Results 31 to 40 of about 381,959 (294)

MiR-136 inhibits gastric cancer–specific peritoneal metastasis by targeting HOXC10

Tumor Biology, 2017
Functions of microRNAs have been characterized in the embryologic, physiologic, and oncogenic processes, but the role of microRNAs in mediating tumor-specific organ metastasis was addressed only recently and still absent in gastric cancer peritoneal ...
Jianyong Zheng, Peng Ge, Xiaonan Liu, Jiangpeng Wei, Guosheng Wu, Xiaohua Li   +5 more
doaj   +1 more source

A Case of Peritoneal Dissemination and Splenic Metastasis after Gastric Cancer Surgery That Could Be Controlled with Multidisciplinary Treatment

Case Reports in Oncology, 2020
Splenic metastasis is known to occur at the terminal stage of cancer. While peritoneal dissemination is the most frequent recurrence of gastric cancer, metastasis to the spleen from gastric cancer is very rare. Splenectomy is currently the most effective
Nozomi Karakuchi, Senichiro Yanagawa, Daisuke Takei, Shinya Kodama, Yukio Takeshima, Kazuo Sumimoto   +5 more
doaj   +1 more source

Modulation of p53 expression in cancer-associated fibroblasts prevents peritoneal metastasis of gastric cancer

Molecular Therapy: Oncolytics, 2022
Cancer-associated fibroblasts (CAFs) in the tumor microenvironment are associated with the establishment and progression of peritoneal metastasis. This study investigated the efficacy of replicative oncolytic adenovirus-mediated p53 gene therapy (OBP-702)
Toshihiro Ogawa, Satoru Kikuchi, Motoyasu Tabuchi, Ema Mitsui, Yuta Une, Hiroshi Tazawa, Shinji Kuroda, Kazuhiro Noma, Toshiaki Ohara, Shunsuke Kagawa, Yasuo Urata, Toshiyoshi Fujiwara   +11 more
doaj   +1 more source

Establishment and Characterization of Paired Primary and Peritoneal Seeding Human Colorectal Cancer Cell Lines: Identification of Genes That Mediate Metastatic Potential

Translational Oncology, 2018
Peritoneal metastasis is one of the major patterns of unresectability in colorectal cancer (CRC) and a cause of death in advanced CRC. Identification of distinct gene expressions between primary CRC and peritoneal seeding metastasis is to predict the ...
Soon-Chan Kim, Chang-Won Hong, Sang-Geun Jang, Ye-Ah Kim, Byong-Chul Yoo, Young-Kyoung Shin, Seung-Yong Jeong, Ja-Lok Ku, Jae-Gahb Park   +8 more
doaj   +1 more source

Obesity promotes gastric cancer metastasis via diacylglycerol acyltransferase 2-dependent lipid droplets accumulation and redox homeostasis

Redox Biology, 2020
Experimental and molecular epidemiological studies indicate important roles for adipose tissue or high-fat diet (HFD) in tumor growth and metastasis. Gastric cancer (GC) possesses a metastatic predilection for the adipocyte-rich peritoneum.
Shuai Li, Teng Wu, Yun-Xin Lu, Jin-Xiang Wang, Feng-Hai Yu, Mei-Zhu Yang, Yi-Jia Huang, Zhi-Jing Li, Sen-Lan Wang, Ling Huang, Lei Lu, Tian Tian   +11 more
doaj   +1 more source

Late peritoneal metastasis in a patient with osteosarcoma

Annals of Oncology, 1998
A 19-year-old man with a high-grade osteosarcoma of the femur, treated with neoadjuvant chemotherapy, surgery, and adjuvant chemotherapy suffered from lung metastases 15 months after diagnosis. They were resected. Thirteen months later, he had vague abdominal complaints which, after analysis, proved to be caused by peritoneal metastasis.
Westra, A., Schrijvers, D., Somville, J., Van Schil, P., Hubens, G., van Oosterom, A.   +5 more
openaire   +3 more sources

Peritoneal and gastric metastasis from invasive lobular breast carcinoma: a case report [PDF]

Kosin Medical Journal, 2015
Peritoneal and gastrointestinal metastasis from breast cancer is very rare. We report here a rare case of metastatic peritoneal and gastric cancer from breast lobular carcinoma after modified radical mastectomy.
Yoon Seok Kim, Eun Ae Jae, Dong Won Ryu, Chung Han Lee   +3 more
doaj   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. [PDF]

, 2012
Mesothelial cells are critical in the pathogenesis of post-surgical intraabdominal adhesions as well as in the deterioration of the peritoneal membrane associated with long-term peritoneal dialysis.
Elfriede Noessner, Susan Notohamiprodjo, Pankaj Goyal, Sauter, M., Sitter, T., Sitter, Thomas, Markus Wörnle, Andrea Ribeiro, Peter J. Nelson (168215), Thomas Sitter, Matthias Sauter (168187), Wolfgang Siess, Wolfgang Siess (168198), Susanne Himmelein, Nelson, P.J., Himmelein, Susanne, Thomas Sitter (168211), Goyal, P., Sauter, Matthias, Susanne Himmelein (168206), Nelson, Peter J., Markus Wörnle (168201), Susan Notohamiprodjo (168192), Ribeiro, A., Notohamiprodjo, Susan, Elfriede Noessner (146689), Noessner, Elfriede, Wörnle, Markus, Djafarzadeh, Roghieh, Roghieh Djafarzadeh, Matthias Sauter, Nößner, E., Andrea Ribeiro (168203), Roghieh Djafarzadeh (88033), Himmelein, S., Peter J Nelson, Wörnle, M., Goyal, Pankaj, Ribeiro, Andrea, Djafarzadeh, R., Notohamiprodjo, S., Pankaj Goyal (156516), Siess, W., Siess, Wolfgang   +43 more
core   +2 more sources

Genomic landscape of paired primary and peritoneal metastatic lesions in gastric cancer highlights evolutionary dynamics and mutational drivers

Journal of Advanced Research
Introduction: Peritoneal metastasis is a prevalent form of gastric cancer spread, often resulting in poor outcomes. Due to the lack of clinical recommendation for surgery, current omics studies are limited to analyzing suspending malignant cells in ...
Song Li, Weiwei Zhang, Qian Yang, Shuhan Li, Xuanyu Zhou, Huan Wang, Ying Sun, Xiangyong Liu, Chunwang Ji, Jianyuan Zhou, Shulun Nie, Xuehui Wu, Jianqiao Jiao, Liliang Dou, Qinqin Hu, Fan Jiang, Qian Xu, Xin Dai, Zhaodi Nan, Xinyu Song, Di Zhang, Wen Zhao, Shuang Wang, Jiahui Chu, Lian Liu   +24 more
doaj   +1 more source