Results 141 to 150 of about 382,196 (290)

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

International Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer, Morghan C. Lucas, Vitus Prokosch, Thomas Keßler, Thomas Risch, Andreas Laner, Jan Henkel, Anna Benet‐Pagès, Ariane Hallermayr, Verena Steinke‐Lange, Elke Holinski‐Feder, Barbara Klink   +11 more
wiley   +1 more source

Development and challenges in performing intraoperative radiotherapy

Uvod: Radioterapija je poleg kirurgije in kemoterapije ena od treh glavnih načinov zdravljenja raka. Intraoperativna radioterapija je posebna obsevalna tehnika, ki se izvaja med operacijo. Omogoča nam natančno lokalizacijo ležišča tumorja, ki se obseva z
Volk, Nika, Zupan, Iza
core  

Second Breast‐Conserving Treatment for Ipsilateral Breast Tumor Recurrence: A Review of Patient Selection, Reirradiation Techniques, and Clinical Outcomes

International Journal of Cancer, EarlyView.
ABSTRACT Local recurrence after primary breast cancer treatment remains a complex clinical scenario in patients previously treated with breast‐conserving therapy and radiotherapy. For decades, salvage mastectomy was considered the standard treatment for ipsilateral breast tumor recurrence, largely because of concerns about local control after repeat ...
Cezara Cheptea, Youlia Kirova, Radu Iulian Mitrica, Mihaela Badea, Pierre Loap   +4 more
wiley   +1 more source

Safety of Pre-Operative Radiotherapy Combined With Intraoperative Radiotherapy for Retroperitoneal Sarcoma. [PDF]

J Surg Oncol
MacDonald M, Dougherty K, Pham V, Yanagihara TK, Kim HJ, Spanheimer PM.   +5 more
europepmc   +1 more source

Real‐World Experience With Multimodal Treatment of Resectable Stage II–III Non‐Small Cell Lung Cancer: A Single Institutional Analysis

International Journal of Cancer, EarlyView.
ABSTRACT Neoadjuvant therapy has recently become an integral component of multimodal treatment for resectable lung cancer. However, real‐world data on perioperative morbidity and treatment adherence remain limited. This study aimed to assess the feasibility and safety of different neoadjuvant treatment approaches applied within daily clinical routine ...
Raffaella Griffo, Benedikt Niedermaier, Laura V. Klotz, Marc Schneider, Michael Allgäuer, Marc Kriegsmann, Romina M. Roesch, Lena Brendel, Henrike Deissner, Farastuk Bozorgmehr, Petros Christopoulos, Michael Thomas, Hauke Winter, Martin E. Eichhorn, Florian Eichhorn   +14 more
wiley   +1 more source

Local recurrence in nipple-sparing mastectomy without intraoperative radiotherapy (IORT) in breast cancer. [PDF]

Gland Surg
Chirappapha P, Watanakun W, Lapkittichot S, Lertsithichai P, Suvikapakornkul R, Sukarayothin T, Leesombatpaiboon M, Wasuthit Y, Prasitmonthol R, Adireklarpwong L.   +9 more
europepmc   +1 more source

Outcomes Following Pancreatoduodenectomy With Arterial Resection: A NSQIP Analysis Comparing Trends in Patient Selection and Outcomes to Venous or no Vascular Resection Over 5 Years

International Journal of Cancer, EarlyView.
ABSTRACT Evaluation of arterial resection (AR) during pancreatoduodenectomy (PD) remains limited. This study compares PD with AR to PD with venous resection (VR) and no vascular resection (NVR). Patient demographics, outcomes, and changes over 5 years are evaluated.
Kevin Verhoeff, Alynne Kris Ribano, Daniel Kilburn, Carol‐Anne Moulton, Chaya Shwaartz, Trevor Reichman, Ian McGlivray, Sean Cleary   +7 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Metabolomic properties of the fluid from the surgical ligation after breast-conserving therapy and intraoperative radiotherapy. [PDF]

Sci Rep
Gdowicz-Kłosok A, Boguszewicz Ł, Skorupa A, Ciszek M, Amico MT, Krześniak M, Łasut-Szyszka B, Sokól M, Wydmański J.   +8 more
europepmc   +1 more source

Retrohepatic Vena Cava Encirclement, as Surrogate of Extensive Liver Manipulation During Caval Sparing Hepatectomy, Is a Risk Factor for Tumor Recurrence After Liver Transplantation for Hepatocellular Carcinoma

Journal of Surgical Oncology, EarlyView.
ABSTRACT Introduction In liver transplantation (LT) with a caval sparing (CS) approach, the presence of complete encirclement of inferior vena cava (IVC‐E) by hypertrophic segment 1 increases the technical complexity of hepatectomy. Thus, in LT for hepatocellular carcinoma (HCC), It may be suspected that the resulting greater liver manipulation and ...
Riccardo Pravisani, Claudio Bosio, Grazia Conte, Alex Borin, Amedeo Carraro, Federico Mocchegiani, Maria De Martino, Marco Vivarelli, Dario Lorenzin, Umberto Baccarani   +9 more
wiley   +1 more source