are available regarding mapping and monitoring methods and preferences, intraoperative seizures occurrence and perioperative ...
Wager, Michel   +24 more
core   +1 more source

A Low‐Cost, Handheld Optical Stiffness Sensor for Minimally Invasive Surgery

open access: yesAdvanced Robotics Research, EarlyView.
A novel handheld stiffness sensor is presented for real‐time tissue stiffness characterization. By simultaneously sensing contact force and tissue deformation, the device enables accurate stiffness quantification without requiring precise manual control. This approach offers a promising solution for intraoperative tumor detection and minimally invasive
Qianyu Ma   +4 more
wiley   +1 more source

Intraoperative monitoring of the facial nerve [PDF]

open access: yesThe Laryngoscope, 1988
AbstractAnatomic preservation of the facial nerve, with maximal facial function, is one of the goals of acoustic neuroma surgery. Application of electrophysiologic monitoring techniques is useful in achieving this goal. Preoperative electromyography and nerve conduction studies provide important prognostic information for preservation of the nerve and ...
S G, Harner   +3 more
openaire   +2 more sources

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

open access: yesAdvanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng   +15 more
wiley   +1 more source

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