Local pulmonary drug delivery in the preterm rabbit: feasibility and efficacy of daily intratracheal injections [PDF]
American Journal of Physiology - Lung cellular and Molecular Physiology, 2019 Recent clinical trials in newborns have successfully used surfactant as a drug carrier for an active compound, to minimize systemic exposure. To investigate the translational potential of surfactant-compound mixtures and other local therapeutics, a ...
Thomas Salaets +14 more
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Pulmonary toxicity of well-dispersed cerium oxide nanoparticles following intratracheal instillation and inhalation [PDF]
Journal of nanoparticle research, 2015 We performed inhalation and intratracheal instillation studies of cerium dioxide (CeO2) nanoparticles in order to investigate their pulmonary toxicity, and observed pulmonary inflammation not only in the acute and but also in the chronic phases.
Yasuo Morimoto +14 more
openalex +2 more sources
Intranasal H5N1 vaccines, adjuvanted with chitosan derivatives, protect ferrets against highly pathogenic influenza intranasal and intratracheal challenge [PDF]
PLoS ONE, 2014 We investigated the protective efficacy of two intranasal chitosan (CSN and TM-CSN) adjuvanted H5N1 Influenza vaccines against highly pathogenic avian Influenza (HPAI) intratracheal and intranasal challenge in a ferret model. Six groups of 6 ferrets were
Catchpole, A. (Andrew) +15 more
core +2 more sources
Particle and Fibre Toxicology, 2022 Background A mounting number of studies have been documenting the carcinogenic potential of multiwalled carbon nanotubes (MWCNTs); however, only a few studies have evaluated the pulmonary carcinogenicity of MWCNTs in vivo.
M. Hojo +20 more
semanticscholar +1 more source
Scientific Reports, 2021 Due to frequent and often severe lung affections caused by COVID-19, murine models of acute respiratory distress syndrome (ARDS) are increasingly used in experimental lung research.
F. Khadangi +11 more
semanticscholar +1 more source
PLoS ONE, 2021 Infectious pneumonia induced by multidrug resistant (MDR) Acinetobacter baumannii strains is among the most common and deadly forms of healthcare acquired infections.
G. Bergamini +7 more
semanticscholar +1 more source
Effectiveness of high-flow nasal cannula therapy on clinical outcomes in adults with COVID-19: A systematic review [PDF]
Canadian Journal of Respiratory Therapy, 2023 Introduction/Background: Coronavirus disease 2019 (COVID-19) has high transmissibility and mortality rates. High-flow nasal cannula therapy (HFNC) might reduce the need for orotracheal intubation, easing the burden on the health system caused by COVID-19.
Daiana Gonçalves Arruda +2 more
doaj +1 more source
A comparison of the results from intra-pleural and intra-peritoneal studies with those from inhalation and intratracheal tests for the assessment of pulmonary responses to inhalable dusts and fibres. [PDF]
, 2016 The aim of this paper is to compare results from inhalation studies with those from intraperitoneal and intrapleural tests, where available, for a number of fibrous and particulate test materials.
Bevan, Ruth +2 more
core +2 more sources
Anaesthetic Management of Pyelolithotomy Patient with Restricted Mouth Opening due to Previous Mandibular Surgery- A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2023 Anaesthetic management of a patient with compromised kidney function, who had restricted mouth opening due to previous surgery for mandibular fracture requiring general anaesthesia, is a challenge for anaesthesiologists.
Kala Balasubramanian +1 more
doaj +1 more source
Emergency front of neck airway: What do trainers in the UK teach? A national survey
Journal of Anaesthesiology Clinical Pharmacology, 2019 Background and Aims: Front of neck airway (FONA) is the final step to deliver oxygen in the difficult airway management algorithms. The Difficult Airway Society 2015 guidelines have recommended a standardized scalpel cricothyroidotomy technique for an ...
Ilyas Qazi +4 more
doaj +1 more source