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Comparison of Cytoreductive Surgery and Resection of Isolated Peritoneal Metastases in Patients with Peritoneal Metastases from Colorectal Cancer: A Retrospective Study [PDF]
Journal of the Anus, Rectum and Colon, 2023 Objectives: This study aimed to compare the short and long-term outcomes of cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy and resection of isolated peritoneal metastases in patients with peritoneal metastases from colorectal cancer
Shinya Yoshida +7 more
doaj +3 more sources
Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice [PDF]
Journal for ImmunoTherapy of Cancer, 2022 Background The immunogenic nature of metastatic colorectal cancer (CRC) with high microsatellite instability (MSI-H) underlies their responsiveness to immune checkpoint blockade (ICB).
Onno Kranenburg +13 more
doaj +2 more sources
The CONVERGENCE trial protocol: a phase II/III trial for conversion surgery for gastric cancer with peritoneal metastases [PDF]
BMC CancerBackground The benefit of surgical resection in addition to systemic therapy in patients with gastric/gastroesophageal cancer and peritoneal metastases (GCPM) is controversial.
Daryl KA Chia +44 more
doaj +2 more sources
Characterization of collagen profile in peritoneal metastases of colorectal cancer [PDF]
Scientific ReportsThe tumor microenvironment (TME) plays a critical role in cancer progression and response to treatment. In colorectal cancer (CRC), a collagen-rich extracellular matrix (ECM) is a well-established feature of primary tumors and liver metastases.
P. Villarejo-Campos +8 more
doaj +2 more sources
Long-term control of peritoneal metastases following claudin 18.2-targeted CAR T-Cell therapy in advanced gastric cancer [PDF]
Journal of Hematology & OncologyGastric cancer with peritoneal metastasis has a poor prognosis and limited treatment options. Claudin 18.2 (CLDN18.2) CAR T therapy has shown activity in advanced gastric cancer, but its role in peritoneal disease remains insufficiently characterized ...
Chang Liu +11 more
doaj +2 more sources
Annals of Gastroenterological Surgery, 2023 Aim To establish a new Japanese classification of synchronous peritoneal metastases from colorectal cancer. Methods This multi‐institutional, prospective, observational study enrolled patients who underwent surgery for colorectal cancer with synchronous ...
Hirotoshi Kobayashi +30 more
doaj +1 more source
Frontiers in Immunology, 2022 BackgroundThe specific efficacy of immunotherapy for patients with liver metastases of gastric cancer is unclear. This study set out to explore the treatment response and related prognostic factors for patients with liver metastases of gastric cancer ...
Huayuan Liang +11 more
doaj +1 more source
Surgical Case Reports, 2020 Background Despite recent progress in systemic chemotherapy, the prognosis of patients with peritoneal metastases from gastric cancer is still poor.
Yoshiyuki Meguro +11 more
doaj +1 more source
Frontiers in Oncology, 2022 BackgroundTo date, the value of hyperthermic intraperitoneal chemotherapy (HIPEC) following up-front resection for isolated synchronous colorectal peritoneal metastases seems controversial.Patients and MethodsThis retrospective cohort study was conducted
Xiusen Qin +11 more
doaj +1 more source
Zhongliu Fangzhi Yanjiu, 2020 Peritoneum is the common site of colorectal cancer (CRC) metastasis. Female CRC patients with peritoneal metastases are often accompanied by ovarian metastases. It is generally believed that female colorectal cancer with peritoneal and ovarian metastases
CHEN Chao +6 more
doaj +1 more source