Results 21 to 30 of about 62,247 (257)

Primary Peritoneal Carcinosarcoma With Metastasis to the Umbilicus and Pancreas [PDF]

Cureus, 2022
A 51-year-old woman visited our hospital after being diagnosed with ascites effusion by her previous physician due to weight gain for 6 months. Ascites cytology showed adenocarcinoma, MRI showed an omental cake, and CT showed neoplastic lesions in the umbilicus and pancreas. Laparoscopy revealed that the omentum had been replaced by a tumor.
Tanabe, Shohei, Sugino, Sachiyo, Ichida, Kotaro, Niiya, Kiyoshi, Morishima, Syuji   +4 more
openaire   +2 more sources

PN3b as an independent risk factor for poor prognosis and peritoneal recurrence in Borrmann type IV gastric cancer: A retrospective cohort study

Frontiers in Surgery, 2022
BackgroundThe clinicopathological features and surgical treatment strategies of Borrmann type IV gastric cancer (GC) remain controversial. Peritoneal metastasis is the most common recurrence pattern in patients with Borrmann type IV GC.MethodsAmong 2026 ...
Yiran Chen, Yanyan Chen, Liping Wen, Laizhen Tou, Haiyong Wang, Lisong Teng   +5 more
doaj   +1 more source

MiR-136 inhibits gastric cancer–specific peritoneal metastasis by targeting HOXC10

Tumor Biology, 2017
Functions of microRNAs have been characterized in the embryologic, physiologic, and oncogenic processes, but the role of microRNAs in mediating tumor-specific organ metastasis was addressed only recently and still absent in gastric cancer peritoneal ...
Jianyong Zheng, Peng Ge, Xiaonan Liu, Jiangpeng Wei, Guosheng Wu, Xiaohua Li   +5 more
doaj   +1 more source

A Case of Peritoneal Dissemination and Splenic Metastasis after Gastric Cancer Surgery That Could Be Controlled with Multidisciplinary Treatment

Case Reports in Oncology, 2020
Splenic metastasis is known to occur at the terminal stage of cancer. While peritoneal dissemination is the most frequent recurrence of gastric cancer, metastasis to the spleen from gastric cancer is very rare. Splenectomy is currently the most effective
Nozomi Karakuchi, Senichiro Yanagawa, Daisuke Takei, Shinya Kodama, Yukio Takeshima, Kazuo Sumimoto   +5 more
doaj   +1 more source

Modulation of p53 expression in cancer-associated fibroblasts prevents peritoneal metastasis of gastric cancer

Molecular Therapy: Oncolytics, 2022
Cancer-associated fibroblasts (CAFs) in the tumor microenvironment are associated with the establishment and progression of peritoneal metastasis. This study investigated the efficacy of replicative oncolytic adenovirus-mediated p53 gene therapy (OBP-702)
Toshihiro Ogawa, Satoru Kikuchi, Motoyasu Tabuchi, Ema Mitsui, Yuta Une, Hiroshi Tazawa, Shinji Kuroda, Kazuhiro Noma, Toshiaki Ohara, Shunsuke Kagawa, Yasuo Urata, Toshiyoshi Fujiwara   +11 more
doaj   +1 more source

Peritoneal Metastasis: Current Status and Treatment Options [PDF]

Cancers, 2021
Peritoneal metastasis (PM) originating from gastrointestinal cancer was considered a terminal disease until recently. The advent of better systemic treatment, a better understanding of prognostic factors, and finally, the advent of novel loco-regional therapies, has opened the door for the multimodal treatment of PM. These strategies, including radical
Roth, Lilian, Russo, Linda, Ulugoel, Sima, dos Santos, Rafael Freire, Breuer, Eva, Gupta, Anurag, Lehmann, Kuno   +6 more
openaire   +3 more sources

Establishment and Characterization of Paired Primary and Peritoneal Seeding Human Colorectal Cancer Cell Lines: Identification of Genes That Mediate Metastatic Potential

Translational Oncology, 2018
Peritoneal metastasis is one of the major patterns of unresectability in colorectal cancer (CRC) and a cause of death in advanced CRC. Identification of distinct gene expressions between primary CRC and peritoneal seeding metastasis is to predict the ...
Soon-Chan Kim, Chang-Won Hong, Sang-Geun Jang, Ye-Ah Kim, Byong-Chul Yoo, Young-Kyoung Shin, Seung-Yong Jeong, Ja-Lok Ku, Jae-Gahb Park   +8 more
doaj   +1 more source

Obesity promotes gastric cancer metastasis via diacylglycerol acyltransferase 2-dependent lipid droplets accumulation and redox homeostasis

Redox Biology, 2020
Experimental and molecular epidemiological studies indicate important roles for adipose tissue or high-fat diet (HFD) in tumor growth and metastasis. Gastric cancer (GC) possesses a metastatic predilection for the adipocyte-rich peritoneum.
Shuai Li, Teng Wu, Yun-Xin Lu, Jin-Xiang Wang, Feng-Hai Yu, Mei-Zhu Yang, Yi-Jia Huang, Zhi-Jing Li, Sen-Lan Wang, Ling Huang, Lei Lu, Tian Tian   +11 more
doaj   +1 more source

Animal models of colorectal peritoneal metastasis

Pleura and Peritoneum, 2016
Abstract Colorectal cancer remains an important cause of mortality worldwide. The presence of peritoneal carcinomatosis (PC) causes significant symptoms and is notoriously difficult to treat. Therefore, informative preclinical research into the mechanisms and possible novel treatment options of colorectal PC is essential in order to ...
Félix, Gremonprez, Wouter, Willaert, Wim, Ceelen   +2 more
openaire   +2 more sources

Peritoneal and gastric metastasis from invasive lobular breast carcinoma: a case report [PDF]

Kosin Medical Journal, 2015
Peritoneal and gastrointestinal metastasis from breast cancer is very rare. We report here a rare case of metastatic peritoneal and gastric cancer from breast lobular carcinoma after modified radical mastectomy.
Yoon Seok Kim, Eun Ae Jae, Dong Won Ryu, Chung Han Lee   +3 more
doaj   +1 more source