Results 1 to 10 of about 381,959 (294)

Towards an optimal model for gastric cancer peritoneal metastasis: current challenges and future directions

open access: yesEBioMedicine, 2023
Summary: Peritoneal metastasis is a challenging aspect of clinical practice for gastric cancer. Animal models are crucial in understanding molecular mechanisms, assessing drug efficacy, and conducting clinical intervention studies, including those ...
Zehui Li   +3 more
doaj   +4 more sources

From Primary Tumor to Peritoneal Niche: Microenvironmental Divergence in Gastric Cancer Peritoneal Metastasis [PDF]

open access: yesCells
Gastric cancer peritoneal metastasis is not simply an extension of the primary tumor into the abdominal cavity. It represents a biologically distinct disease context shaped by interactions between disseminated tumor cells, peritoneal fluid, mesothelial ...
Catalin-Bogdan Satala   +6 more
doaj   +3 more sources

Prognostic Value of Systemic Inflammatory Markers in Predicting Peritoneal Metastasis in Gastric and Gastroesophageal Junction Cancer [PDF]

open access: yesClinical and Translational Science
Gastric cancer and gastroesophageal junction cancer, primarily adenocarcinoma, originate in the stomach's mucosa. Peritoneal metastasis is a common pattern in gastric cancer. The neutrophil‐to‐lymphocyte ratio (NLR) and platelet‐to‐lymphocyte ratio (PLR),
Mahesh Wadhwa   +5 more
doaj   +3 more sources

Advance of peritoneal metastasis of colorectal cancer

open access: yes结直肠肛门外科, 2023
Peritoneal metastasis is a common distant metastasis of colorectal cancer and it is associated with poor prognosis. While previously peritoneal metastasis of colorectal cancer is considered a terminal stage of the disease.
Zhou Shiqi, Zhu Yuping
doaj   +2 more sources

Progress in application of peritoneal lavage fluid circulating tumor DNA to predicting peritoneal metastasis of gastrointestinal cancer [PDF]

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Peritoneal metastasis is one of the important causes of death in patients with gastrointestinal cancer and is also a difficult point in clinical diagnosis and treatment.
BAI Long   +3 more
doaj   +2 more sources

Predictors of peritoneal metastasis of gastric origin

open access: yesJournal of the Egyptian National Cancer Institute, 2022
Background Gastric adenocarcinoma is one of the most aggressive forms of cancer. Despite marked advancements in radiological techniques, peritoneal deposits are still only discovered during laparotomies in a significant number of cases.
Mohamed Atef ElKordy   +4 more
doaj   +3 more sources

Preoperative clinical-imaging nomogram for peritoneal metastasis in gastric cancer: a retrospective cohort study [PDF]

open access: yesBMC Gastroenterology
Objective To explore the preoperative predictive factors for peritoneal metastasis in patients with advanced gastric cancer and construct a nomogram prediction model combining clinical and radiomics features. Methods A total of 342 patients with advanced
Suxia Qi, Hong Zhang, Yongzhi Lu
doaj   +2 more sources

CXCL8 and the peritoneal metastasis of ovarian and gastric cancer

open access: yesFrontiers in Immunology, 2023
CXCL8 is the most representative chemokine produced autocrine or paracrine by tumor cells, endothelial cells and lymphocytes. It can play a key role in normal tissues and tumors by activating PI3K-Akt, PLC, JAK-STAT, and other signaling pathways after ...
Xuanrong Fu   +3 more
doaj   +3 more sources

Animal models of colorectal peritoneal metastasis

open access: yesPleura and Peritoneum, 2016
Abstract Colorectal cancer remains an important cause of mortality worldwide. The presence of peritoneal carcinomatosis (PC) causes significant symptoms and is notoriously difficult to treat. Therefore, informative preclinical research into the mechanisms and possible novel treatment options of colorectal PC is essential in order to ...
Wim Ceelen, Wouter Willaert
exaly   +3 more sources

Factors Affecting Positive Peritoneal Lavage Cytology in Patients with Stage II and III Colorectal Cancer with R0 Resection: A Multi-institutional, Prospective Study

open access: yesJournal of the Anus, Rectum and Colon, 2021
Objectives: This study aimed to explore the risk factors associated with cancer cell exfoliation in Stage II and III colorectal cancer (CRC). Methods: This multicenter, prospective, observational study targeted 1,698 patients with cStage II and III CRC ...
Harunobu Sato   +5 more
doaj   +1 more source

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