Results 61 to 70 of about 97,305 (299)

Should we use early less invasive hemodynamic monitoring in unstable ICU patients? [PDF]

, 2011
In the previous issue of Critical Care, Takala and colleagues presented the results of a multicenter study to investigate whether the early presence of less invasive hemodynamic monitoring improves outcome in patients admitted with hemodynamic ...
Maurizio Cecconi, Bennett, D, David Bennett, Cecconi, M   +3 more
core   +1 more source

Epigenetic Silencing of RFX7 Defines a Transcriptional Axis Linking Lactate Metabolism to Immune Checkpoint Therapy in Glioblastoma

Advanced Science, EarlyView.
Glioblastoma (GBM) exhibits RFX7 silencing via promoter hypermethylation, which downregulates PIK3IP1 to activate PI3K/AKT signaling, increase lactate accumulation, and enhance histone H4K12 lactylation. This lactylation upregulates PD‐L1/CSF1 expression and drives the immunosuppressive microenvironment formation.
Liying Han, Jinpeng Zhou, Gang Zhu, Fan Chen, Leiyang Li, Wenxing Cui, Fang Sun, Tian Feng, Yue Zhang, Qiang Wang, Shuoyao Ma, Chengxuan Guo, Ziwen Zhang, Kai Wang, Jiahui Wang, Liangbo Wang, Wencong Li, Chenyi Yuan, Haixiao Liu, Liang Wang, Yan Qu   +20 more
wiley   +1 more source

Intraoperative tourniquet-induced hyperthermia in a pediatric patient: a forgotten association -a case report- [PDF]

Korean Journal of Anesthesiology
Background The intraoperative use of tourniquets is associated with several complications, including hyperthermia. We present the first documented case of tourniquet-induced hyperthermia in a pediatric patient at our institution. Case A 5-year-old female
Tarek Tageldin, Muhammad Jaffar Khan, Temur Baykuziyev, Haitham Ahmed   +3 more
doaj   +1 more source

Manajemen Neuroanestesi pada Operasi Carotid Endarterectomy: Pasien dengan Riwayat Stroke Berulang

Jurnal Neuroanestesi Indonesia, 2021
Carotid endarterectomy (CEA) adalah prosedur bedah yang dilakukan untuk memulihkan aliran darah karotis dan mengurangi kejadian stroke embolik dan trombotik.
Chrismas Gideon Bangun, RR. Sinta Irina, Dewi Yulianti Bisri, Eri Surahman   +3 more
doaj   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Intraoperative monitoring during carotid endarterectomy : SEP versus EEG monitoring

, 1998
Carotid endarterectomy is a controversial surgery from several points of view, and the possibility of intraoperative stroke due to temporary carotid occlusion still raises great concern.
M. Schieppati, P. L. Vandone, E. Fava, F. Lang, E. Bortolani   +4 more
core   +1 more source

Transferable Deep Reinforcement Learning With Edge‐Contour‐Depth Fusion for Autonomous Wireless Capsule Endoscopy Navigation

Advanced Science, EarlyView.
This study presents an anatomical landmark‐guided DRL framework for autonomous wireless capsule endoscopy navigation. Using a lightweight edge‐contour‐depth fusion module, it achieves over 97% coverage across diverse gastric anatomies. To ensure reliability, a two‐stage sim‐to‐real pipeline with an adaptive dynamic programming controller mitigates ...
Haoxuan Wu, Haitao Gao, Qingyang Liu, Sishen Yuan, Haiyang Fang, Mingwu Su, Baijia Liang, Yongzun Yang, Long Bai, Wenzhen Dong, Dihong Xie, Shijian Su, Jiewen Lai, Shing Shin Cheng, Zhen Li, Xiuli Zuo, Hongliang Ren   +16 more
wiley   +1 more source

SDS‐CRISPR for Single‐Nucleotide Variant Detection

Advanced Science, EarlyView.
Structure‐disruption‐sensitive CRISPR (SDS‐CRISPR) converts structural instability into single‐nucleotide precision, thereby overcoming mismatch tolerance in canonical Cas12a and enabling versatile diagnostics across DNA, RNA, and microRNA targets. When applied to rapid IDH1 mutation detection for glioma genotyping and integrated with lateral‐flow ...
Xin Guan, Chong Guo, Jiongyu Zhang, Rui Yang, Yerramsetti Ramachandra, Chengyu Hou, Minjie Pei, Shuo Zhang, Kurt T. Schalper, Xingye Liu, Qian Wu, Ketan R. Bulsara, Changchun Liu   +12 more
wiley   +1 more source

Transesophageal echocardiography in the imaging of spinal cord structures – a systematic review of the literature

Journal of Ultrasonography
Transesophageal echocardiography enables visualization of structures within the spinal canal, particularly in the upper thoracic and lower cervical regions, but its diagnostic performance and clinical roles remain unclear.
Mendrala Martyna, Kosiński Sylweriusz, Darocha Tomasz, Podsiadło Paweł, Czober Tomasz, Mendrala Konrad   +5 more
doaj   +1 more source

Advancing Intraoperative Neurophysiological Monitoring With Human Reflexes [PDF]

Brainstem reflexes; Intraoperative neurophysiological monitoring; Spinal reflexesReflexos del tronc cerebral; Monitorització neurofisiològica intraoperatòria; Reflexos espinalsReflejos del tronco cerebral; Monitorización neurofisiológica intraoperatoria;
Diaz Baamonde, Alba, Choi, Jongsuk, Téllez, Maria J, Kim, Jun-Soon, Mirallave, ANa, Sanchez Roldan, Maria de los Angeles   +5 more
core   +1 more source