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The prognostic value of peritoneal metastases in patients with gastric cancer: a nationwide population-based studyResearch in context [PDF]

EClinicalMedicine
Summary: Background: The peritoneum is a common metastatic site in gastric cancer. The prognosis of synchronous peritoneal metastases compared to other metastatic sites in gastric cancer remains understudied.
Niels A.D. Guchelaar, Micha J. de Neijs, Bo J. Noordman, Heilida E.C. Graaf, Irene E.G. van Hellemond, Pieter C. van der Sluis, Esther Oomen-de Hoop, Sjoerd M. Lagarde, Rob H.A. Verhoeven, Stijn L.W. Koolen, Misha D.P. Luyer, Ignace H.J.T. de Hingh, Hanneke W.M. van Laarhoven, Bianca Mostert, Bas P.L. Wijnhoven, Ron H.J. Mathijssen   +15 more
doaj   +3 more sources

Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Journal for ImmunoTherapy of Cancer, 2022
Background The immunogenic nature of metastatic colorectal cancer (CRC) with high microsatellite instability (MSI-H) underlies their responsiveness to immune checkpoint blockade (ICB).
Onno Kranenburg, Hergen Spits, Julien Villaudy, Madalina Cercel, Miriam Koopman, Cornelis J A Punt, Jamila Laoukili, Andre Verheem, Inne H M Borel Rinkes, Emre Küçükköse, Balthasar A Heesters, Susan van Hal, Sylvia F Boj, Jeanine M L Roodhart   +13 more
doaj   +2 more sources

Gastric Cancer with Peritoneal Metastases: Current Status and Prospects for Treatment

Cancers, 2023
Simple Summary Peritoneal metastases from gastric cancer have a poor prognosis. Their presence usually indicates the end-stage of the disease without curative treatment.
Estibalitz Perez Viejo, Fernando Pereira, Israel Manzanedo   +2 more
exaly   +2 more sources

The Burden of Peritoneal Metastases from Gastric Cancer: A Systematic Review on the Incidence, Risk Factors and Survival

Journal of Clinical Medicine, 2021
The peritoneum is a common metastatic site in gastric cancer. This systematic review provides an overview of the incidence, risk factors and survival of synchronous peritoneal metastases from gastric cancer.
Robin Lurvink, Grard Nieuwenhuijzen, Misha Luyer   +2 more
exaly   +2 more sources

Metal-enriched HSP90 nanoinhibitor overcomes heat resistance in hyperthermic intraperitoneal chemotherapy used for peritoneal metastases

Molecular Cancer, 2023
Clinical hyperthermic intraperitoneal chemotherapy (HIPEC) is regarded as a potential treatment that can prolong survival of patients with peritoneal metastases after cytoreductive surgery.
Qiang Wang, Peng Liu, Yingfei Wen, Kuan Li, Bo Bi, Bin-bin Li, Miaojuan Qiu, Shiqiang Zhang, You Li, Jia Li, Hengxing Chen, Yuan Yin, Leli Zeng, Changhua Zhang, Yulong He, Jing Zhao   +15 more
doaj   +2 more sources

Emerging therapeutic approaches for peritoneal metastases from gastrointestinal cancers

Molecular Therapy: Oncology
Peritoneal metastases from gastrointestinal malignancies present difficult management decisions, with options consisting primarily of systemic chemotherapy or major surgery with or without hyperthermic intraperitoneal chemotherapy.
Aleksandra Sikora, Kevin M. Sullivan, Sean Dineen, Mustafa Raoof, Aleksandra Karolak   +4 more
doaj   +2 more sources

Role of Peritoneal Mesothelial Cells in the Progression of Peritoneal Metastases

Cancers, 2022
Simple Summary Peritoneal mesothelial cells (PMCs) are the first cell layer to encounter peritoneal tumors, thereby affecting their progression. In the past, PMCs were considered a barrier to the intraperitoneal implantation and metastasis of tumors ...
Junliang Li, T. Guo
semanticscholar   +3 more sources

Review of Regional Therapies for Gastric Cancer with Peritoneal Metastases

Cancers, 2022
Simple Summary Gastric cancer is usually diagnosed at late stages and is associated with poor five-year survival rates. Metastasis to the peritoneal cavity is common and leads to even worse outcomes.

exaly   +2 more sources

Peritoneal Metastases [PDF]

Gastroenterology Research and Practice, 2012
Yutaka Yonemura, Yan Li, Paul H. Sugarbaker, Pompiliu Piso   +3 more
doaj   +4 more sources

Diaphragmatic peritoneal metastases mimicking liver metastases [PDF]

Pleura and Peritoneum, 2021
Noiret Barbara, Eveno Clarisse
doaj   +3 more sources