Results 121 to 130 of about 39,968 (294)

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

International Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer, Morghan C. Lucas, Vitus Prokosch, Thomas Keßler, Thomas Risch, Andreas Laner, Jan Henkel, Anna Benet‐Pagès, Ariane Hallermayr, Verena Steinke‐Lange, Elke Holinski‐Feder, Barbara Klink   +11 more
wiley   +1 more source

Neoadjuvant Atezolizumab and Chemotherapy for Non‐Squamous Non‐Small Cell Lung Cancer: Efficacy and Safety Results of an Open‐Label, Single‐Arm, Phase II Trial

International Journal of Cancer, EarlyView.
Surgery plus chemotherapy is a well‐established treatment protocol for resectable, locally advanced non‐small cell lung cancer (NSCLC). Nonetheless, survival gains remain limited, emphasizing the need for more effective treatments. Here, the authors evaluated a novel approach using a neoadjuvant immunotherapy‐chemotherapy regimen consisting of ...
Benedikt Niedermaier, Tilmann Bochtler, Florian Eichhorn, Raffaella Griffo, Laura V. Klotz, Michael Allgäuer, Albrecht Stenzinger, Helge Bischoff, Marc A. Schneider, Petros Christopoulos, Uwe Haberkorn, Claus Peter Heussel, Inka Zoernig, Felix J. F. Herth, Michael Thomas, Alexander Rölle, Hauke Winter, Axel Benner, Dirk Jaeger, Martin E. Eichhorn   +19 more
wiley   +1 more source

Prognostic Value of Perioperative Anemia in Neurosurgical‐Oncological Treatment of Spinal Metastases

International Journal of Cancer, EarlyView.
High perioperative morbidity in patients undergoing surgery for spinal metastases highlights the need to identify modifiable risk factors, particularly the underexplored role of anemia. This study assessed associations between perioperative hemoglobin levels and complications, recurrence, and mortality in patients treated surgically for spinal ...
Marija Janjic, Logman Khalafov, Juliane Dittmer, Saif‐Eldin Abedellatif, Tim Lampmann, Harun Asoglu, Mohammed Jaber, Haitham Alenezi, Muriel Heimann, Matthias Schneider, Motaz Hamed, Marcus Thudium, Hartmut Vatter, Mohammed Banat   +13 more
wiley   +1 more source

Intraoperative Radiotherapy

The Medical Journal of Okmeydani Training and Research Hospital, 2014
Matteo Ghilli, Manuela Roncella
openaire   +2 more sources

Electronic Brachytherapy: A Calibration Protocol in Terms of Absorbed Dose to Water"

Brazilian Journal of Radiation Sciences
New radiotherapy techniques have been innovative in recent decades with the aim of maximizing the dose to tumor tissue and reducing the dose to healthy tissue.
Fábio Sabará Dias, Orlando Rodrigues Jr, Maria da Penha Albuquerque Potiens   +2 more
doaj   +1 more source

The Pathophysiological effects of adjuvant preoperative chemotherapy and/or radiotherapy on patients with advanced rectal cancer [PDF]

, 2013
Introduction The modern treatment of colorectal cancer consists of surgery, with or without adjuvant pre-operative radiotherapy, chemotherapy or chemoradiotherapy (APT) for selected cases. In the United Kingdom, therapy may be given prior to surgery in
Rahmani, Samir
core  

Update on intraoperative radiotherapy: new challenges and issues

, 2018
Intraoperative radiotherapy (IORT) for breast cancer has challenged the standard external beam radiotherapy (EBRT) and has been shown to be non-inferior for treating early breast cancer in the past decade.
Esposito, Emanuela, Michael Douek, Emanuela Esposito, Douek, Michael   +3 more
core   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

The Effect of Intraoperative Boost Dose Radiotherapy on Wound Complications in Breast Cancer Patients Operated with Upper Outer Quadrantectomy by Using Intraglandular Flap Mobilization Technique

Acta Haematologica Oncologica Turcica
Aim: In this study, the technical aspects of intraoperative radiotherapy (IORT) application and its effect on early wound complications were evaluated. Methods: Fifty consecutive patients operated with upper outer quadrantectomy and intraglandular flap ...
Mujdat Turan, Niyazi Karaman, Lutfi Dogan, Mehmet Ali Gulcelik   +3 more
doaj   +1 more source

Mammography findings following electron intraoperative radiotherapy or external radiotherapy for breast cancer treatment

, 2011
Radiotherapy following breast cancer conserving surgery decreases the risks of local recurrence. Because 85% of breast cancers relapse in or around the surgical bed there has been some debate on the need for irradiating the whole breast.
FRASSON, A. L., CARVALHO, B. P. S. A., B.P.S.A. Carvalho, A.L. Frasson, SANTOS, M. M., BARROS, N. de, M.M. Santos, N. de Barros   +7 more
core   +1 more source