Results 21 to 30 of about 542,903 (199)

Intraperitoneal Chemotherapy for Unresectable Peritoneal Surface Malignancies [PDF]

, 2023
Malignancies of the peritoneal cavity are associated with a dismal prognosis. Systemic chemotherapy is the gold standard for patients with unresectable peritoneal disease, but its intraperitoneal effect is hampered by the peritoneal-plasma barrier ...
Creemers, G.J., Bins, S., Mathijssen, R.H.J., Lagarde, S.M., Wijnhoven, Bas P.L., Verhoef, C., Madsen, E.V.E., Guchelaar, N.A.D., Luyer, M., Creemers, Geert Jan, Koolen, Stijn L.W., Brandt-Kerkhof, A.R.M., Mathijssen, Ron H.J.; id_orcid, Brandt-Kerkhof, Alexandra R.M., van Meerten, E., Verhoef, Cornelis, Burger, Jacobus W.A., de Hingh, Ignace H.J.T., van Meerten, Esther, Koolen, S.L.W., Luyer, Misha, Burger, J.W.A., Wijnhoven, B.P.L., de Hingh, I.H.J.T., Noordman, Bo J., Noordman, B.J., Guchelaar, Niels A.D., Lagarde, Sjoerd M., Mostert, B., Bins, Sander, Madsen, Eva V.E.; id_orcid, Mostert, Bianca; id_orcid, Stijn L. W. Koolen, Geert-Jan Creemers, Sander Bins, Jacobus W. A. Burger, Ron. H. J. Mathijssen, Bianca Mostert, Ignace H. J. T. de Hingh, Niels A. D. Guchelaar, Bo J. Noordman, Eva V. E. Madsen, Alexandra R. M. Brandt-Kerkhof, Misha Luyer, Sjoerd M. Lagarde, Bas P. L. Wijnhoven, Cornelis Verhoef, Esther van Meerten   +47 more
core   +1 more source

Hyperthermic Intraperitoneal Chemotherapy: A Critical Review [PDF]

Cancers, 2021
With increasing awareness amongst physicians and improved radiological imaging techniques, the peritoneal cavity is increasingly recognized as an important metastatic site in various malignancies. Prognosis of these patients is usually poor as traditional treatment including surgical resection or systemic treatment is relatively ineffective ...
Wim Ceelen, Jesse Demuytere, Ignace de Hingh   +2 more
openaire   +5 more sources

Intraperitoneal Chemotherapy Using Fluorouracil Implants Combined With Radical Resection and Postoperative Adjuvant Chemotherapy for Stage III Gastric Cancer: A Multi-Center, Randomized, Open-Label, Controlled Clinical Study

Frontiers in Oncology, 2021
BackgroundReducing peritoneal recurrence after radical surgery is an important choice to improve the prognosis of patients with advanced gastric cancer.
Yan Xu, Rupeng Zhang, Chunfeng Li, Zhe Sun, Jingyu Deng, Xiaona Wang, Xuewei Ding, Baogui Wang, Qiang Xue, Bin Ke, Hongjie Zhan, Ning Liu, Yong Liu, Xuejun Wang, Han Liang, Yingwei Xue, Huimian Xu   +16 more
doaj   +1 more source

Intra-operative characteristics of pressurized intraperitoneal aerosol chemotherapy.

, 2023
Intra-operative characteristics of pressurized intraperitoneal aerosol chemotherapy.
Pierre-Louis Conan (17511346), Adeline Aime (17511349), Hugo Picchi (17511355), Solène Doat (15006081), Marc Pocard (3795094), Jade Fawaz (17511352), Brice Malgras (17511343), Anne-Cécile Ezanno (17511340)   +7 more
core   +1 more source

MODERN STRATEGY IN TREATMENT OF PERITONEAL CARCINOMATOSIS

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2017
Peritoneal carcinomatosis (PC) is a common manifestation of progression in peritoneal and gynecologic malignancies. Current primary strategy in treatment of PC is the concept of regional influence by the way of cytoreductive surgery and intraperitoneal ...
A. A. Zakharenko, D. A. Zaitcev, M. A. Belyaev, A. A. Trushin, O. A. Ten, A. S. Natkha, K. N. Vovin, V. A. Rybalchenko   +7 more
doaj   +1 more source

Intraperitoneal chemotherapy for gastric cancer with peritoneal carcinomatosis: is HIPEC the only answer? [PDF]

, 2014
Gastric cancer with peritoneal carcinomatosis is notorious for its dismal prognosis. While the pathophysiology of peritoneal dissemination is still controversial, the rapid downhill course is universal.
Lam, KO, Law, SYK, Kwong, DLW, Law, BTT
core   +1 more source

Gastric cancer: modern approaches and prospects of treatment for peritoneal carcinomatosis (literature review)

Сибирский онкологический журнал, 2022
Gastric cancer (gc) is one of the most common cancers worldwide. The majority of newly diagnosed gastric cancer cases present with distant metastases. Peritoneal carcinomatosis (pc) is the most unfavorable type of progression of primary gc, which occurs ...
V. A. Markovich, S. A. Tuzikov, E. O. Rodionov, N. V. Litvyakov, N. O. Popova, M. M. Tsyganov, L. V. Levonyan, S. V. Miller, D. V. Podolko, I. A. Tsydenova, M. K. Ibragimova   +10 more
doaj   +1 more source

A real-word study: is normothermic intraoperative intraperitoneal chemotherapy impactful as we expect?

Frontiers in Oncology, 2023
BackgroundPatients with gastric cancer have a poor prognosis. Currently, intraperitoneal chemotherapy has been considered a therapeutic option to improve prognosis due to its appealing theoretical rationales.
Mengyao Jin, Wei Cao, Junjie Chen, Maoming Xiong, Guodong Cao, Bo Chen, Bo Chen   +6 more
doaj   +1 more source

A Clinical Pharmacological Perspective on Intraperitoneal Chemotherapy. [PDF]

Drugs
Peritoneal metastases (PM), frequently observed in malignancies such as ovarian, colorectal, pancreatic, and gastric cancers, present a significant therapeutic challenge due to poor prognosis and limited effectiveness to systemic chemotherapy.
Rietveld PCS, Guchelaar NAD, Sassen SDT, Koch BCP, Mathijssen RHJ, Koolen SLW.   +5 more
europepmc   +2 more sources

Potential survival benefits from optimized chemotherapy implementation in advanced ovarian cancer: Projections from a microsimulation model.

PLoS ONE, 2019
BackgroundOvarian cancer is often diagnosed in advanced stages, when survival is poor. Treatment advances have been made, but are inconsistently implemented.
Anna P Lietz, Davis T Weaver, Alexander Melamed, Jose Alejandro Rauh-Hain, Jason D Wright, Alexi A Wright, Amy B Knudsen, Pari V Pandharipande   +7 more
doaj   +1 more source