Background Pancreatic cancer is one of the most common fatal malignancies and has a poor prognosis. Surgical treatment is the most important treatment method, but there is a low rate of radical excision; moreover, the postoperative recurrence rate is ...
Xiaodong Song, Zili Shao, Huihong Liang
doaj +2 more sources
Intraoperative Radiotherapy in the Treatment of Breast Cancer: A Review of the Evidence [PDF]
The surgical treatment of early breast cancer has evolved from the removal of the entire breast and surrounding tissues (mastectomy) to the removal of the tumour together with a margin of healthy tissue (lumpectomy).
Norman R. Williams +2 more
doaj +4 more sources
High-dose Irradiation Stimulated Breast Tumor Microenvironment to Enhance Tumor Cell Growth and Decrease Tumor Cell Motility [PDF]
Background: Surgery and radiotherapy are two main modalities of breast cancer treatment. However, surgery affects the tumor microenvironment negatively and promotes the growth of possible malignant cells remaining in the tumor bed. Objective: The present
Sepehr Torabinejad +3 more
doaj +1 more source
PurposeThe purpose of this study was to assess the effectivity of upfront kilovoltage intraoperative radiotherapy (IORT) as a boost in high-risk early-stage breast cancer patients from an international pooled cohort.Materials/MethodsPatients from four ...
Gustavo R. Sarria +20 more
doaj +1 more source
Clinical implementation of intraoperative radiotherapy
<p>Presentation describing the clinical implementation of an intraoperative radiotherapy service across two institutions.</p ...
Ferguson, Melanie +7 more
core +1 more source
Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer:5-year results for local control and overall survival from the TARGIT-a randomised trial [PDF]
Background: The TARGIT-A trial compared risk-adapted radiotherapy using single-dose targeted intraoperative radiotherapy (TARGIT) versus fractionated external beam radiotherapy (EBRT) for breast cancer.
Holtveg, Helle M R +39 more
core +1 more source
Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment [PDF]
In the randomised TARGIT-A trial, risk-adapted targeted intraoperative radiotherapy (TARGIT-IORT) during lumpectomy was non-inferior to whole-breast external beam radiotherapy, for local recurrence. In the long-term, no difference was found in any breast
Hoefer, R +47 more
core +2 more sources
Assessment of Thyroid Lobe Dose in Breast Cancer Intraoperative Radiotherapy [PDF]
Background: Breast cancer is the most common cancer among women. Considering the fact that a high dose is delivered in a single fraction of IORT, the evaluation of the dose at sensitive organs like thyroid is necessary.
R Ramezani Farkhani +3 more
doaj +1 more source
Combined modality treatment of operable breast cancer using intraoperative radiotherapy
Objective of the study: To review worldwide literature data on the efficacy of combined modality treatment including intraoperative radiation therapy (IORT) in patients with operable breast cancer (BC). Material and Мethods.
N. A. Alaichiev +7 more
doaj +1 more source
INTRABEAM: precision hypo-fractionated radiotherapy with a systemic immune response [PDF]
Purpose or Objective: To evaluate the changes in immune-cell phenotype in peripheral blood following intraoperative radiotherapy (IORT) in breast cancer ...
Pérez Montero, Héctor +8 more
core +1 more source

