Results 11 to 20 of about 1,075,882 (382)

Effect of Hyperthermic Intraperitoneal Chemotherapy on Cytoreductive Surgery in Gastric Cancer With Synchronous Peritoneal Metastases: The Phase III GASTRIPEC-I Trial

Journal of Clinical Oncology, 2023
PURPOSE In patients with peritoneal metastasis (PM) from gastric cancer (GC), chemotherapy is the treatment of choice. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are still being debated. This randomized, controlled,
B. Rau, Hauke Lang, Alfred Koenigsrainer, Ines Gockel, H. Rau, Hendrik Seeliger, Christian Lerchenmueller, D. Reim, Roger Wahba, Martin Angele, S. Heeg, Tobias Keck, Arved Weimann, Stefan Topp, P. Piso, A. Brandl, Silke Schuele, Peter Jo, J. Pratschke, Sandra Wegel, A. Rehders, N. Moosmann, J. Gaedcke, Volker Heinemann, E. Trips, Markus Loeffler, P. Schlag, P. Thuss-Patience   +27 more
semanticscholar   +1 more source

Efficacy and Safety of Intraoperative Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Colon Cancer: A Phase 3 Randomized Clinical Trial.

JAMA Surgery, 2023
Importance Peritoneal metastasis in patients with locally advanced colon cancer (T4 stage) is estimated to recur at a rate of approximately 25% at 3 years from surgical resection and is associated with poor prognosis.
Á. Arjona-Sánchez, E. Espinosa-Redondo, A. Gutiérrez-Calvo, J. Segura-Sampedro, E. Pérez-Viejo, Vanessa Concepción-Martín, S. Sánchez-García, A. García-Fadrique, I. Prieto-Nieto, P. Barrios-Sánchez, J. Torres‐Melero, M. Ramirez Faraco, A. Prada-Villaverde, J. Carrasco-Campos, M. Artiles-Armas, P. Villarejo-Campos, G. Ortega-Pérez, Emrique Boldo-Roda, J. Sánchez-Hidalgo, Á. Casado-Adam, L. Rodriguez-Ortiz, E. Aranda, M. Cano-Osuna, César Díaz-López, A. Romero-Ruiz, J. Briceño-Delgado, S. Rufián-Peña   +26 more
semanticscholar   +1 more source

Current Situation of Hyperthermic Intraperitoneal Chemotherapy in Peritoneal Carcinoma

Zhongliu Fangzhi Yanjiu, 2021
Peritoneal carcinoma is a kind of malignant tumor which occurs and develops on the peritoneum, including primary and secondary tumors. Hyperthermic intraperitoneal chemotherapy is a combined therapy of intraperitoneal perfusion, hyperthermia and ...
ZHAN Hongjie, LIANG Han
doaj   +1 more source

Survival After Hyperthermic Intraperitoneal Chemotherapy and Primary or Interval Cytoreductive Surgery in Ovarian Cancer

JAMA Surgery, 2022
Key Points Question Does hyperthermic intraperitoneal chemotherapy (HIPEC) after primary or interval cytoreductive surgery increase survival in patients with ovarian cancer?
M. Lim, Suk-Joon Chang, Boram Park, H. Yoo, C. Yoo, B. Nam, Sang-Yoon Park   +6 more
semanticscholar   +1 more source

Intraperitoneal Chemotherapy for Unresectable Peritoneal Surface Malignancies

Drugs, 2023
Malignancies of the peritoneal cavity are associated with a dismal prognosis. Systemic chemotherapy is the gold standard for patients with unresectable peritoneal disease, but its intraperitoneal effect is hampered by the peritoneal-plasma barrier ...
Niels A. D. Guchelaar, B. Noordman, S. Koolen, B. Mostert, E. Madsen, J. Burger, A. Brandt-Kerkhof, G. Creemers, I. D. de Hingh, M. Luyer, S. Bins, E. van Meerten, S. Lagarde, C. Verhoef, B. Wijnhoven, R. Mathijssen   +15 more
semanticscholar   +1 more source

The Role of Hyperthermic Intraperitoneal Chemotherapy in Pseudomyxoma Peritonei After Cytoreductive Surgery.

