Results 11 to 20 of about 860,333 (340)

Molecular mediators of peritoneal metastasis in pancreatic cancer [PDF]

Cancer and Metastasis Reviews, 2020
AbstractPancreatic cancer is the third leading cause of cancer death in the USA, and pancreatic ductal adenocarcinoma (PDA) constitutes 85% of pancreatic cancer diagnoses. PDA frequently metastasizes to the peritoneum, but effective treatment of peritoneal metastasis remains a clinical challenge. Despite this unmet need, understanding of the biological
Leela Rani Avula, Brendan Hagerty, Christine Alewine   +2 more
openaire   +4 more sources

Blood ctDNA-specific markers predict the risk of peritoneal metastasis for advanced gastric cancer [PDF]

Discover Oncology
Objective The aim of this study was to investigate the value of early postoperative ctDNA dynamic monitoring (TP53/KRAS/PIK3CA gene mutations) combined with clinicopathologic factors in risk stratification of postoperative peritoneal metastasis in ...
FangZhou Xing, JunYing Shi, Ying Mu, PengYu Jiang, WeiHong Sun, ChunWei Peng   +5 more
doaj   +2 more sources

Small peritoneal macrophages are accelerators of peritoneal metastasis of colorectal cancer. [PDF]

Transl Cancer Res
The peritoneal cavity (PerC) constitutes a distinct anatomical compartment that harbors various subpopulations of peritoneal macrophages. However, there remains a significant gap in our understanding of the functions of these macrophage subpopulations in the context of peritoneal metastasis of colorectal cancer (PM-CRC) and their roles in the tumor ...
Yang W, Jiang F, Xu L, Pang N, Yang C, Yu R, Chen H.   +6 more
europepmc   +3 more sources

Factors Affecting Positive Peritoneal Lavage Cytology in Patients with Stage II and III Colorectal Cancer with R0 Resection: A Multi-institutional, Prospective Study

Journal of the Anus, Rectum and Colon, 2021
Objectives: This study aimed to explore the risk factors associated with cancer cell exfoliation in Stage II and III colorectal cancer (CRC). Methods: This multicenter, prospective, observational study targeted 1,698 patients with cStage II and III CRC ...
Harunobu Sato, Kenjiro Kotake, Kotaro Maeda, Hirotoshi Kobayashi, Hiroshi Takahashi, Kenichi Sugihara   +5 more
doaj   +1 more source

Progress in application of peritoneal lavage fluid circulating tumor DNA to predicting peritoneal metastasis of gastrointestinal cancer

Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Peritoneal metastasis is one of the important causes of death in patients with gastrointestinal cancer and is also a difficult point in clinical diagnosis and treatment.
BAI Long, XIA Xiang, CAO Hui, ZHANG Zizhen   +3 more
doaj   +1 more source

Advance of peritoneal metastasis of colorectal cancer

结直肠肛门外科, 2023
Peritoneal metastasis is a common distant metastasis of colorectal cancer and it is associated with poor prognosis. While previously peritoneal metastasis of colorectal cancer is considered a terminal stage of the disease.
Zhou Shiqi, Zhu Yuping
doaj   +1 more source

Single-cell sequencing of ascites fluid illustrates heterogeneity and therapy-induced evolution during gastric cancer peritoneal metastasis

Nature Communications, 2023
Peritoneal metastasis is one of the most common forms of death for gastrointestinal cancers, however, its cell composition is incompletely understood. Here, the authors use single cell RNA-seq of peritoneal metastases from 35 patients and show diversity ...
Xuan-Zhang Huang, Min-Jiao Pang, Jia-yi Li, Han-Yu Chen, Jingxu Sun, Yongxi Song, Hong Ni, S. Ye, Shi Bai, Teng-Hui Li, Xin-yu Wang, Jing-Yuan Lu, Jinjie Yang, Xun Sun, J. Mills, Z. Miao, Zhen-Ning Wang   +16 more
semanticscholar   +1 more source

Establishment of a patient-derived orthotopic Xenograft (PDOX) model of HER-2-positive cervical cancer expressing the clinical metastatic pattern. [PDF]

, 2015
Squamous cell carcinoma of the cervix, highly prevalent in the developing world, is often metastatic and treatment resistant with no standard treatment protocol.
Bouvet, Michael, Chishima, Takashi, Endo, Itaru, Hiroshima, Yukihiko, Hoffman, Robert M, Ichikawa, Yasushi, Maawy, Ali, Mii, Sumiyuki, Miwa, Shinji, Momiyama, Masashi, Murakami, Takashi, Murata, Takuya, Tanaka, Kuniya, Uehara, Fuminari, Yamamoto, Mako, Yano, Shuya, Zhang, Nan, Zhang, Yong   +17 more
core   +10 more sources

MiR-216b inhibits gastric cancer proliferation and migration by targeting PARK7

Indian Journal of Pathology and Microbiology, 2021
Objective: Postoperative recurrence and metastasis of gastric cancer is still a difficult problem in medical field. About 60% of patients with advanced gastric cancer die from peritoneal metastasis, which has become one of the main causes of death of ...
Guo-Min Zhu, Shao-Qin Chen, Qun-Guang Jiang, Yi Cao, Yi Guo, Li-Qin Ye   +5 more
doaj   +1 more source

Omental cancer‐associated fibroblast‐derived exosomes with low microRNA‐29c‐3p promote ovarian cancer peritoneal metastasis

Cancer Science, 2023
Ovarian cancer (OC) is characterized by frequent widespread peritoneal metastasis. Cancer‐associated fibroblasts (CAFs) represent a critical stromal component of metastatic niche and promote omentum metastasis in OC patients.
Qing Han, Shuran Tan, Lanqing Gong, Guoqing Li, Qiulei Wu, Le Chen, Shi Du, Wenhan Li, Xiao-lei Liu, Jing Cai, Zehua Wang   +10 more
semanticscholar   +1 more source