Results 11 to 20 of about 76,026 (337)

Intranasal H5N1 vaccines, adjuvanted with chitosan derivatives, protect ferrets against highly pathogenic influenza intranasal and intratracheal challenge [PDF]

PLoS ONE, 2014
We investigated the protective efficacy of two intranasal chitosan (CSN and TM-CSN) adjuvanted H5N1 Influenza vaccines against highly pathogenic avian Influenza (HPAI) intratracheal and intranasal challenge in a ferret model. Six groups of 6 ferrets were
Catchpole, A. (Andrew), Cox, R. (Rebecca), Hinchcliffe, M. (Michael), Knight, A. (Alastair), Lambkin-Williams, R. (Rob), Lapini, G. (Giulia), Mann, A.J. (Alex), Montomoli, E. (Emanuele), Noulin, N. (Nicolas), Osterhaus, A.D.M.E. (Albert), Oxford, J., Piccirella, S. (Simona), Smith, A. (Alan), Stittelaar, K.J. (Koert), Veldhuis Kroeze, E.J.B. (Edwin), Waal, L. (Leon) de   +15 more
core   +2 more sources

Two-year intermittent exposure of a multiwalled carbon nanotube by intratracheal instillation induces lung tumors and pleural mesotheliomas in F344 rats

Particle and Fibre Toxicology, 2022
Background A mounting number of studies have been documenting the carcinogenic potential of multiwalled carbon nanotubes (MWCNTs); however, only a few studies have evaluated the pulmonary carcinogenicity of MWCNTs in vivo.
M. Hojo, A. Maeno, Y. Sakamoto, Aya Ohnuki, Y. Tada, Y. Yamamoto, K. Ikushima, Ryota Inaba, Jin Suzuki, Y. Taquahashi, Satoshi Yokota, Norihiro Kobayashi, M. Ohnishi, Y. Goto, T. Numano, H. Tsuda, D. Alexander, J. Kanno, A. Hirose, A. Inomata, D. Nakae   +20 more
semanticscholar   +1 more source

Intranasal versus intratracheal exposure to lipopolysaccharides in a murine model of acute respiratory distress syndrome

Scientific Reports, 2021
Due to frequent and often severe lung affections caused by COVID-19, murine models of acute respiratory distress syndrome (ARDS) are increasingly used in experimental lung research.
F. Khadangi, Anne-Sophie Forgues, S. Tremblay-Pitre, A. Dufour-Mailhot, C. Henry, M. Boucher, M. Beaulieu, M. Morissette, L. Fereydoonzad, David Brunet, A. Robichaud, Y. Bossé   +11 more
semanticscholar   +1 more source

Mouse pneumonia model by Acinetobacter baumannii multidrug resistant strains: Comparison between intranasal inoculation, intratracheal instillation and oropharyngeal aspiration techniques

PLoS ONE, 2021
Infectious pneumonia induced by multidrug resistant (MDR) Acinetobacter baumannii strains is among the most common and deadly forms of healthcare acquired infections.
G. Bergamini, M. Perico, S. Di Palma, Daniela Sabatini, F. Andreetta, R. Defazio, A. Felici, L. Ferrari   +7 more
semanticscholar   +1 more source

Conventional Blind Method Versus SORT Manoeuvre of Nasogastric Tube Insertion in Anaesthetised Patients: A Randomised Clinical Study [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: Nasogastric Tube (NGT) placement is frequently performed in the preoperative period and critical care scenario. The SORT manoeuvre, a comparatively new method of NGT placement, is comprised of four components such as Sniffing position ...
SAROOJINI DIVYAA DHAKAL, SUSANTA SARKAR, CHIRANJIB BHATTACHARYYA, Mohanchandra Mandal   +3 more
doaj   +1 more source

Comparison of glottic visualisation through supraglottic airway device (SAD) using bronchoscope in the ramped versus supine 'sniffing air' position: A pilot feasibility study

Indian Journal of Anaesthesia, 2020
Background and Aims: Airway management in obese patients is associated with increased risk of difficult airway and intubation. After failed intubation, supraglottic airway-guided flexible bronchoscopic intubation (SAGFBI) may be required. It is uncertain
Wan Yen Lim, Stephanie Fook-Chong, Patrick Wong   +2 more
doaj   +1 more source

Effectiveness of high-flow nasal cannula therapy on clinical outcomes in adults with COVID-19: A systematic review [PDF]

Canadian Journal of Respiratory Therapy, 2023
Introduction/Background: Coronavirus disease 2019 (COVID-19) has high transmissibility and mortality rates. High-flow nasal cannula therapy (HFNC) might reduce the need for orotracheal intubation, easing the burden on the health system caused by COVID-19.
Daiana Gonçalves Arruda, George Alvício Kieling, Lucélia Luna Melo-Diaz   +2 more
doaj   +1 more source

The effect of tracheal tube size on air leak around the cuffs [PDF]

Korean Journal of Anesthesiology, 2011
BackgroundThis randomized single-blinded, cross-over study was done to evaluate the influence of the size of tracheal tubes on air leaks around the cuffs.MethodsIn a benchtop model, the number of longitudinal folds on the cuffs was evaluated for ...
Jin-Young Hwang, Sang-Hyun Park, Sung-Hee Han, Seong-Joo Park, Soo-kyung Park, Jin-Hee Kim   +5 more
doaj   +1 more source

Anaesthetic Management of Pyelolithotomy Patient with Restricted Mouth Opening due to Previous Mandibular Surgery- A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2023
Anaesthetic management of a patient with compromised kidney function, who had restricted mouth opening due to previous surgery for mandibular fracture requiring general anaesthesia, is a challenge for anaesthesiologists.
Kala Balasubramanian, Bhagya Vardhan Botta   +1 more
doaj   +1 more source

Post-Exposure Anti-Ricin Treatment Protects Swine against Lethal Systemic and Pulmonary Exposures

Toxins, 2020
Ricin, a plant-derived toxin originating from the seeds of Ricinus communis (castor bean plant), is one of the most lethal toxins known. To date, there is no approved post-exposure therapy for ricin exposures.
Reut Falach, Anita Sapoznikov, Yentl Evgy, Moshe Aftalion, Arik Makovitzki, Avi Agami, Avishai Mimran, Elad Lerer, Alon Ben David, Ran Zichel, Shahaf Katalan, Amir Rosner, Tamar Sabo, Chanoch Kronman, Yoav Gal   +14 more
doaj   +1 more source