JAMA Surgery, 2021
Importance Studies on the prognostic role of hyperthermic intraperitoneal chemotherapy (HIPEC) in pseudomyxoma peritonei (PMP) are currently not available.
S. Kusamura, F. Barretta, Y. Yonemura, P. Sugarbaker, B. Moran, E. Levine, D. Goéré, D. Baratti, E. Nizri, D. Morris, O. Glehen, A. Sardi, P. Barrios, F. Quénet, L. Villeneuve, A. Gómez-Portilla, I. D. de Hingh, W. Ceelen, J. Pelz, P. Piso, S. González-Moreno, K. van der Speeten, M. Deraco   +22 more
semanticscholar   +1 more source

Secondary Cytoreduction and Carboplatin Hyperthermic Intraperitoneal Chemotherapy for Platinum-Sensitive Recurrent Ovarian Cancer: An MSK Team Ovary Phase II Study

Journal of Clinical Oncology, 2021
PURPOSE The purpose of this phase II study was to evaluate hyperthermic intraperitoneal chemotherapy (HIPEC) with carboplatin for recurrent ovarian cancer during secondary cytoreductive surgery.
O. Zivanovic, D. Chi, Qin C Zhou, A. Iasonos, J. Konner, V. Makker, R. Grisham, Amy K Brown, S. Nerenstone, John P Diaz, E. Schroeder, C. Langstraat, V. Paroder, Y. Lakhman, Krysten Soldan, K. Su, G. Gardner, V. Andikyan, Jianxia Guo, E. Jewell, K. L. Long Roche, T. Troso-Sandoval, S. Lichtman, L. Moukarzel, K. Dessources, N. Abu-Rustum, C. Aghajanian, W. Tew, J. Beumer, Y. Sonoda, R. O'Cearbhaill   +30 more
semanticscholar   +1 more source

Simulating drug penetration during hyperthermic intraperitoneal chemotherapy

Drug Delivery, 2021
Hyperthermic intraperitoneal chemotherapy (HIPEC) is administered to treat residual microscopic disease after debulking cytoreductive surgery. During HIPEC, a limited number of catheters are used to administer and drain fluid containing chemotherapy (41 ...
Daan R Löke, R. F. Helderman, N. Franken, A. Oei, P. Tanis, J. Crezee, H. P. Kok   +6 more
semanticscholar   +1 more source

Successful treatment of peritoneal recurrence after gastric cancer surgery with intravenous and intraperitoneal paclitaxel combined with S-1 chemotherapy: a case report

Surgical Case Reports, 2020
Background Despite recent advances in systemic chemotherapy, the prognosis of patients with peritoneal metastases from gastric cancer still remains poor.
Kozo Miyatani, Wataru Miyauchi, Yusuke Kono, Yuji Shishido, Joji Watanabe, Takehiko Hanaki, Kyoichi Kihara, Tomoyuki Matsunaga, Manabu Yamamoto, Yoji Fukumoto, Naruo Tokuyasu, Shuichi Takano, Teruhisa Sakamoto, Soichiro Honjo, Toshimichi Hasegawa, Yoshiyuki Fujiwara   +15 more
doaj   +1 more source

Drug Distribution and Penetration of Foam-Based Intraperitoneal Chemotherapy (FBIC)

Pharmaceuticals, 2023
For decades, intraperitoneal chemotherapy (IPC) was used as a liquid solution for the treatment of peritoneal metastasis. Due to its advantageous physical properties, foam-based intraperitoneal chemotherapy (FBIC) was recently proposed as a treatment for
Carolina Khosrawipour, Jakub Nicpoń, Zdzisław Kiełbowicz, Przemysław Prządka, Bartłomiej Liszka, Veria Khosrawipour, Said Al-Jundi, Shiri Li, Hien Lau, Joanna Kulas, Piotr Kuropka, Agata Diakun, Wojciech Kielan, Mariusz Chabowski, Agata Mikolajczyk-Martinez   +14 more
doaj   +1 more source