Results 51 to 60 of about 860,333 (340)

EIF4E regulates STEAP1 expression in peritoneal metastasis [PDF]

open access: yesJournal of Cancer, 2020
Gastric cancer is the most prominent form of malignancy in China, and the high mortality associated with it is mostly due to peritoneal metastasis. We have previously elucidated that the RNA-binding protein poly r(C) binding protein 1 (PCBP1) and miR-3978 function as repressors of peritoneal metastasis, partially by downregulation of six-transmembrane ...
Jiang, Jun-nan   +3 more
openaire   +2 more sources

Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance. [PDF]

open access: yes, 2018
Expression of the chromatin-associated protein HMGA2 correlates with progression, metastasis and therapy resistance in pancreatic ductal adenocarcinoma (PDAC). Hmga2 has also been identified as a marker of a transient subpopulation of PDAC cells that has
Chiou, Shin-Heng   +7 more
core   +1 more source

EZH2-H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis

open access: yesbioRxiv, 2021
Triple Negative Breast Cancer (TNBC) is known to have poor prognosis and adverse clinical outcome among all breast cancer subtypes due to the absence of available targeted therapy for it. Emerging literature indicates that epigenetic reprogramming is now
A. Verma   +6 more
semanticscholar   +1 more source

Natural killer (NK) cells and their involvement in different types of cancer. Current status of clinical research [PDF]

open access: yes, 2017
Natural killer cells are the main agents of innate immunity. Since 1970, various studies have repeatedly confirmed their involvement in decreasing local tumor growth and also decreasing the risk of metastasis, due to their cytotoxic effects and also ...
Moldovan, Adina D.   +2 more
core   +8 more sources

Medical treatment of early stage and rare histological variants of epithelial ovarian cancer [PDF]

open access: yes, 2015
Epithelial ovarian cancer is often considered a single pathological entity, but increasing evidence suggests that it is rather a group of different neoplasms, each with unique pathological characteristics, molecular features, and clinical behaviours ...
Biglia, Nicoletta   +6 more
core   +3 more sources

Hypoxia-Induced CD36 Expression in Gastric Cancer Cells Promotes Peritoneal Metastasis via Fatty Acid Uptake

open access: yesAnnals of Surgical Oncology, 2022
Background The lipid scavenger receptor cluster of differentiation 36 (CD36) has been shown to have a pro-metastatic function in several cancers. Adipose tissue, a favorable site for peritoneal metastasis (PM) from gastric cancer (GC), promotes this ...
Tatsuya Aoki   +12 more
semanticscholar   +1 more source

Animal models of colorectal peritoneal metastasis

open access: yesPleura and Peritoneum, 2016
AbstractColorectal cancer remains an important cause of mortality worldwide. The presence of peritoneal carcinomatosis (PC) causes significant symptoms and is notoriously difficult to treat. Therefore, informative preclinical research into the mechanisms and possible novel treatment options of colorectal PC is essential in order to improve the ...
Félix, Gremonprez   +2 more
openaire   +2 more sources

A PD-L1-targeting chimeric switch receptor enhances efficacy of CAR-T cell for pleural and peritoneal metastasis

open access: yesSignal Transduction and Targeted Therapy, 2022
Pleural and peritoneal metastasis accompanied by malignant pleural effusion (MPE) or malignant ascites (MA) is frequent in patients with advanced solid tumors that originate from the lung, breast, gastrointestinal tract and ovary.
Qizhi Ma   +25 more
semanticscholar   +1 more source

New views on pathogenesis and diagnosis of peritoneal carcinomatosis

open access: yesКреативная хирургия и онкология, 2023
Peritoneal metastasis occurs in a number of heterogeneous tumors originating from the ovaries, stomach, intestines, pancreas, lungs, breast, and melanoma. Peritoneal carcinomatosis significantly reduces overall survival.
K. R. Ishmuratova, K. Sh. Gantsev
doaj   +1 more source

Peritoneal and gastric metastasis from invasive lobular breast carcinoma: a case report [PDF]

open access: yesKosin Medical Journal, 2015
Peritoneal and gastrointestinal metastasis from breast cancer is very rare. We report here a rare case of metastatic peritoneal and gastric cancer from breast lobular carcinoma after modified radical mastectomy.
Yoon Seok Kim   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy