Results 71 to 80 of about 381,959 (294)

The Malta experience : a retrospective study of two types of peritoneal dialysis catheters [PDF]

, 2011
Aim: The aim of this retrospective study was to compare the one year and two year survival rate of the double cuff coiled Tenchkoff catheter (TC) and the double cuff coiled Swan Neck (SN) catheter.
Sultana, Angela, Schembri, Mark
core  

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

Advanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang   +9 more
wiley   +1 more source

Redefining the Role of Splenectomy in Scirrhous Gastric Cancer: Toward a Selective Multimodal Strategy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Scirrhous gastric cancer, characterized by diffuse infiltration and a high propensity for peritoneal dissemination, remains one of the most aggressive subtypes of gastric cancer. Despite a relatively high incidence of splenic hilar lymph node (No. 10) metastasis, the oncologic benefit of splenectomy remains controversial, while its association
Tsutomu Hayashi, Takaki Yoshikawa
wiley   +1 more source

Small peritoneal macrophages are accelerators of peritoneal metastasis of colorectal cancer

Translational Cancer Research
The peritoneal cavity (PerC) constitutes a distinct anatomical compartment that harbors various subpopulations of peritoneal macrophages. However, there remains a significant gap in our understanding of the functions of these macrophage subpopulations in the context of peritoneal metastasis of colorectal cancer (PM-CRC) and their roles in the tumor ...
Yang, Wanli, Jiang, Feng, Xu, Lixia, Pang, Nan, Yang, Chao, Yu, Ruihua, Chen, Haiqun   +6 more
openaire   +2 more sources

Basement membrane-rich Organoids with functional human blood vessels are permissive niches for human breast cancer metastasis [PDF]

, 2013
Metastasic breast cancer is the leading cause of death by malignancy in women worldwide. Tumor metastasis is a multistep process encompassing local invasion of cancer cells at primary tumor site, intravasation into the blood vessel, survival in systemic ...
David Sánchez-Martín (264504), Luis Alvarez-Vallina, Ana M Alvarez-Méndez, Álvarez-Cienfuegos, Ana, Rojo, Federico, Ángel M. Cuesta (157092), Fernández-Periáñez, Rodrigo, Álvarez-Méndez, Ana M., Laura Sanz, Vanesa Alonso-Camino (157099), Luis Álvarez-Vallina (7509), Ana Álvarez-Cienfuegos (157105), Compte, Marta, Irene Guijarro-Muñoz, Rodrigo Fernández-Periáñez, Cuesta, Ángel M., Cuesta Martínez, Ángel, Vanesa Alonso-Camino, Molina-Privado, Irene, Marta Compte (7506), Irene Molina-Privado (443574), Álvarez-Vallina, Luis, Ana Alvarez-Cienfuegos, Sandra Zazo (443575), Irene Guijarro-Muñoz (157085), Alonso-Camino, Vanesa, Sánchez-Martín, David, Rodrigo Fernández-Periáñez (443573), Zazo, Sandra, Angel M Cuesta, Laura Sanz (157117), David Sánchez-Martín, Federico Rojo, Irene Molina-Privado, Federico Rojo (163971), Sandra Zazo, Ana M. Álvarez-Méndez (443576), Guijarro-Muñoz, Irene, Sanz, Laura, Marta Compte, Rojo Todo, Federico Gustavo   +40 more
core   +1 more source

Carcinoembryonic Antigen Messenger RNA in Pelvic Lavage Fluid Predicts Local Recurrence After Curative‐Intent Resection of Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
Pelvic lavage carcinoembryonic antigen (CEA) mRNA was quantified in 178 patients undergoing curative‐intent resection for rectal cancer. Positive pelvic lavage CEA mRNA was significantly associated with local recurrence and provided additional prognostic information beyond circumferential resection margin (CRM) status.
Hiroyuki Asai, Yushi Yamakawa, Kazuyoshi Shiga, Shuhei Uehara, Akira Kato, Takuya Suzuki, Hajime Ushigome, Hiroki Takahashi, Yoichi Matsuo, Shuji Takiguchi   +9 more
wiley   +1 more source

Single-cell RNA-seq analysis of cancer-endothelial cell interactions in primary tumor and peritoneal metastasis from a single patient with colorectal cancer

BJC Reports
Background Peritoneal metastasis, a major complication of colorectal cancer (CRC), often leads to poor quality of life and unfavorable outcomes. Despite numerous studies characterizing its biological features in CRC, intratumor heterogeneity and ...
Yuri Sakimoto, Kohei Kumegawa, Shimpei Matsui, Tomohiro Yamaguchi, Toshiki Mukai, Koji Okabayashi, Seiichi Mori, Yuko Kitagawa, Takashi Akiyoshi, Reo Maruyama   +9 more
doaj   +1 more source

Impact of Histopathological Response on Outcomes After Surgical Resection Following Carbon‐Ion Radiotherapy for Pancreatic Cancer With Arterial Involvement

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Carbon‐ion radiotherapy (CIRT) provides superior dose distribution and higher biological effectiveness than conventional X‐ray radiotherapy and has emerged as a promising component of multidisciplinary treatment for advanced pancreatic ductal adenocarcinoma (PDAC).
Kenichiro Araki, Norio Kubo, Yuhei Miyasaka, Hayato Ikota, Ryo Muranushi, Mariko Tsukagoshi, Takamichi Igarashi, Masahiko Okamoto, Tatsuya Ohno, Ken Shirabe   +9 more
wiley   +1 more source

Impact of Postoperative Infectious Complications on Long‐Term Survival After Curative Resection for Colorectal Cancer: A Multicenter Study in the Minimally Invasive Era

Annals of Gastroenterological Surgery, EarlyView.
Postoperative infectious complications (PICs) have been associated with poor long‐term outcomes after colorectal cancer surgery, but evidence in the modern minimally invasive era remains limited. In this multicenter cohort of 5377 patients undergoing curative resection, PICs were independently associated with worse overall survival and relapse‐free ...
Takehito Yamamoto, Ryosuke Mizuno, Yoshiro Itatani, Tetsuya Shiota, Masahiro Yamada, Tadayoshi Yamaura, Mami Yoshitomi, Kazutaka Obama   +7 more
wiley   +1 more source