Results 141 to 150 of about 1,034,952 (285)

Advances in Intraperitoneal Chemotherapy for Gastric Cancer Patients with Peritoneal Metastases: Current Status of Treatment and Institutional Insights. [PDF]

J Clin Med
Saito S, Yamaguchi H, Saito A, Kaneko Y, Ohzawa H, Yokota S, Kitayama J.   +6 more
europepmc   +1 more source

Cationic Nanoparticles Mitigate Chemotherapy‐Induced Peripheral Neuropathy

Advanced NanoBiomed Research, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN), caused by chemodrugs like paclitaxel (PTX), leads to severe neuropathic pain. This study evaluates PTX‐loaded PAMAM‐Chol nanoparticles (PTX‐NPs) to alleviate CIPN. PTX‐NPs achieve 99% drug‐loading efficiency, reduce neurotoxicity, and in murine models, decrease cold allodynia by 85% while restoring ...
Divya Bhansali, Rocco Latorre, Raquel Tonello, David Poolman, Suwan Ding, Brian L. Schmidt, Nigel W. Bunnett, Kam W. Leong   +7 more
wiley   +1 more source

Expanding the horizons of cytoreductive surgery-hyperthermic intraperitoneal chemotherapy and liver resection for colorectal peritoneal and liver metastases. [PDF]

Hepatobiliary Surg Nutr
Gohda Y, Kokudo N.
europepmc   +1 more source

The effect of sodium nitroprusside in scaffolds for synergetic gas‐photothermal therapy of osteosarcoma

BMEMat, EarlyView.
The PCLA‐SNP scaffolds can produce photothermal agents in situ under ultraviolet radiation. Then, the scaffold can release nitric oxide gas spontaneously and generate hyperthermia under near‐infrared laser to enhance ablation of bone tumors. Furthermore, the calcium and iron ions released from PCLA‐SNP scaffolds can accelerate bone regeneration ...
Shaojie Dong, Yuwei Zhang, Yukun Mei, Changjie Sun, Xingge Yu, Mazaher Gholipourmalekabadi, Kaili Lin, Lin Niu, Li Zhao, Changyong Yuan   +9 more
wiley   +1 more source

Robotic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: is there a benefit? [PDF]

Surg Endosc
Sparkman BK, Freudenberger DC, Vudatha V, Trevino JG, Khader A, Fernandez LJ.   +5 more
europepmc   +1 more source

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for gastric cancer with peritoneal metastases at an Australian centre. [PDF]

World J Surg Oncol
Hayler R, Domingos N, Ashrafizadeh A, Wijayawardana R, Ahmadi N, Liauw W, Morris D.   +6 more
europepmc   +1 more source

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Cancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo   +6 more
wiley   +1 more source

Pharmacokinetics of cisplatin in the systemic versus hyperthermic intrathoracic or intraperitoneal chemotherapy. [PDF]

Cancer Chemother Pharmacol
Zhang T, Mu W, Liao CG, Hou Y, Song J, Hu W, Wang Y, Chen D, Chen Y, Liu L, Liu L.   +10 more
europepmc   +1 more source

New National Network of Experts (Japan Pelvic Exenteration Network: J‐PEN) Formed in a Bid to Improve Outcomes of Pelvic Exenteration in Japan

Annals of Gastroenterological Surgery, EarlyView.
Hideaki Yano, Alex Mirnezami, Masataka Ikeda, Kay Uehara, Shuichiro Matoba, Yuichiro Tsukada, Toshiki Mukai, Kei Kimura, Yudai Fukui, Naoyuki Toyota   +9 more
wiley   +1 more source