Results 11 to 20 of about 542,903 (199)

Intraperitoneal Chemotherapy Strategies in Pancreatic Ductal Adenocarcinoma: A Systematic Review of Hyperthermic Intraperitoneal Chemotherapy, Normothermic Intraperitoneal Chemotherapy, and Pressurized Intraperitoneal Aerosol Chemotherapy. [PDF]

Cancers (Basel)
Background: Peritoneal metastasis represents an aggressive disease pattern in pancreatic ductal adenocarcinoma (PDAC), traditionally associated with poor survival and limited therapeutic options. Emerging intraperitoneal chemotherapy strategies—including hyperthermic intraperitoneal chemotherapy (HIPEC), normothermic intraperitoneal paclitaxel (NIPEC ...
Ganatra N, Abdelhakeem A, Jain P, Kamatham S, Elantably D, Adeoye O, Babiker HM, O'Donnell CD, Majeed U.   +8 more
europepmc   +4 more sources

Effect of intraperitoneal chemotherapy concentration on morbidity and survival [PDF]

BJS Open, 2020
Background Selected patients with colorectal peritoneal metastases are treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).
F. M. K. Elekonawo, W. J. vanEden, W. Y. van derPlas, R. S. G. Ewalds, L. A. W. deJong, A. J. A. Bremers, P. H. J. Hemmer, N. F. M. Kok, S. Kruijff, A. G. J. Aalbers, P. R. deReuver   +10 more
doaj   +2 more sources

Peritoneal carcinomatosis treated with cytoreductive surgery and intraperitoneal chemotherapy

Journal of Coloproctology, 2018
Introduction: To evaluate the combined treatment with cytoreductive surgery and intraperitoneal chemotherapy for peritoneal carcinomatosis arising from colorectal cancer, pseudomyxoma peritonei and mesothelioma.
Bernardo Hanan, Leonardo Maciel Fonseca, Magda Maria Profeta da Luz, Antônio Lacerda-Filho, Mônica Maria Demas Álvares Cabral, Rodrigo Gomes da Silva   +5 more
doaj   +3 more sources

Efficacy and safety of intraperitoneal chemotherapy for pancreatic cancer

BMC Surgery
Pancreatic cancer is a highly aggressive cancer with unfavorable prognosis despite the therapeutic interventions. Intraperitoneal chemotherapy has recently shown potential outcomes in the presence of peritoneal metastases.
Dorsa Safari, Mohammad Fakhrolmobasheri, Saeed Soleymanjahi   +2 more
doaj   +2 more sources

Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer

Diagnostics, 2020
Hyperthermic intraperitoneal chemotherapy (HIPEC) in conjunction with cytoreductive surgery (CRS) holds promise as an adjunctive treatment strategy in malignancies affecting the peritoneal surface, effectively targeting remaining microscopic residual ...
McKayla J. Riggs, Prakash K. Pandalai, Joseph Kim, Charles S. Dietrich   +3 more
doaj   +2 more sources

Investigation of the effectiveness of hyperthermic intraperitoneal chemotherapy in experimental colorectal peritoneal metastasis model

Pleura and Peritoneum, 2023
In our study, we aimed to (1) create a peritoneal metastasis (PM) model in nude mice, administer intraperitoneal chemotherapy using the peritoneal infusion pump we developed in this model, and (2) compare the efficacy of intraperitoneal chemotherapy ...
Manoğlu Berke, Yavuzşen Tuğba, Aktaş Safiye, Altun Zekiye, Yılmaz Osman, Gökbayrak Özde Elif, Erol Aylin   +6 more
doaj   +2 more sources

Anesthetic implications in hyperthermic intraperitoneal chemotherapy

Journal of Anaesthesiology Clinical Pharmacology, 2019
Patients with peritoneal carcinomatosis were considered incurable with dismal survival rates till hyperthermic intraperitoneal chemotherapy after optimal cytoreductive surgery evolved. Perioperative management for these procedures is complex and involves
Nishkarsh Gupta, Vinod Kumar, Rakesh Garg, Sachidanand Jee Bharti, Seema Mishra, Sushma Bhatnagar   +5 more
doaj   +2 more sources

Effect of hyperthermia on improving neutrophil restoration after intraperitoneal chemotherapy

International Journal of Hyperthermia, 2019
Purpose: Intraperitoneal (IP) chemotherapy has several benefits but also can have severe hematologic side effects. We compared the effects of hyperthermic intraperitoneal chemotherapy (HIPEC) and conventional IP chemotherapy on bone marrow suppression ...
Wan-Chun Huang, Chao-Chih Wu, Yun-Ting Hsu, Chih-Long Chang   +3 more
doaj   +2 more sources

Intraperitoneal Chemotherapy

International Journal of Gynecological Cancer, 2010
Objectives:Critical evaluation of the benefits of intraperitoneal (IP) chemotherapy.Methods:Critical review of the literature in support of the administration of chemotherapy via the IP route.Results:The 3 largest randomized phase III trials conducted by
Walter H. Gotlieb
openaire   +2 more sources

Adjuvant Bidirectional Chemotherapy Using an Intraperitoneal Port [PDF]

Gastroenterology Research and Practice, 2012
Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have been established as treatment options for patients with peritoneal metastases or peritoneal mesothelioma.
Paul H. Sugarbaker, Lana Bijelic
doaj   +2 more sources